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Information on EC 2.1.1.345 - psilocybin synthase

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EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.345 psilocybin synthase
IUBMB Comments
Isolated from the fungus Psilocybe cubensis. The product, psilocybin, is a psychoactive compound.
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The expected taxonomic range for this enzyme is: Psilocybe
Synonyms
PsiM, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 S-adenosyl-L-methionine + 4-hydroxytryptamine 4-phosphate = 2 S-adenosyl-L-homocysteine + psilocybin
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overall reaction
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S-adenosyl-L-methionine + 4-hydroxy-N-methyltryptamine 4-phosphate = S-adenosyl-L-homocysteine + psilocybin
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(1b)
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S-adenosyl-L-methionine + 4-hydroxytryptamine 4-phosphate = S-adenosyl-L-homocysteine + 4-hydroxy-N-methyltryptamine 4-phosphate
show the reaction diagram
(1a)
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