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Information on EC 2.1.1.348 - mRNA m6A methyltransferase

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EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.348 mRNA m6A methyltransferase
IUBMB Comments
This enzyme, found in eukaryotes, methylates adenines in mRNA with the consensus sequence RRACH.
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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
Synonyms
mettl3, mettl14, ythdf2, methyltransferase-like 3, methyltransferase like 3, mettl3/mettl14, methyltransferase-like 14, n6-adenosine-methyltransferase, mettl3-mettl14 methyltransferase complex, m6a mtase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + adenine in mRNA = S-adenosyl-L-homocysteine + N6-methyladenine in mRNA
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