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Information on EC 2.3.1.217 - curcumin synthase

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EC Tree
     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.217 curcumin synthase
IUBMB Comments
A polyketide synthase from the plant Curcuma longa (turmeric). Three isoforms exist, CURS1, CURS2 and CURS3. While CURS1 and CURS2 prefer feruloyl-CoA as a starter substrate, CURS3 can accept 4-coumaroyl-CoA equally well (see EC 2.3.1.219, demethoxycurcumin synthase).
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
curs1, curs3, curcumin synthase, curs2, curcumin synthase 1, curcumin synthase 2, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
feruloyl-CoA + feruloylacetyl-CoA + H2O = 2 CoA + curcumin + CO2
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