Disease on EC 2.3.1.225 - protein S-acyltransferase
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Alopecia
Mice with alopecia, osteoporosis, and systemic amyloidosis due to mutation in Zdhhc13, a gene coding for palmitoyl acyltransferase.
Amyloidosis
Mice with alopecia, osteoporosis, and systemic amyloidosis due to mutation in Zdhhc13, a gene coding for palmitoyl acyltransferase.
Anthrax
Anthrax toxin requires ZDHHC5-mediated palmitoylation of its surface-processing host enzymes.
Brain Injuries
Palmitoyl Acyltransferase zD17 Mediates Neuronal Responses in Acute Ischemic Brain Injury by Regulating JNK Activation in a Signaling Module.
Breast Neoplasms
LXR Activation Down-regulates Lipid Raft Markers FLOT2 and DHHC5 in MCF-7 Breast Cancer Cells.
Breast Neoplasms
Protein Acyltransferase DHHC3 Regulates Breast Tumor Growth, Oxidative Stress, and Senescence.
Carcinoma
Nitrodibenzofuran: a One- and Two-Photon Sensitive Protecting Group that is Superior to Brominated Hydroxycoumarin for Thiol Caging in Peptides.
Carcinoma, Hepatocellular
Prognostic significance of cytoskeleton-associated membrane protein 4 and its palmitoyl acyltransferase DHHC2 in hepatocellular carcinoma.
Carcinoma, Non-Small-Cell Lung
Systematic siRNA Screen Unmasks NSCLC Growth Dependence by Palmitoyltransferase DHHC5.
Cardiomyopathies
Palmitoyl acyltransferase Aph2 in cardiac function and the development of cardiomyopathy.
Dwarfism
PROTEIN S-ACYL TRANSFERASE10 Is Critical for Development and Salt Tolerance in Arabidopsis.
Glioma
DHHC protein family targets different subsets of glioma stem cells in specific niches.
Glioma
EZH2 Palmitoylation Mediated by ZDHHC5 in p53-Mutant Glioma Drives Malignant Development and Progression.
Herpes Simplex
The Absence of DHHC3 Affects Primary and Latent Herpes Simplex Virus 1 Infection.
Huntington Disease
Dysregulated striatal neuronal processing and impaired motor behavior in mice lacking huntingtin interacting protein 14 (HIP14).
Huntington Disease
Palmitoylation of huntingtin by HIP14 is essential for its trafficking and function.
Huntington Disease
The Palmitoyl acyltransferase HIP14 Shares a High Proportion of Interactors with Huntingtin: Implications for a Role in the Pathogenesis of Huntington Disease.
Huntington Disease
Tracking brain palmitoylation change: predominance of glial change in a mouse model of Huntington's disease.
Infections
Purification of Recombinant DHHC Proteins Using an Insect Cell Expression System.
Infections
The Absence of DHHC3 Affects Primary and Latent Herpes Simplex Virus 1 Infection.
Infertility
PROTEIN S-ACYL TRANSFERASE10 Is Critical for Development and Salt Tolerance in Arabidopsis.
Insulin Resistance
Brain insulin resistance impairs hippocampal synaptic plasticity and memory by increasing GluA1 palmitoylation through FoxO3a.
Insulinoma
A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic ?-Cells.
Lung Abscess
Whole-genome sequence of Corynebacterium pseudotuberculosis PAT10 strain isolated from sheep in Patagonia, Argentina.
Lung Neoplasms
Systematic siRNA Screen Unmasks NSCLC Growth Dependence by Palmitoyltransferase DHHC5.
Malaria
The Plasmodium palmitoyl-S-acyl-transferase DHHC2 is essential for ookinete morphogenesis and malaria transmission.
Neoplasm Metastasis
miR-96-5p enhances cell proliferation and invasion via targeted regulation of ZDHHC5 in gastric cancer.
Neoplasms
Artemisinin inhibits NRas palmitoylation by targeting the protein acyltransferase ZDHHC6.
Neoplasms
Discovery and characterization of inhibitors of human palmitoyl acyltransferases.
Neoplasms
Huntingtin interacting protein 14 is an oncogenic human protein: palmitoyl acyltransferase.
Neoplasms
Identification of CKAP4/p63 as a major substrate of the palmitoyl acyltransferase DHHC2, a putative tumor suppressor, using a novel proteomics method.
Neoplasms
Inhibiting PD-L1 palmitoylation enhances T-cell immune responses against tumours.
Neoplasms
miR-96-5p enhances cell proliferation and invasion via targeted regulation of ZDHHC5 in gastric cancer.
Neoplasms
Palmitoylation of cytoskeleton associated protein 4 by DHHC2 regulates antiproliferative factor-mediated signaling.
Neoplasms
Protein Acyltransferase DHHC3 Regulates Breast Tumor Growth, Oxidative Stress, and Senescence.
Neoplasms
Retraction: miR-96-5p enhances cell proliferation and invasion via targeted regulation of ZDHHC5 in gastic cancer.
Neoplasms
S-acylated Golga7b stabilises DHHC5 at the plasma membrane to regulate cell adhesion.
Neoplasms
Systematic siRNA Screen Unmasks NSCLC Growth Dependence by Palmitoyltransferase DHHC5.
Nervous System Diseases
Palmitoyl Acyltransferase zD17 Mediates Neuronal Responses in Acute Ischemic Brain Injury by Regulating JNK Activation in a Signaling Module.
Osteoporosis
Mice with alopecia, osteoporosis, and systemic amyloidosis due to mutation in Zdhhc13, a gene coding for palmitoyl acyltransferase.
Paralysis
Sudden death due to paralysis and synaptic and behavioral deficits when Hip14/Zdhhc17 is deleted in adult mice.
Stomach Neoplasms
miR-96-5p enhances cell proliferation and invasion via targeted regulation of ZDHHC5 in gastric cancer.
Tuberculosis
Characterization of protein acyltransferase function of recombinant purified GlnA1 from Mycobacterium tuberculosis: A moon lighting property.
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