Disease on EC 2.4.99.6 - N-acetyllactosaminide alpha-2,3-sialyltransferase
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Abortion, Habitual
Expression of the Carbohydrate Lewis Antigen, Sialyl Lewis A, Sialyl Lewis X, Lewis X, and Lewis Y in the Placental Villi of Patients With Unexplained Miscarriages.
Abortion, Spontaneous
Expression of the Carbohydrate Lewis Antigen, Sialyl Lewis A, Sialyl Lewis X, Lewis X, and Lewis Y in the Placental Villi of Patients With Unexplained Miscarriages.
Adenocarcinoma
?2,3-sialyltransferase ST3Gal IV promotes migration and metastasis in pancreatic adenocarcinoma cells and tends to be highly expressed in pancreatic adenocarcinoma tissues.
Adenocarcinoma
alpha2,3-sialyltransferase ST3Gal III modulates pancreatic cancer cell motility and adhesion in vitro and enhances its metastatic potential in vivo.
Adenocarcinoma
Knockdown of ?2,3-Sialyltransferases Impairs Pancreatic Cancer Cell Migration, Invasion and E-selectin-Dependent Adhesion.
Adenocarcinoma
Pancreatic cancer cell glycosylation regulates cell adhesion and invasion through the modulation of ?2?1 integrin and E-cadherin function.
Adenocarcinoma
ST3Gal IV Mediates the Growth and Proliferation of Cervical Cancer Cells In Vitro and In Vivo Via the Notch/p21/CDKs Pathway.
Autoimmune Diseases
The expanding role of ?2-3 sialylation for leukocyte trafficking in vivo.
Breast Neoplasms
Multiplex reverse transcription polymerase chain reaction assessment of sialyltransferase expression in human breast cancer.
Breast Neoplasms
Prognostic value of tumoral sialyltransferase expression and circulating E-selectin concentrations in node-negative breast cancer patients.
Breast Neoplasms
Regulation of sialyltransferase expression by estradiol and 4-OH-tamoxifen in the human breast cancer cell MCF-7.
Breast Neoplasms
ST3Gal III modulates breast cancer cell adhesion and invasion by altering the expression of invasion-related molecules.
Breast Neoplasms
ST3Gal IV Mediates the Growth and Proliferation of Cervical Cancer Cells In Vitro and In Vivo Via the Notch/p21/CDKs Pathway.
Carcinogenesis
Glycosyltransferase expression in human colonic tissue examined by oligonucleotide arrays.
Carcinoma
"Aberrant sialylation plays a significant role in oral squamous cell carcinoma progression".
Carcinoma
Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases.
Carcinoma
Altered mRNA expression of sialyltransferase in squamous cell carcinomas of the cervix.
Carcinoma
Carcinoembryonic antigen carrying SLeX as a new biomarker of more aggressive gastric carcinomas.
Carcinoma
Characterization of two glycolipid: alpha 2-3sialyltransferases, SAT-3 (CMP-NeuAc:nLcOse4Cer alpha 2-3sialyltransferase) and SAT-4 (CMP-NeuAc:GgOse4Cer alpha 2-3sialyltransferase), from human colon carcinoma (Colo 205) cell line.
Carcinoma
Cloning and expression of SAT-3 involved in SA-Le(x) biosynthesis: inhibition studies with polyclonal antibody against GST-SAT-3 fusion protein.
Carcinoma
DNA hypermethylation contributes to incomplete synthesis of carbohydrate determinants in gastrointestinal cancer.
Carcinoma
Expression of sialyltransferase family members in cervix squamous cell carcinoma correlates with lymph node metastasis.
Carcinoma
Expression of ST3GAL4 leads to SLe(x) expression and induces c-Met activation and an invasive phenotype in gastric carcinoma cells.
Carcinoma
ST3Gal IV Mediates the Growth and Proliferation of Cervical Cancer Cells In Vitro and In Vivo Via the Notch/p21/CDKs Pathway.
Carcinoma, Hepatocellular
Differences in CD75s- and iso-CD75s-ganglioside content and altered mRNA expression of sialyltransferases ST6GAL1 and ST3GAL6 in human hepatocellular carcinomas and nontumoral liver tissues.
Carcinoma, Hepatocellular
Interleukin-1beta induces sialyl Lewis X on hepatocellular carcinoma HuH-7 cells via enhanced expression of ST3Gal IV and FUT VI gene.
Carcinoma, Hepatocellular
Sialyltransferase ST3GAL6 mediates the effect of microRNA-26a on cell growth, migration, and invasion in hepatocellular carcinoma through the protein kinase B/mammalian target of rapamycin pathway.
Carcinoma, Renal Cell
Clinical significance of ST3Gal IV expression in human renal cell carcinoma.
Carcinoma, Squamous Cell
Altered mRNA expression of sialyltransferase in squamous cell carcinomas of the cervix.
Carcinoma, Squamous Cell
Expression of sialyltransferase family members in cervix squamous cell carcinoma correlates with lymph node metastasis.
Colorectal Neoplasms
Sialyltransferase activity and hepatic tumor growth in a nude mouse model of colorectal cancer metastases.
Colorectal Neoplasms
Up-regulation of a set of glycosyltransferase genes in human colorectal cancer.
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
A novel nonsense and inactivating variant of ST3GAL3 in two infant siblings suffering severe epilepsy and expressing circulating CA19.9.
Epilepsy
A novel nonsense and inactivating variant of ST3GAL3 in two infant siblings suffering severe epilepsy and expressing circulating CA19.9.
Epilepsy, Temporal Lobe
Sialyltransferase ST3Gal IV deletion protects against temporal lobe epilepsy.
Hypertension, Pulmonary
Multiplex reverse transcription polymerase chain reaction assessment of sialyltransferase expression in peripheral blood mononuclear cells in systemic sclerosis.
Influenza in Birds
The expression pattern and histological distribution of sialyltransferases ST3Gal III in yellow chicken.
Intellectual Disability
A novel variant of ST3GAL3 causes non-syndromic autosomal recessive intellectual disability in Iranian patients.
Intellectual Disability
Phenotype of ST3GAL3 deficient patients: A case and review of the literature.
Intellectual Disability
ST3GAL3 mutations impair the development of higher cognitive functions.
Leukemia
UDP-GlcNAc:Galbeta1-->3GalNAc (GlcNAc to GalNAc) beta1-->6N-acetylglucosaminyltransferase holds a key role on the control of CD15s expression in human pre-B lymphoid cell lines.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Downregulation of miR-224 and let-7i contribute to cell survival and chemoresistance in chronic myeloid leukemia cells by regulating ST3GAL IV expression.
Lymphatic Metastasis
Expression of sialyltransferase family members in cervix squamous cell carcinoma correlates with lymph node metastasis.
Melanoma
Characterization of two glycolipid: alpha 2-3sialyltransferases, SAT-3 (CMP-NeuAc:nLcOse4Cer alpha 2-3sialyltransferase) and SAT-4 (CMP-NeuAc:GgOse4Cer alpha 2-3sialyltransferase), from human colon carcinoma (Colo 205) cell line.
Melanoma
Molecular cloning of a novel alpha2,3-sialyltransferase (ST3Gal VI) that sialylates type II lactosamine structures on glycoproteins and glycolipids.
Mouth Neoplasms
"Aberrant sialylation plays a significant role in oral squamous cell carcinoma progression".
Multiple Myeloma
lncRNA ST3GAL6?AS1 promotes invasion by inhibiting hnRNPA2B1?mediated ST3GAL6 expression in multiple myeloma.
Multiple Myeloma
The sialyltransferase ST3GAL6 influences homing and survival in multiple myeloma.
n-acetyllactosaminide alpha-2,3-sialyltransferase deficiency
A patient-specific induced pluripotent stem cell model for West syndrome caused by ST3GAL3 deficiency.
n-acetyllactosaminide alpha-2,3-sialyltransferase deficiency
Phenotype of ST3GAL3 deficient patients: A case and review of the literature.
n-acetyllactosaminide alpha-2,3-sialyltransferase deficiency
Sialyltransferase ST3Gal-IV operates as a dominant modifier of hemostasis by concealing asialoglycoprotein receptor ligands.
n-acetyllactosaminide alpha-2,3-sialyltransferase deficiency
The sialyltransferase ST3Gal-IV guides murine T-cell progenitors to the thymus.
n-acetyllactosaminide alpha-2,3-sialyltransferase deficiency
West syndrome caused by ST3Gal-III deficiency.
Neoplasm Metastasis
"Aberrant sialylation plays a significant role in oral squamous cell carcinoma progression".
Neoplasm Metastasis
?2,3-sialyltransferase ST3Gal IV promotes migration and metastasis in pancreatic adenocarcinoma cells and tends to be highly expressed in pancreatic adenocarcinoma tissues.
Neoplasm Metastasis
alpha2,3-sialyltransferase ST3Gal III modulates pancreatic cancer cell motility and adhesion in vitro and enhances its metastatic potential in vivo.
Neoplasm Metastasis
Correlation of glycosyltransferases mRNA expression in extrahepatic bile duct carcinoma with clinical pathological characteristics.
Neoplasm Metastasis
Expression of sialyltransferase family members in cervix squamous cell carcinoma correlates with lymph node metastasis.
Neoplasm Metastasis
Glycosyltransferase expression in human colonic tissue examined by oligonucleotide arrays.
Neoplasm Metastasis
Knockdown of ?2,3-Sialyltransferases Impairs Pancreatic Cancer Cell Migration, Invasion and E-selectin-Dependent Adhesion.
Neoplasms
?2,3-sialyltransferase ST3Gal IV promotes migration and metastasis in pancreatic adenocarcinoma cells and tends to be highly expressed in pancreatic adenocarcinoma tissues.
Neoplasms
Alpha2,3-sialyltransferase III knockdown sensitized ovarian cancer cells to cisplatin-induced apoptosis.
Neoplasms
alpha2,3-sialyltransferase ST3Gal III modulates pancreatic cancer cell motility and adhesion in vitro and enhances its metastatic potential in vivo.
Neoplasms
Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases.
Neoplasms
Clinical relevance of sialyltransferases ST6GAL-I and ST3GAL-III in gastric cancer.
Neoplasms
Correlation between Heterogeneous Expression of Sialyltransferases and MUC16 in Ovarian Tumor Tissues.
Neoplasms
Correlation of glycosyltransferases mRNA expression in extrahepatic bile duct carcinoma with clinical pathological characteristics.
Neoplasms
Differences in CD75s- and iso-CD75s-ganglioside content and altered mRNA expression of sialyltransferases ST6GAL1 and ST3GAL6 in human hepatocellular carcinomas and nontumoral liver tissues.
Neoplasms
Expression of ST3GAL4 leads to SLe(x) expression and induces c-Met activation and an invasive phenotype in gastric carcinoma cells.
Neoplasms
Glycosyltransferases as marker genes for the quantitative polymerase chain reaction-based detection of circulating tumour cells from blood samples of patients with breast cancer undergoing adjuvant therapy.
Neoplasms
Hypoxia and serum deprivation induces glycan alterations in triple negative breast cancer cells.
Neoplasms
Identification of glycogene-type and validation of ST3GAL6 as a biomarker predicts clinical outcome and cancer cell invasion in urinary bladder cancer.
Neoplasms
LncRNA ST3Gal6-AS1/ST3Gal6 axis mediates colorectal cancer progression by regulating ?-2,3 sialylation via PI3K/Akt signaling.
Neoplasms
Multiplex reverse transcription polymerase chain reaction assessment of sialyltransferase expression in human breast cancer.
Neoplasms
Pancreatic cancer cell glycosylation regulates cell adhesion and invasion through the modulation of ?2?1 integrin and E-cadherin function.
Neoplasms
Prognostic value of tumoral sialyltransferase expression and circulating E-selectin concentrations in node-negative breast cancer patients.
Neoplasms
Pseudomonas aeruginosa pyocyanin modulates mucin glycosylation with sialyl-Lewis(x) to increase binding to airway epithelial cells.
Neoplasms
Sialyltransferase ST3GAL6 mediates the effect of microRNA-26a on cell growth, migration, and invasion in hepatocellular carcinoma through the protein kinase B/mammalian target of rapamycin pathway.
Neoplasms
Siglec1-expressing subcapsular sinus macrophages provide soil for melanoma lymph node metastasis.
Neoplasms
The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer.
Neoplasms
The sialyltransferase ST3GAL6 influences homing and survival in multiple myeloma.
Neoplasms
Unexpected distribution of CA19.9 and other type 1 chain Lewis antigens in normal and cancer tissues of colon and pancreas: Importance of the detection method and role of glycosyltransferase regulation.
Ovarian Neoplasms
Alpha2,3-sialyltransferase III knockdown sensitized ovarian cancer cells to cisplatin-induced apoptosis.
Ovarian Neoplasms
Correlation between Heterogeneous Expression of Sialyltransferases and MUC16 in Ovarian Tumor Tissues.
Ovarian Neoplasms
ST3Gal3 confers paclitaxel?mediated chemoresistance in ovarian cancer cells by attenuating caspase?8/3 signaling.
Pancreatic Neoplasms
alpha2,3-sialyltransferase ST3Gal III modulates pancreatic cancer cell motility and adhesion in vitro and enhances its metastatic potential in vivo.
Pneumonia
Sialyltransferase ST3Gal-III regulates Siglec-F ligand formation and eosinophilic lung inflammation in mice.
Prostatic Neoplasms
Analysis of the specificity of sialyltransferases toward mucin core 2, globo, and related structures. identification of the sialylation sequence and the effects of sulfate, fucose, methyl, and fluoro substituents of the carbohydrate chain in the biosynthesis of selectin and siglec ligands, and novel sialylation by cloned alpha2,3(O)sialyltransferase.
Seizures
Differential expression of mRNAs for sialyltransferase isoenzymes induced in the hippocampus of mouse following kindled seizures.
Spasms, Infantile
A patient-specific induced pluripotent stem cell model for West syndrome caused by ST3GAL3 deficiency.
Stomach Neoplasms
Altered mRNA expressions of sialyltransferases in human gastric cancer tissues.
Stomach Neoplasms
Analysis of the Effect of Increased ?2,3-Sialylation on RTK Activation in MKN45 Gastric Cancer Spheroids Treated with Crizotinib.
Stomach Neoplasms
Carcinoembryonic antigen carrying SLeX as a new biomarker of more aggressive gastric carcinomas.
Stomach Neoplasms
Clinical relevance of sialyltransferases ST6GAL-I and ST3GAL-III in gastric cancer.
Stomach Neoplasms
DNA hypermethylation contributes to incomplete synthesis of carbohydrate determinants in gastrointestinal cancer.
Thrombocytopenia
Sialyltransferase ST3Gal-IV operates as a dominant modifier of hemostasis by concealing asialoglycoprotein receptor ligands.
Urinary Bladder Neoplasms
Identification of glycogene-type and validation of ST3GAL6 as a biomarker predicts clinical outcome and cancer cell invasion in urinary bladder cancer.
Uterine Cervical Neoplasms
Altered mRNA expression of sialyltransferase in squamous cell carcinomas of the cervix.
Uterine Cervical Neoplasms
Expression of sialyltransferase family members in cervix squamous cell carcinoma correlates with lymph node metastasis.
Uterine Cervical Neoplasms
ST3Gal IV Mediates the Growth and Proliferation of Cervical Cancer Cells In Vitro and In Vivo Via the Notch/p21/CDKs Pathway.
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