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Information on EC 2.7.1.223 - aminoimidazole riboside kinase

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IUBMB Comments
The enzyme, characterized from the bacterium Salmonella enterica, can phosphorylate exogeneously-provided 5-amino-1-(beta-D-ribosyl)imidazole to form 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole (AIR), an important intermediate in the production of both purine mononucleotides and the hydroxymethyl pyrimidine moiety of thiamine.
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The enzyme appears in viruses and cellular organisms
Synonyms
stm4066, vca0656, aminoimidazole riboside kinase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + 5-amino-1-(beta-D-ribosyl)imidazole = ADP + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole
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