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Information on EC 3.1.1.76 - poly(3-hydroxyoctanoate) depolymerase

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EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.1 Carboxylic-ester hydrolases
                3.1.1.76 poly(3-hydroxyoctanoate) depolymerase
IUBMB Comments
The main product after prolonged incubation is the dimer . Besides hydrolysing polymers of 3-hydroxyoctanoic acid, the enzyme also hydrolyses other polymers derived from medium-chain-length (C6-C12) hydroxyalkanoic acids and copolymers of mixtures of these. It also hydrolyses p-nitrophenyl esters of fatty acids. Polymers of short-chain-length hydroxyalkanoic acids such as poly[(R)-3-hydroxybutanoic acid] and poly[(R)-3-hydroxypentanoic acid] are not hydrolysed.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
phaz depolymerase, extracellular mcl-pha depolymerase, extracellular p(3ho) depolymerase, phazgk13, pho depolymerase, p(3ho) depolymerase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Hydrolyses the polyester poly{oxycarbonyl[(R)-2-pentylethylene]} to oligomers
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