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Alkaline mesentericopeptidase
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Asp v 13
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subtilisin-like serine protease
Bacillopeptidase A
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Bacillopeptidase B
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Bacillus gibsonii alkaline protease
Bacillus subtilis alkaline proteinase Bioprase
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cold active subtilisin-like serine proteinase
EC 3.4.4.16
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formerly, part transferred
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intracellular subtilisin protease
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mesenteroicopeptidase
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Peptidase, subtilo-, A
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Proteinase, Bacillus subtilis alkaline
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psychrophilic subtilisin-like protease
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SAS-1
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extensive homology to other plant subtilisin-like serine protease
saspase
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saspase: serine proteases exhibting aspase activity
Savinase 32.0 L EX
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senescence-associated subtilisin protease
Q0WWH7
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subtilase subfamily 1 member 9
Subtilisin amylosacchariticus
subtilisin Pr1-like protease
Subtilisin Sendai
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-
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subtilisin-like ookinete protein
subtilisin-like ookinete protein important for transmission
subtilisin-like protease AprV2
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subtilisin-like serine protease
thermo-active subtilisin-like serine protease
thermophilic thermitase
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trans-cinnamoyl-subtilisin
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acyl-enzyme covalent intermediate of the serine protese subtilisin Carlsberg
V. cholerae-secreted serine protease
AcpII
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Ak.1 protease
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Alcalase
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Alkaline protease
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alkaline serine protease
UniProt
alkaline serine protease
UniProt
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alkaline serine protease
Vibrio cholerae serotype O1 C6706
UniProt
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alkaline serine protease
UniProt
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aprE
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AtSBT1.9
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Bacillus gibsonii alkaline protease
GN111900.1
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Bacillus gibsonii alkaline protease
GN111900.1
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BgAP
GN111900.1
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cold active subtilisin-like serine proteinase
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cold active subtilisin-like serine proteinase
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EC 3.4.21.14
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formerly
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EC 3.4.21.14
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formerly included in
EC 3.4.21.14
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formerly included in
Fe protease
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Fe prtS8A
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IvaP
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IvaP
Vibrio cholerae serotype O1 C6706
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ORF2
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PbSOPT
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phytophase
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extensive homology to other plant subtilisin-like serine protease, phytaspase: a plant aspartate-specific protease
phytophase
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extensive homology to other plant subtilisin-like serine protease, phytaspase: a plant aspartate-specific protease
PIMMS2
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SAP
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SBL
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SES7
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SOPT
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subtilase
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subtilase subfamily 1 member 9
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subtilase subfamily 1 member 9
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subtilase-like protease
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subtilase-like protease
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subtilisin
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subtilisin 72
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subtilisin A
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Subtilisin amylosacchariticus
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from Bacillus subtilis var. amylosacchariticus
Subtilisin amylosacchariticus
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from Bacillus subtilis var. amylosacchariticus
Subtilisin amylosacchariticus
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from Bacillus subtilis var. amylosacchariticus
subtilisin BPN
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subtilisin Carlsberg
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651044, 653614, 653619, 685336, 685717, 685809, 686432, 688433, 688609, 689303, 689947, 707804, 709558, 732243
subtilisin DJ-4
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strain DJ-4
subtilisin DJ-4
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strain DJ-4
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Subtilisin DY
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Subtilisin E
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-
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subtilisin E-S7
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subtilisin JB1
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subtilisin Pr1-like protease
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subtilisin Pr1-like protease
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subtilisin QK
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Subtilisin S41
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-
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subtilisin Sph
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subtilisin-like ookinete protein
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subtilisin-like ookinete protein
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subtilisin-like ookinete protein
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subtilisin-like ookinete protein important for transmission
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subtilisin-like ookinete protein important for transmission
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subtilisin-like ookinete protein important for transmission
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subtilisin-like protease
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subtilisin-like protease
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subtilisin-like protease
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subtilisin-like protease
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subtilisin-like protease
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subtilisin-like protease
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subtilisin-like protease
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subtilisin-like protease
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subtilisin-like protease
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subtilisin-like protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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-
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
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subtilisin-like serine protease
Vibrio cholerae serotype O1 C6706
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subtilisin-like serine protease
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thermo-active subtilisin-like serine protease
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thermo-active subtilisin-like serine protease
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thermo-active subtilisin-like serine protease
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thermostable subtilisin
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thermostable subtilisin
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ThSS45
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V. cholerae-secreted serine protease
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V. cholerae-secreted serine protease
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V. cholerae-secreted serine protease
Vibrio cholerae serotype O1 C6706
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V. cholerae-secreted serine protease
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VC_0157
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VC_0157
Vibrio cholerae serotype O1 C6706
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vPR
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additional information
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species variants include subtilisin BPN' (also subtilisin B, subtilopeptidase B, subtilopeptidase C, Nagarse, Nagarse proteinase, subtilisin Novo, bacterial proteinase Novo) and subtilisin Carlsberg (subtilisin A, subtilopeptidase A, alcalase Novo), similar enzymes are produced by various Bacillus subtilis strains and other Bacillus species
additional information
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synonyms of subtilisin Carlsberg: subtilisin, subtilisin A, subtilopeptidase A, alcalase Novo, synonyms of subtilisin BPN': nagarse proteinase, Nagarse, BPN', subtilopeptidase C, synonyms of subtilisin Novo: bacterial proteinase Novo, subtilisin B, subtilopeptidase B
additional information
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species variants include subtilisin BPN' (also subtilisin B, subtilopeptidase B, subtilopeptidase C, Nagarse, Nagarse proteinase, subtilisin Novo, bacterial proteinase Novo) and subtilisin Carlsberg (subtilisin A, subtilopeptidase A, alcalase Novo), similar enzymes are produced by various Bacillus subtilis strains and other Bacillus species
additional information
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synonyms of subtilisin Carlsberg: subtilisin, subtilisin A, subtilopeptidase A, alcalase Novo, synonyms of subtilisin BPN': nagarse proteinase, Nagarse, BPN', subtilopeptidase C, synonyms of subtilisin Novo: bacterial proteinase Novo, subtilisin B, subtilopeptidase B
additional information
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the commercial enzyme subtilisin BPN' from Sigma: kinetic and physical properties indicate that the commercial enzyme is probably subtilisin Carlsberg isolated from Bacillus licheniformis, much work which has been performed on commercial subtilisin BPN' from 1975 up to 1985 must be revaluated
additional information
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synonyms of subtilisin Carlsberg: subtilisin, subtilisin A, subtilopeptidase A, alcalase Novo, synonyms of subtilisin BPN': nagarse proteinase, Nagarse, BPN', subtilopeptidase C, synonyms of subtilisin Novo: bacterial proteinase Novo, subtilisin B, subtilopeptidase B
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Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyses peptide amides
Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyses peptide amides
hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides. Mechanism
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Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyses peptide amides
hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides. Mechanism
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Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyses peptide amides
importance of tetrahedral intermediate formation in the catalytic mechanism of the serine protease subtilisin. Substrate binding induces the formation of a strong hydrogen bond or low-barrier hydrogen bond between histidine-57 and aspartate-102 that increases the pK(a) of the active site histidine, allowing it to be an effective general base catalyst for the formation of the tetrahedral intermediate and increasing the effective molarity of the catalytic hydroxyl group of serine-195, catalytic mechanism, overview
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Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyses peptide amides
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(R,S)-2-benzyl-3-(tert-butylsulfonyl)propionic acid + H2O
(R)-2-benzyl-3-(tert-butylsulfonyl)propionic ethyl ester + (S)-2-benzyl-3-(tert-butylsulfonyl)propionic acid + ethanol
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Substrates: -
Products: -
?
(R,S)-2-benzyl-3-[[1-methyl-1-((morpholin-4-yl)-carbonyl)ethyl]sulfonyl]propionic acid + H2O
(S)-2-benzyl-3-[[1-methyl-1-((morpholin-4-yl)-carbonyl)ethyl]sulfonyl]propionic acid + (R)-2-benzyl-3-[[1-methyl-1-((morpholin-4-yl)-carbonyl)ethyl]sulfonyl]propionic acid-ethyl ester + ethanol
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Substrates: -
Products: -
?
(R/S)-(2-methylpropyl)butanedioic acid diethyl ester + H2O
(S)-(2-methylpropyl)butanedioic acid diethyl ester + (R)-(2-methylpropyl)butanedioic acid 4-ethyl ester + ethanol
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Substrates: -
Products: -
?
1-phenylethanol + trifluoroethyl butyrate
?
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Substrates: -
Products: -
?
1-propanol + N-acetyl phenylalanine ethyl ester
?
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Substrates: -
Products: -
?
2 rac-1-(4-chlorophenyl)ethan-1-ol + vinyl butyrate
(1S)-1-(4-chlorophenyl)ethyl butyrate + (1R)-1-(4-chlorophenyl)ethan-1-ol + ?
Substrates: -
Products: -
?
2 rac-1-(4-methoxyphenyl)ethan-1-ol + vinyl butyrate
(1S)-1-(4-methoxyphenyl)ethyl butyrate + (1R)-1-(4-methoxyphenyl)ethan-1-ol + ?
Substrates: substrate only of mutant G165L/M221F, not of the wild-type enzyme
Products: -
?
2 rac-1-(4-methylphenyl)ethan-1-ol + vinyl butyrate
(1S)-1-(4-methylphenyl)ethyl butyrate + (1R)-1-(4-methylphenyl)ethan-1-ol + ?
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