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Reference on EC 3.4.22.14 - actinidain

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Brocklehurst, K.; O'Driscoll, M.; Kowlessur, D.; Phillips, I.R.; Templeton, W.; Thomas, E.W.; Topham, C.M.; Wharton, C.W.
The interplay of electrostatic and binding interactions determining active centre chemistry and catalytic activity in actinidin and papain [letter
Biochem. J.
257
309-310
1989
Actinidia chinensis
Manually annotated by BRENDA team
Sugiyama, S.; Ohtsuki, K.; Sato, K.; Kawabata, M.
Purification and characterization of six kiwifruit proteases isolated with two ion-exchange resins, Toyopearl-Super Q and Bakerbond WP-PEI
Biosci. Biotechnol. Biochem.
60
1994-2000
1996
Actinidia chinensis
-
Manually annotated by BRENDA team
Salih, E.; Malthouse, J.P.G.; Kowlessur, S.; Jarvis, M.; O'Driscoll, M.; Brocklehurst, K.
Differences in the chemical and catalytic characteristics of two crystallographically identical enzyme catalytic sites. Characterization of actinidin and papain by a combination of pH-dependent substrate catalysis kinetics and reactivity probe studies tar
Biochem. J.
247
181-193
1987
Actinidia chinensis
Manually annotated by BRENDA team
Kaneda, M.; Tomita, Y.; Tominaga, N.
Photochemical oxidation of actinidin, a thiol protease from Actinidia chinensis
Experientia
43
318-319
1987
Actinidia chinensis
-
Manually annotated by BRENDA team
Baker, E.N.
Comparison of the refined structures of two sulphhydryl proteases: actinidin and papain
Struct. Stud. Mol. Biol. Interest (Dodson, G. ; Glusker, J. P. ; Sayre, D. , eds. )
339-349
1981
Actinidia chinensis
-
Manually annotated by BRENDA team
Brocklehurst, K.; Baines, B.S.; Malthouse, J.P.G.
Differences in the interaction of the catalytic groups of the active centres of actinidin and papain. Rapid purification of fully active actinidin by covalent chromatography and characterization of its active centre by use of two-protonic-state reactivity probes
Biochem. J.
197
739-746
1981
Actinidia chinensis
Manually annotated by BRENDA team
Baker, E.N.; Boland, M.J.; Calder, P.C.; Hardman, M.J.
The specificity of actinidin and its relationship to the structure of the enzyme
Biochim. Biophys. Acta
616
30-34
1980
Actinidia chinensis
Manually annotated by BRENDA team
Baker, E.N.
Structure of actinidin after refinement at 1.7 A resolution
J. Mol. Biol.
141
441-484
1980
Actinidia chinensis
Manually annotated by BRENDA team
Carne, A.; Moore, C.H.
The amino acid sequence of the tryptic peptides from actinidin, a proteolytic enzyme from the fruit of Actinidia chinensis
Biochem. J.
173
73-83
1978
Actinidia chinensis
Manually annotated by BRENDA team
Boland, M.J.; Hardman, M.J.
The actinidin-catalysed hydrolysis of N-a-benzyloxycarbonyl-L-lysine p-nitrophenyl ester. pH dependence and mechanism
Eur. J. Biochem.
36
575-582
1973
Actinidia chinensis
Manually annotated by BRENDA team
McDowall, M.A.
The action of proteinase A 2 of Actinidia chinensis on the B-chain of oxidized insulin
Biochim. Biophys. Acta
293
226-231
1973
Actinidia chinensis
Manually annotated by BRENDA team
Baker, E.N.
Structure of actinidin: details of the polypeptide chain conformation and active site from an electron density map at 2-8 A resolution
J. Mol. Biol.
115
263-277
1977
Actinidia chinensis
Manually annotated by BRENDA team
Baker, E.N.
The structure of actinidin at 5-5 A resolution
J. Mol. Biol.
101
185-196
1976
Actinidia chinensis
Manually annotated by BRENDA team
Baker, E.N.
Preliminary crystallographic data for actinidin, a thiol protease from Actinidia chinensis
J. Mol. Biol.
74
411-412
1973
Actinidia chinensis
Manually annotated by BRENDA team
Boland, M.J.; Hardman, M.J.
Kinetic studies on the thiol protease from Actinidia chinensis
FEBS Lett.
27
282-284
1972
Actinidia chinensis
Manually annotated by BRENDA team
McDowall, M.A.
Anionic proteinase from Actinidia chinensis. Preparation and properties of the crystalline enzyme
Eur. J. Biochem.
14
214-221
1970
Actinidia chinensis
Manually annotated by BRENDA team
Auerswald, E.A.; Ngler, D.K.; Gross, S.; Assfalg-Machleidt, I.; Stubbs, M.T.; Eckerskorn, C.; Machleidt, W.; Fritz, H.
Hybrids of chicken cystatin with human kininogen domain 2 sequences exhibit novel inhibition of calpain, improved inhibition of actinidin and impaired inhibition of papain, cathepsin L and cathepsin B
Eur. J. Biochem.
235
534-542
1996
Actinidia chinensis
Manually annotated by BRENDA team
Lindahl, P.; Abrahamson, M.; Bjrk, I.
Interaction of recombinant human cystatin C with the cysteine proteinases papain and actinidin
Biochem. J.
281
49-55
1992
Actinidia chinensis
Manually annotated by BRENDA team
Reid, J.D.; Sreedharan, S.; Cole, A.; Maskell, S.; Bokth, A.; Thomas, E.W.; Brocklehurst, K.
Detection of a free enzyme isomerisation in actinidin catalysed hydrolysis
Biochem. Soc. Trans.
26
S173
1998
Actinidia chinensis
Manually annotated by BRENDA team
Tello-Solis, S.R.; Valle-Guadarrama, M.E.; Hernandez-Arana, A.
Purification and circular dichroism studies of multiple forms of actinidin from Actinidia chinensis (kiwifruit)
Plant Sci.
106
227-232
1995
Actinidia chinensis
-
Manually annotated by BRENDA team
Varughese, K.J.; Su, Y.; Cromwell, D.; Hasnain, S.; Xuong, N.
Crystal structure of an actinidin-E-64 complex
Biochemistry
31
5172-5176
1992
Actinidia chinensis
Manually annotated by BRENDA team
Pastorello, E.A.; Conti, A.; Pravettoni, V.; Farioli, L.; Rivolta, F.; Ansaloni, R.; Ispano, M.; Incorvais, C.; Giuffrida, M.G.; Ortolani, C.
Identification of actinidin as the major allergen of kiwi fruit
J. Allergy Clin. Immunol.
101
531-537
1998
Actinidia chinensis
Manually annotated by BRENDA team
Morimoto, K.; Kunii, S.; Hamano, K.; Tonomura, B.
Preparation and structural analysis of actinidain-processed atelocollagen of yellowfin tuna (Thunnus albacares)
Biosci. Biotechnol. Biochem.
68
861-867
2004
Actinidia deliciosa
Manually annotated by BRENDA team
Reid, J.D.; Hussain, S.; Bailey, T.S.; Sonkaria, S.; Sreedharan, S.K.; Thomas, E.W.; Resmini, M.; Brocklehurst, K.
Isomerization of the uncomplexed actinidin molecule: kinetic accessibility of additional steps in enzyme catalysis provided by solvent perturbation
Biochem. J.
378
699-703
2004
Actinidia chinensis
Manually annotated by BRENDA team
Gul, S.; Mellor, G.W.; Thomas, E.W.; Brocklehurst, K.
Temperature-dependences of the kinetics of reactions of papain and actinidin with a series of reactivity probes differing in key molecular recognition features
Biochem. J.
396
17-21
2006
Actinidia chinensis
Manually annotated by BRENDA team
Morimoto, K.; Furuta, E.; Hashimoto, H.; Inouye, K.
Effects of high concentration of salts on the esterase activity and structure of a kiwifruit peptidase, actinidain
J. Biochem.
139
1065-1071
2006
Actinidia deliciosa
Manually annotated by BRENDA team
Mostafaie, A.; Bidmeshkipour, A.; Shirvani, Z.; Mansouri, K.; Chalabi, M.
Kiwifruit actinidin: a proper new collagenase for isolation of cells from different tissues
Appl. Biochem. Biotechnol.
144
123-131
2008
Actinidia deliciosa, Actinidia deliciosa (A5HII1)
Manually annotated by BRENDA team
Lucas, J.S.; Nieuwenhuizen, N.J.; Atkinson, R.G.; Macrae, E.A.; Cochrane, S.A.; Warner, J.O.; Hourihane, J.O.
Kiwifruit allergy: actinidin is not a major allergen in the United Kingdom
Clin. Exp. Allergy
37
1340-1348
2007
Actinidia deliciosa
Manually annotated by BRENDA team
Lee, N.K.; Hahm, Y.T.
Isolation of cysteine protease actinidin gene from Chinese wild kiwifruit and its expression in Escherichia coli
Food Sci. Biotechnol.
16
294-298
2007
Actinidia chinensis (P00785)
-
Manually annotated by BRENDA team
Nieuwenhuizen, N.J.; Beuning, L.L.; Sutherland, P.W.; Sharma, N.N.; Cooney, J.M.; Bieleski, L.R.; Schroeder, R.; MacRae, E.A.; Atkinson, R.G.
Identification and characterisation of acidic and novel basic forms of actinidin, the highly abundant cysteine protease from kiwifruit
Funct. Plant Biol.
34
946-961
2007
Actinidia chinensis, Actinidia deliciosa
Manually annotated by BRENDA team
Stepek, G.; Lowe, A.E.; Buttle, D.J.; Duce, I.R.; Behnke, J.M.
In vitro and in vivo anthelmintic efficacy of plant cysteine proteinases against the rodent gastrointestinal nematode, Trichuris muris
Parasitology
132
681-689
2006
Actinidia chinensis
Manually annotated by BRENDA team
Palacin, A.; Rodriguez, J.; Blanco, C.; Lopez-Torrejon, G.; Sanchez-Monge, R.; Varela, J.; Jimenez, M.A.; Cumplido, J.; Carrillo, T.; Crespo, J.F.; Salcedo, G.
Immunoglobulin E recognition patterns to purified Kiwifruit (Actinidinia deliciosa) allergens in patients sensitized to Kiwi with different clinical symptoms
Clin. Exp. Allergy
38
1220-1228
2008
Actinidia deliciosa
Manually annotated by BRENDA team
Tuppo, L.; Giangrieco, I.; Palazzo, P.; Bernardi, M.L.; Scala, E.; Carratore, V.; Tamburrini, M.; Mari, A.; Ciardiello, M.A.
Kiwellin, a modular protein from green and gold kiwi fruits: evidence of in vivo and in vitro processing and IgE binding
J. Agric. Food Chem.
56
3812-3817
2008
Actinidia deliciosa
Manually annotated by BRENDA team
Oberhuber, C.; Bulley, S.M.; Ballmer-Weber, B.K.; Bublin, M.; Gaier, S.; DeWitt, A.M.; Briza, P.; Hofstetter, G.; Lidholm, J.; Vieths, S.; Hoffmann-Sommergruber, K.
Characterization of Bet v 1-related allergens from kiwifruit relevant for patients with combined kiwifruit and birch pollen allergy
Mol. Nutr. Food Res.
52 Suppl 2
S230-S240
2008
Actinidia chinensis (P00785)
Manually annotated by BRENDA team
Bublin, M.; Radauer, C.; Knulst, A.; Wagner, S.; Scheiner, O.; Mackie, A.R.; Mills, E.N.; Breiteneder, H.
Effects of gastrointestinal digestion and heating on the allergenicity of the kiwi allergens Act d 1, actinidin, and Act d 2, a thaumatin-like protein
Mol. Nutr. Food Res.
52
1130-1139
2008
Actinidia deliciosa
Manually annotated by BRENDA team
Bublin, M.; Pfister, M.; Radauer, C.; Oberhuber, C.; Bulley, S.; Dewitt, A.M.; Lidholm, J.; Reese, G.; Vieths, S.; Breiteneder, H.; Hoffmann-Sommergruber, K.; Ballmer-Weber, B.K.
Component-resolved diagnosis of kiwifruit allergy with purified natural and recombinant kiwifruit allergens
J. Allergy Clin. Immunol.
125; 687-94
694.e1
2010
Actinidia chinensis (P00785)
Manually annotated by BRENDA team
Morimoto, K.; Kawabata, K.; Kunii, S.; Hamano, K.; Saito, T.; Tonomura, B.
Characterization of type I collagen fibril formation using thioflavin T fluorescent dye
J. Biochem.
145
677-684
2009
Actinidia deliciosa
Manually annotated by BRENDA team
Kunii, S.; Morimoto, K.; Nagai, K.; Saito, T.; Sato, K.; Tonomura, B.
Actinidain-hydrolyzed type I collagen reveals a crucial amino acid sequence in fibril formation
J. Biol. Chem.
285
17465-17470
2010
Actinidia deliciosa
Manually annotated by BRENDA team
Aminlari, M.; Shekarforoush, S.S.; Gheisari, H.R.; Golestan, L.
Effect of actinidin on the protein solubility, water holding capacity, texture, electrophoretic pattern of beef, and on the quality attributes of a sausage product
J. Food Sci.
74
C221-C226
2009
Actinidia chinensis
Manually annotated by BRENDA team
Yogavel, M.; Nithya, N.; Suzuki, A.; Sugiyama, Y.; Yamane, T.; Velmurugan, D.; Sharma, A.
Structural analysis of actinidin and a comparison of cadmium and sulfur anomalous signals from actinidin crystals measured using in-house copper- and chromium-anode X-ray sources
Acta Crystallogr. Sect. D
66
1323-1333
2010
Actinidia arguta (A5HII2), Actinidia arguta
Manually annotated by BRENDA team
Grozdanovic, M.; Popovic, M.; Polovic, N.; Burazer, L.; Vuckovic, O.; Atanaskovic-Markovic, M.; Lindner, B.; Petersen, A.; Gavrovic-Jankulovic, M.
Evaluation of IgE reactivity of active and thermally inactivated actinidin, a biomarker of kiwifruit allergy
Food Chem. Toxicol.
50
1013-1018
2012
Actinidia deliciosa
Manually annotated by BRENDA team
Cavic, M.; Grozdanovic, M.; Bajic, A.; Srdic-Rajic, T.; Andus, P.R.; Gavrovic-Jankulovic, M.
Actinidin, a protease from kiwifruit, induces changes in morphology and adhesion of T84 intestinal epithelial cells
Phytochemistry
77
46-52
2012
Actinidia deliciosa
Manually annotated by BRENDA team
Nieuwenhuizen, N.J.; Maddumage, R.; Tsang, G.K.; Fraser, L.G.; Cooney, J.M.; De Silva, H.N.; Green, S.; Richardson, K.A.; Atkinson, R.G.
Mapping, complementation, and targets of the cysteine protease actinidin in kiwifruit
Plant Physiol.
158
376-388
2012
Actinidia chinensis, Actinidia deliciosa
Manually annotated by BRENDA team
Chalabi, M.; Khademi, F.; Yarani, R.; Mostafaie, A.
Proteolytic activities of kiwifruit actinidin (Actinidia deliciosa cv. Hayward) on different fibrous and globular proteins: a comparative study of actinidin with papain
Appl. Biochem. Biotechnol.
172
4025-4037
2014
Actinidia deliciosa, Actinidia deliciosa cv. Hayward
Manually annotated by BRENDA team
Grozdanovic, M.M.; Drakulic, B.J.; Gavrovic-Jankulovic, M.
Conformational mobility of active and E-64-inhibited actinidin
Biochim. Biophys. Acta
1830
4790-4799
2013
Actinidia deliciosa
Manually annotated by BRENDA team
Puglisi, I.; Petrone, G.; Lo Piero, A.
A kiwi juice aqueous solution as coagulant of bovine milk and its potential in Mozzarella cheese manufacture
Food Bioprod. Process.
92
67-72
2014
Actinidia deliciosa
-
Manually annotated by BRENDA team
Cavic, M.; Grozdanovic, M.M.; Bajic, A.; Jankovic, R.; Andjus, P.R.; Gavrovic-Jankulovic, M.
The effect of kiwifruit (Actinidia deliciosa) cysteine protease actinidin on the occludin tight junction network in T84 intestinal epithelial cells
Food Chem. Toxicol.
72
61-68
2014
Actinidia deliciosa
Manually annotated by BRENDA team
Homaei, A.; Etemadipour, R.
Improving the activity and stability of actinidin by immobilization on gold nanorods
Int. J. Biol. Macromol.
72
1176-1181
2015
Actinidia deliciosa
Manually annotated by BRENDA team
Dearman, R.J.; Beresford, L.; Foster, E.S.; McClain, S.; Kimber, I.
Characterization of the allergenic potential of proteins: an assessment of the kiwifruit allergen actinidin
J. Appl. Toxicol.
34
489-497
2014
Actinidia deliciosa
Manually annotated by BRENDA team
Grozdanovic, M.M.; Ostojic, S.; Aleksic, I.; Andjelkovic, U.; Petersen, A.; Gavrovic-Jankulovic, M.
Active actinidin retains function upon gastro-intestinal digestion and is more thermostable than the E-64-inhibited counterpart
J. Sci. Food Agric.
94
3046-3052
2014
Actinidia deliciosa
Manually annotated by BRENDA team
Mugita, N.; Nambu, T.; Takahashi, K.; Wang, P.L.; Komasa, Y.
Proteases, actinidin, papain and trypsin reduce oral biofilm on the tongue in elderly subjects and in vitro
Arch. Oral Biol.
82
233-240
2017
Actinidia chinensis (P00785)
Manually annotated by BRENDA team
Grozdanovic, M.M.; Cavic, M.; Nesic, A.; Andjelkovic, U.; Akbari, P.; Smit, J.J.; Gavrovic-Jankulovic, M.
Kiwifruit cysteine protease actinidin compromises the intestinal barrier by disrupting tight junctions
Biochim. Biophys. Acta
1860
516-526
2016
Actinidia deliciosa (A5HII1), Actinidia deliciosa
Manually annotated by BRENDA team
Martin, H.; Cordiner, S.B.; McGhie, T.K.
Kiwifruit actinidin digests salivary amylase but not gastric lipase
Food Funct.
8
3339-3345
2017
Actinidia deliciosa (A5HII1), Actinidia deliciosa
Manually annotated by BRENDA team
Ahmad, T.; Ismail, A.; Ahmad, S.; Khalil, K.; Teik Kee, L.; Awad, E.; Sazili, A.
Physicochemical characteristics and molecular structures of gelatin extracted from bovine skin effects of actinidin and papain enzymes pretreatment
Int. J. Food Prop.
22
138-153
2019
Actinidia deliciosa (A5HII1)
-
Manually annotated by BRENDA team
Zhu, X.; Kaur, L.; Boland, M.
Thermal inactivation of actinidin as affected by meat matrix
Meat Sci.
145
238-244
2018
Actinidia deliciosa (A5HII1), Actinidia deliciosa
Manually annotated by BRENDA team