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Information on EC 7.1.1.2 - NADH:ubiquinone reductase (H+-translocating)

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IUBMB Comments
A flavoprotein (FMN) containing iron-sulfur clusters. The complex is present in mitochondria and aerobic bacteria. Breakdown of the complex can release EC 1.6.99.3, NADH dehydrogenase. In photosynthetic bacteria, reversed electron transport through this enzyme can reduce NAD+ to NADH.
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Word Map
The expected taxonomic range for this enzyme is: Archaea, Bacteria, Eukaryota
Synonyms
complex i, complex 1, mitochondrial complex i, grim-19, respiratory complex i, respiratory chain complex i, nadh:ubiquinone oxidoreductase, mitochondrial nadh dehydrogenase, nadh-ubiquinone oxidoreductase, ndh-2, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
NADH + ubiquinone + 6 H+[side 1] = NAD+ + ubiquinol + 7 H+[side 2]
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