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Ligand 5'-adenylyl sulfate
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Basic Ligand Information
5'-adenylylsulfate, 5'-AMP sulfate, 5'-O-[hydroxy(sulfooxy)phosphoryl]adenosine, adenosine-5'-phosphosulfate, adenosine 5'-O-phosphosulfate, adenosine 5'-phosphate 5'-sulfate, adenosine 5'-phosphate sulfate, adenosine 5'-phosphosulfate, adenosine 5-phosphosulfate, adenylyl sulfate, adenylylsulfate
BRENDA
KEGG
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Show all BRENDA pathways known for 5'-adenylyl sulfate
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open all tablesRoles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (71 results)
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EC NUMBER 
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5'-adenylyl sulfate + thioredoxin = AMP + sulfite + thioredoxin disulfide
adenylyl sulfate + thioredoxin = AMP + sulfite + thioredoxin disulfide
adenylyl sulfate + glutathione = AMP + sulfite + glutathione disulfide
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adenylyl sulfate + cofactor sulfide = AMP + sulfite + cofactor disulfide
adenylyl sulfate + reduced acceptor = AMP + sulfite + acceptor
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
diphosphate + adenylyl sulfate = ATP + sulfate
diphosphate + adenylyl sulfate = ATP + sulfate
diphosphate + adenylyl sulfate = ATP + sulfate
diphosphate + adenylyl sulfate = ATP + sulfate
diphosphate + adenylyl sulfate = ATP + sulfate
diphosphate + adenylyl sulfate = ATP + sulfate
diphosphate + adenylyl sulfate = ATP + sulfate
diphosphate + adenylyl sulfate = ATP + sulfate
diphosphate + adenylyl sulfate = ATP + sulfate
diphosphate + adenylyl sulfate = ATP + sulfate
phosphate + adenosine 5'-phosphosulfate = ADP + SO42-
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In Vivo Product in Enzyme-catalyzed Reactions (21 results)
EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Substrate in Enzyme-catalyzed Reactions (194 results)
EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5'-adenylyl sulfate + glutathione = AMP + sulfite + glutathione disulfide
5'-adenylyl sulfate + reduced dithiothreitol = AMP + sulfite + oxidized dithiothreitol
5'-adenylyl sulfate + thioredoxin = AMP + sulfite + thioredoxin disulfide
adenosine 5'-phosphosulfate + thioredoxin = AMP + sulfite + thioredoxin disulfide
adenylyl sulfate + thioredoxin = AMP + sulfite + thioredoxin disulfide
adenosine 5'-phosphosulfate + thioredoxin = AMP + sulfite + oxidized thioredoxin
adenosine 5'-phosphosulfate + thioredoxin I = AMP + sulfite + oxidized thioredoxin I
5'-adenylyl sulfate + glutathione = AMP + sulfite + glutathione disulfide
-
5'-adenylylsulfate + dithioerythritol = adenosine 5'-monophosphate + sulfite + oxidized dithioerythritol
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5'-adenylylsulfate + dithiothreitol = adenosine 5'-monophosphate + sulfite + oxidized dithiothreitol
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5'-adenylylsulfate + glutathione + glutathione = adenosine monophosphate + sulfite + oxidized glutathione
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5'-adenylylsulfate + glutathione = adenosine monophosphate + sulfite + oxidized glutathione
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adenylyl sulfate + glutathione = AMP + sulfite + glutathione disulfide
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5'-adenylylsulfate + dithioerythritol = adenosine 5'-monophosphate + sulfite + oxidized dithioerythritol
5'-adenylylsulfate + dithiothreitol = adenosine 5'-monophosphate + sulfite + oxidized dithiothreitol
adenylyl sulfate + cofactor sulfide = AMP + sulfite + cofactor disulfide
adenylyl sulfate + dithioerythritol = AMP + sulfite + ?
adenylyl sulfate + dithioerythritol = AMP + sulfite + oxidized dithioerythritol
adenylyl sulfate + ferrocytochrome c3 = AMP + sulfite + ferricytochrome
adenylyl sulfate + reduced acceptor = AMP + sulfite + acceptor
adenylyl sulfate + reduced glutaredoxin 1 = AMP + sulfite + oxidized glutaredoxin 1
adenylyl sulfate + reduced methyl viologen = AMP + sulfite + methyl viologen
adenylyl sulfate + reduced riboflavin = AMP + sulfite + oxidized riboflavin
adenylyl sulfate + reduced thioredoxin 1 = AMP + sulfite + oxidized thioredoxin 1
adenylyl sulfate + reduced thioredoxin = AMP + sulfite + oxidized thioredoxin
adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenosine 5'-phosphosulfate + ADP
adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenosine 5'-phosphosulfate + ADP
adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenosine 5'-phosphosulfate + ADP
adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenosine 5'-phosphosulfate + ADP
adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenosine 5'-phosphosulfate + ADP
adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenosine 5'-phosphosulfate + ADP
adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenosine 5'-phosphosulfate + ADP
adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenosine 5'-phosphosulfate + ADP
adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenosine 5'-phosphosulfate + ADP
adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenosine 5'-phosphosulfate + ADP
adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenosine 5'-phosphosulfate + ADP
adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenosine 5'-phosphosulfate + ADP
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
MgATP2- + adenosine 5'-phosphosulfate = MgADP- + 3'-phosphoadenosine 5'-phosphosulfate
MgATP2- + adenosine 5'-phosphosulfate = MgADP- + 3'-phosphoadenosine 5'-phosphosulfate
MgATP2- + adenosine 5'-phosphosulfate = MgADP- + 3'-phosphoadenosine 5'-phosphosulfate
MgATP2- + adenosine 5'-phosphosulfate = MgADP- + 3'-phosphoadenosine 5'-phosphosulfate
MgATP2- + adenosine 5'-phosphosulfate = MgADP- + 3'-phosphoadenosine 5'-phosphosulfate
MgATP2- + adenosine 5'-phosphosulfate = MgADP- + 3'-phosphoadenosine 5'-phosphosulfate
MgATP2- + adenosine 5'-phosphosulfate = MgADP- + 3'-phosphoadenosine 5'-phosphosulfate
MgATP2- + adenosine 5'-phosphosulfate = MgADP- + 3'-phosphoadenosine 5'-phosphosulfate
MgATP2- + adenosine 5'-phosphosulfate = MgADP- + 3'-phosphoadenosine 5'-phosphosulfate
MgATP2- + adenosine 5'-phosphosulfate = MgADP- + 3'-phosphoadenosine 5'-phosphosulfate
MgATP2- + adenosine 5'-phosphosulfate = MgADP- + 3'-phosphoadenosine 5'-phosphosulfate
MgATP2- + adenosine 5'-phosphosulfate = MgADP- + 3'-phosphoadenosine 5'-phosphosulfate
adenosine 5'-O-(3-thiotriphosphate) + adenosine 5-phosphosulfate = ADP + 3'-thiophosphoadenosine 5'-phosphosulfate
adenosine 5'-O-(3-thiotriphosphate) + adenosine 5-phosphosulfate = ADP + 3'-thiophosphoadenosine 5'-phosphosulfate
adenosine 5'-O-(3-thiotriphosphate) + adenosine 5-phosphosulfate = ADP + 3'-thiophosphoadenosine 5'-phosphosulfate
adenosine 5'-O-(3-thiotriphosphate) + adenosine 5-phosphosulfate = ADP + 3'-thiophosphoadenosine 5'-phosphosulfate
adenosine 5'-O-(3-thiotriphosphate) + adenosine 5-phosphosulfate = ADP + 3'-thiophosphoadenosine 5'-phosphosulfate
adenosine 5'-O-(3-thiotriphosphate) + adenosine 5-phosphosulfate = ADP + 3'-thiophosphoadenosine 5'-phosphosulfate
adenosine 5'-O-(3-thiotriphosphate) + adenosine 5-phosphosulfate = ADP + 3'-thiophosphoadenosine 5'-phosphosulfate
adenosine 5'-O-(3-thiotriphosphate) + adenosine 5-phosphosulfate = ADP + 3'-thiophosphoadenosine 5'-phosphosulfate
adenosine 5'-O-(3-thiotriphosphate) + adenosine 5-phosphosulfate = ADP + 3'-thiophosphoadenosine 5'-phosphosulfate
adenosine 5'-O-(3-thiotriphosphate) + adenosine 5-phosphosulfate = ADP + 3'-thiophosphoadenosine 5'-phosphosulfate
adenosine 5'-O-(3-thiotriphosphate) + adenosine 5-phosphosulfate = ADP + 3'-thiophosphoadenosine 5'-phosphosulfate
adenosine 5'-O-(3-thiotriphosphate) + adenosine 5-phosphosulfate = ADP + 3'-thiophosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine 5-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
CTP + adenosine 5-phosphosulfate = CDP + 3'-phosphoadenosine 5'-phosphosulfate
CTP + adenosine 5-phosphosulfate = CDP + 3'-phosphoadenosine 5'-phosphosulfate
CTP + adenosine 5-phosphosulfate = CDP + 3'-phosphoadenosine 5'-phosphosulfate
CTP + adenosine 5-phosphosulfate = CDP + 3'-phosphoadenosine 5'-phosphosulfate
CTP + adenosine 5-phosphosulfate = CDP + 3'-phosphoadenosine 5'-phosphosulfate
CTP + adenosine 5-phosphosulfate = CDP + 3'-phosphoadenosine 5'-phosphosulfate
CTP + adenosine 5-phosphosulfate = CDP + 3'-phosphoadenosine 5'-phosphosulfate
CTP + adenosine 5-phosphosulfate = CDP + 3'-phosphoadenosine 5'-phosphosulfate
CTP + adenosine 5-phosphosulfate = CDP + 3'-phosphoadenosine 5'-phosphosulfate
CTP + adenosine 5-phosphosulfate = CDP + 3'-phosphoadenosine 5'-phosphosulfate
CTP + adenosine 5-phosphosulfate = CDP + 3'-phosphoadenosine 5'-phosphosulfate
CTP + adenosine 5-phosphosulfate = CDP + 3'-phosphoadenosine 5'-phosphosulfate
dATP + adenosine 5-phosphosulfate = dADP + 3'-phosphoadenosine 5'-phosphosulfate
dATP + adenosine 5-phosphosulfate = dADP + 3'-phosphoadenosine 5'-phosphosulfate
dATP + adenosine 5-phosphosulfate = dADP + 3'-phosphoadenosine 5'-phosphosulfate
dATP + adenosine 5-phosphosulfate = dADP + 3'-phosphoadenosine 5'-phosphosulfate
dATP + adenosine 5-phosphosulfate = dADP + 3'-phosphoadenosine 5'-phosphosulfate
dATP + adenosine 5-phosphosulfate = dADP + 3'-phosphoadenosine 5'-phosphosulfate
dATP + adenosine 5-phosphosulfate = dADP + 3'-phosphoadenosine 5'-phosphosulfate
dATP + adenosine 5-phosphosulfate = dADP + 3'-phosphoadenosine 5'-phosphosulfate
dATP + adenosine 5-phosphosulfate = dADP + 3'-phosphoadenosine 5'-phosphosulfate
dATP + adenosine 5-phosphosulfate = dADP + 3'-phosphoadenosine 5'-phosphosulfate
dATP + adenosine 5-phosphosulfate = dADP + 3'-phosphoadenosine 5'-phosphosulfate
dATP + adenosine 5-phosphosulfate = dADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenosine-5'-phosphosulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate
ATP + adenylyl sulfate = ADP + 3'-phosphoadenylyl sulfate
ATP + adenylyl sulfate = ADP + 3'-phosphoadenylyl sulfate
ATP + adenylyl sulfate = ADP + 3'-phosphoadenylyl sulfate
ATP + adenylyl sulfate = ADP + 3'-phosphoadenylyl sulfate
ATP + adenylyl sulfate = ADP + 3'-phosphoadenylyl sulfate
ATP + adenylyl sulfate = ADP + 3'-phosphoadenylyl sulfate
ATP + adenylyl sulfate = ADP + 3'-phosphoadenylyl sulfate
ATP + adenylyl sulfate = ADP + 3'-phosphoadenylyl sulfate
ATP + adenylyl sulfate = ADP + 3'-phosphoadenylyl sulfate
ATP + adenylyl sulfate = ADP + 3'-phosphoadenylyl sulfate
ATP + adenylyl sulfate = ADP + 3'-phosphoadenylyl sulfate
ATP + adenylyl sulfate = ADP + 3'-phosphoadenylyl sulfate
MgATP2- + adenylyl sulfate = MgADP- + 3'-phosphoadenylyl sulfate
MgATP2- + adenylyl sulfate = MgADP- + 3'-phosphoadenylyl sulfate
MgATP2- + adenylyl sulfate = MgADP- + 3'-phosphoadenylyl sulfate
MgATP2- + adenylyl sulfate = MgADP- + 3'-phosphoadenylyl sulfate
MgATP2- + adenylyl sulfate = MgADP- + 3'-phosphoadenylyl sulfate
MgATP2- + adenylyl sulfate = MgADP- + 3'-phosphoadenylyl sulfate
MgATP2- + adenylyl sulfate = MgADP- + 3'-phosphoadenylyl sulfate
MgATP2- + adenylyl sulfate = MgADP- + 3'-phosphoadenylyl sulfate
MgATP2- + adenylyl sulfate = MgADP- + 3'-phosphoadenylyl sulfate
MgATP2- + adenylyl sulfate = MgADP- + 3'-phosphoadenylyl sulfate
MgATP2- + adenylyl sulfate = MgADP- + 3'-phosphoadenylyl sulfate
MgATP2- + adenylyl sulfate = MgADP- + 3'-phosphoadenylyl sulfate
diphosphate + adenylyl sulfate = ATP + sulfate
diphosphate + adenylyl sulfate = ATP + sulfate
diphosphate + adenylyl sulfate = ATP + sulfate
diphosphate + adenylyl sulfate = ATP + sulfate
diphosphate + adenylyl sulfate = ATP + sulfate
diphosphate + adenylyl sulfate = ATP + sulfate
diphosphate + adenylyl sulfate = ATP + sulfate
diphosphate + adenylyl sulfate = ATP + sulfate
diphosphate + adenylyl sulfate = ATP + sulfate
diphosphate + adenylyl sulfate = ATP + sulfate
phosphate + adenosine 5'-phosphosulfate = ADP + SO42-
-
adenylylsulfate + NH3 = adenosine 5'-phosphoramidate + sulfate
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Product in Enzyme-catalyzed Reactions (74 results)
EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + sulfate = diphosphate + adenylylsulfate
643252, 0, 643283, 641225, 643261, 643277, 643287, 643293, 641204, 643258, 643259, 643263, 641219, 643269, 643271, 643290, 643278, 643292, 643276, 641208, 643264, 643266, 643267, 643268, 643288, 643281, 643282, 643279, 393950, 643255, 643284, 643274, 643254, 643273, 643294, 643272, 643275, 643291, 643260, 643253, 643280, 643286, 643285, 643289, 643295, 643270
ATP + sulfate = diphosphate + adenylylsulfate
643252, 0, 643283, 641225, 643261, 643277, 643287, 643293, 641204, 643258, 643259, 643263, 641219, 643269, 643271, 643290, 643278, 643292, 643276, 641208, 643264, 643266, 643267, 643268, 643288, 643281, 643282, 643279, 393950, 643255, 643284, 643274, 643254, 643273, 643294, 643272, 643275, 643291, 643260, 643253, 643280, 643286, 643285, 643289, 643295, 643270
ATP + sulfate = diphosphate + adenylylsulfate
643252, 0, 643283, 641225, 643261, 643277, 643287, 643293, 641204, 643258, 643259, 643263, 641219, 643269, 643271, 643290, 643278, 643292, 643276, 641208, 643264, 643266, 643267, 643268, 643288, 643281, 643282, 643279, 393950, 643255, 643284, 643274, 643254, 643273, 643294, 643272, 643275, 643291, 643260, 643253, 643280, 643286, 643285, 643289, 643295, 643270
ATP + sulfate = diphosphate + adenylylsulfate
643252, 0, 643283, 641225, 643261, 643277, 643287, 643293, 641204, 643258, 643259, 643263, 641219, 643269, 643271, 643290, 643278, 643292, 643276, 641208, 643264, 643266, 643267, 643268, 643288, 643281, 643282, 643279, 393950, 643255, 643284, 643274, 643254, 643273, 643294, 643272, 643275, 643291, 643260, 643253, 643280, 643286, 643285, 643289, 643295, 643270
ATP + sulfate = diphosphate + adenylylsulfate
643252, 0, 643283, 641225, 643261, 643277, 643287, 643293, 641204, 643258, 643259, 643263, 641219, 643269, 643271, 643290, 643278, 643292, 643276, 641208, 643264, 643266, 643267, 643268, 643288, 643281, 643282, 643279, 393950, 643255, 643284, 643274, 643254, 643273, 643294, 643272, 643275, 643291, 643260, 643253, 643280, 643286, 643285, 643289, 643295, 643270
ATP + sulfate = diphosphate + adenylylsulfate
643252, 0, 643283, 641225, 643261, 643277, 643287, 643293, 641204, 643258, 643259, 643263, 641219, 643269, 643271, 643290, 643278, 643292, 643276, 641208, 643264, 643266, 643267, 643268, 643288, 643281, 643282, 643279, 393950, 643255, 643284, 643274, 643254, 643273, 643294, 643272, 643275, 643291, 643260, 643253, 643280, 643286, 643285, 643289, 643295, 643270
ATP + sulfate = diphosphate + adenylylsulfate
643252, 0, 643283, 641225, 643261, 643277, 643287, 643293, 641204, 643258, 643259, 643263, 641219, 643269, 643271, 643290, 643278, 643292, 643276, 641208, 643264, 643266, 643267, 643268, 643288, 643281, 643282, 643279, 393950, 643255, 643284, 643274, 643254, 643273, 643294, 643272, 643275, 643291, 643260, 643253, 643280, 643286, 643285, 643289, 643295, 643270
ATP + sulfate = diphosphate + adenylylsulfate
643252, 0, 643283, 641225, 643261, 643277, 643287, 643293, 641204, 643258, 643259, 643263, 641219, 643269, 643271, 643290, 643278, 643292, 643276, 641208, 643264, 643266, 643267, 643268, 643288, 643281, 643282, 643279, 393950, 643255, 643284, 643274, 643254, 643273, 643294, 643272, 643275, 643291, 643260, 643253, 643280, 643286, 643285, 643289, 643295, 643270
ATP + sulfate = diphosphate + adenylylsulfate
643252, 0, 643283, 641225, 643261, 643277, 643287, 643293, 641204, 643258, 643259, 643263, 641219, 643269, 643271, 643290, 643278, 643292, 643276, 641208, 643264, 643266, 643267, 643268, 643288, 643281, 643282, 643279, 393950, 643255, 643284, 643274, 643254, 643273, 643294, 643272, 643275, 643291, 643260, 643253, 643280, 643286, 643285, 643289, 643295, 643270
ATP + sulfate = diphosphate + adenylylsulfate
643252, 0, 643283, 641225, 643261, 643277, 643287, 643293, 641204, 643258, 643259, 643263, 641219, 643269, 643271, 643290, 643278, 643292, 643276, 641208, 643264, 643266, 643267, 643268, 643288, 643281, 643282, 643279, 393950, 643255, 643284, 643274, 643254, 643273, 643294, 643272, 643275, 643291, 643260, 643253, 643280, 643286, 643285, 643289, 643295, 643270
3'-phosphoadenosine 5'-phosphosulfate + H2O = adenosine 5'-phosphosulfate + phosphate
-
adenosine 3'-phosphate 5'-phosphosulfate + H2O = adenosine 5'-phosphosulfate + phosphate
-
Activator in Enzyme-catalyzed Reactions (2 results)
EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
Inhibitor in Enzyme-catalyzed Reactions (248 results)
EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
when thioredoxin concentrations are limiting, elevated concentrations of APS result in inhibition
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adenosine 5'-phosphosulfate can bind to E-MgADP forming a catalytically inactive E-MgADP-APS ternary complex
adenosine 5'-phosphosulfate can bind to E-MgADP forming a catalytically inactive E-MgADP-APS ternary complex
adenosine 5'-phosphosulfate can bind to E-MgADP forming a catalytically inactive E-MgADP-APS ternary complex
adenosine 5'-phosphosulfate can bind to E-MgADP forming a catalytically inactive E-MgADP-APS ternary complex
adenosine 5'-phosphosulfate can bind to E-MgADP forming a catalytically inactive E-MgADP-APS ternary complex
adenosine 5'-phosphosulfate can bind to E-MgADP forming a catalytically inactive E-MgADP-APS ternary complex
adenosine 5'-phosphosulfate can bind to E-MgADP forming a catalytically inactive E-MgADP-APS ternary complex
adenosine 5'-phosphosulfate can bind to E-MgADP forming a catalytically inactive E-MgADP-APS ternary complex
adenosine 5'-phosphosulfate can bind to E-MgADP forming a catalytically inactive E-MgADP-APS ternary complex
adenosine 5'-phosphosulfate can bind to E-MgADP forming a catalytically inactive E-MgADP-APS ternary complex
adenosine 5'-phosphosulfate can bind to E-MgADP forming a catalytically inactive E-MgADP-APS ternary complex
adenosine 5'-phosphosulfate can bind to E-MgADP forming a catalytically inactive E-MgADP-APS ternary complex
adenylyl sulfate acts as a strong uncompetitive inhibitor of the APS kinase reaction
adenylyl sulfate acts as a strong uncompetitive inhibitor of the APS kinase reaction
adenylyl sulfate acts as a strong uncompetitive inhibitor of the APS kinase reaction
adenylyl sulfate acts as a strong uncompetitive inhibitor of the APS kinase reaction
adenylyl sulfate acts as a strong uncompetitive inhibitor of the APS kinase reaction
adenylyl sulfate acts as a strong uncompetitive inhibitor of the APS kinase reaction
adenylyl sulfate acts as a strong uncompetitive inhibitor of the APS kinase reaction
adenylyl sulfate acts as a strong uncompetitive inhibitor of the APS kinase reaction
adenylyl sulfate acts as a strong uncompetitive inhibitor of the APS kinase reaction
adenylyl sulfate acts as a strong uncompetitive inhibitor of the APS kinase reaction
adenylyl sulfate acts as a strong uncompetitive inhibitor of the APS kinase reaction
adenylyl sulfate acts as a strong uncompetitive inhibitor of the APS kinase reaction
potent product inhibition, competitive with both MgATP2- and MoO42- in molybdolysis assay
potent product inhibition, competitive with both MgATP2- and MoO42- in molybdolysis assay
potent product inhibition, competitive with both MgATP2- and MoO42- in molybdolysis assay
potent product inhibition, competitive with both MgATP2- and MoO42- in molybdolysis assay
potent product inhibition, competitive with both MgATP2- and MoO42- in molybdolysis assay
potent product inhibition, competitive with both MgATP2- and MoO42- in molybdolysis assay
potent product inhibition, competitive with both MgATP2- and MoO42- in molybdolysis assay
potent product inhibition, competitive with both MgATP2- and MoO42- in molybdolysis assay
potent product inhibition, competitive with both MgATP2- and MoO42- in molybdolysis assay
potent product inhibition, competitive with both MgATP2- and MoO42- in molybdolysis assay
potent product inhibitor, competitive with respect to MgATP2-, and a mixed type inhibitor with respect to molybdate
potent product inhibitor, competitive with respect to MgATP2-, and a mixed type inhibitor with respect to molybdate
potent product inhibitor, competitive with respect to MgATP2-, and a mixed type inhibitor with respect to molybdate
potent product inhibitor, competitive with respect to MgATP2-, and a mixed type inhibitor with respect to molybdate
potent product inhibitor, competitive with respect to MgATP2-, and a mixed type inhibitor with respect to molybdate
potent product inhibitor, competitive with respect to MgATP2-, and a mixed type inhibitor with respect to molybdate
potent product inhibitor, competitive with respect to MgATP2-, and a mixed type inhibitor with respect to molybdate
potent product inhibitor, competitive with respect to MgATP2-, and a mixed type inhibitor with respect to molybdate
potent product inhibitor, competitive with respect to MgATP2-, and a mixed type inhibitor with respect to molybdate
potent product inhibitor, competitive with respect to MgATP2-, and a mixed type inhibitor with respect to molybdate
APS, binding mode, overview. On the ATP sulfurylase domain that initially produces APS from sulfate and ATP, APS acts as a potent product inhibitor, being competitive with both ATP and sulfate. For the APS kinase domain that phosphorylates APS to PAPS, APS is an uncompetitive substrate inhibitor that can bind both at the ATP/ADP-binding site and the PAPS/APS-binding site; APS, binding mode, overview. On the ATP sulfurylase domain that initially produces APS from sulfate and ATP, APS acts as a potent product inhibitor, being competitive with both ATP and sulfate. For the APS kinase domain that phosphorylates APS to PAPS, APS is an uncompetitive substrate inhibitor that can bind both at the ATP/ADP-binding site and the PAPS/APS-binding site
APS, binding mode, overview. On the ATP sulfurylase domain that initially produces APS from sulfate and ATP, APS acts as a potent product inhibitor, being competitive with both ATP and sulfate. For the APS kinase domain that phosphorylates APS to PAPS, APS is an uncompetitive substrate inhibitor that can bind both at the ATP/ADP-binding site and the PAPS/APS-binding site; APS, binding mode, overview. On the ATP sulfurylase domain that initially produces APS from sulfate and ATP, APS acts as a potent product inhibitor, being competitive with both ATP and sulfate. For the APS kinase domain that phosphorylates APS to PAPS, APS is an uncompetitive substrate inhibitor that can bind both at the ATP/ADP-binding site and the PAPS/APS-binding site
APS, binding mode, overview. On the ATP sulfurylase domain that initially produces APS from sulfate and ATP, APS acts as a potent product inhibitor, being competitive with both ATP and sulfate. For the APS kinase domain that phosphorylates APS to PAPS, APS is an uncompetitive substrate inhibitor that can bind both at the ATP/ADP-binding site and the PAPS/APS-binding site; APS, binding mode, overview. On the ATP sulfurylase domain that initially produces APS from sulfate and ATP, APS acts as a potent product inhibitor, being competitive with both ATP and sulfate. For the APS kinase domain that phosphorylates APS to PAPS, APS is an uncompetitive substrate inhibitor that can bind both at the ATP/ADP-binding site and the PAPS/APS-binding site
APS, binding mode, overview. On the ATP sulfurylase domain that initially produces APS from sulfate and ATP, APS acts as a potent product inhibitor, being competitive with both ATP and sulfate. For the APS kinase domain that phosphorylates APS to PAPS, APS is an uncompetitive substrate inhibitor that can bind both at the ATP/ADP-binding site and the PAPS/APS-binding site; APS, binding mode, overview. On the ATP sulfurylase domain that initially produces APS from sulfate and ATP, APS acts as a potent product inhibitor, being competitive with both ATP and sulfate. For the APS kinase domain that phosphorylates APS to PAPS, APS is an uncompetitive substrate inhibitor that can bind both at the ATP/ADP-binding site and the PAPS/APS-binding site
APS, binding mode, overview. On the ATP sulfurylase domain that initially produces APS from sulfate and ATP, APS acts as a potent product inhibitor, being competitive with both ATP and sulfate. For the APS kinase domain that phosphorylates APS to PAPS, APS is an uncompetitive substrate inhibitor that can bind both at the ATP/ADP-binding site and the PAPS/APS-binding site; APS, binding mode, overview. On the ATP sulfurylase domain that initially produces APS from sulfate and ATP, APS acts as a potent product inhibitor, being competitive with both ATP and sulfate. For the APS kinase domain that phosphorylates APS to PAPS, APS is an uncompetitive substrate inhibitor that can bind both at the ATP/ADP-binding site and the PAPS/APS-binding site
APS, binding mode, overview. On the ATP sulfurylase domain that initially produces APS from sulfate and ATP, APS acts as a potent product inhibitor, being competitive with both ATP and sulfate. For the APS kinase domain that phosphorylates APS to PAPS, APS is an uncompetitive substrate inhibitor that can bind both at the ATP/ADP-binding site and the PAPS/APS-binding site; APS, binding mode, overview. On the ATP sulfurylase domain that initially produces APS from sulfate and ATP, APS acts as a potent product inhibitor, being competitive with both ATP and sulfate. For the APS kinase domain that phosphorylates APS to PAPS, APS is an uncompetitive substrate inhibitor that can bind both at the ATP/ADP-binding site and the PAPS/APS-binding site
APS, binding mode, overview. On the ATP sulfurylase domain that initially produces APS from sulfate and ATP, APS acts as a potent product inhibitor, being competitive with both ATP and sulfate. For the APS kinase domain that phosphorylates APS to PAPS, APS is an uncompetitive substrate inhibitor that can bind both at the ATP/ADP-binding site and the PAPS/APS-binding site; APS, binding mode, overview. On the ATP sulfurylase domain that initially produces APS from sulfate and ATP, APS acts as a potent product inhibitor, being competitive with both ATP and sulfate. For the APS kinase domain that phosphorylates APS to PAPS, APS is an uncompetitive substrate inhibitor that can bind both at the ATP/ADP-binding site and the PAPS/APS-binding site
APS, binding mode, overview. On the ATP sulfurylase domain that initially produces APS from sulfate and ATP, APS acts as a potent product inhibitor, being competitive with both ATP and sulfate. For the APS kinase domain that phosphorylates APS to PAPS, APS is an uncompetitive substrate inhibitor that can bind both at the ATP/ADP-binding site and the PAPS/APS-binding site; APS, binding mode, overview. On the ATP sulfurylase domain that initially produces APS from sulfate and ATP, APS acts as a potent product inhibitor, being competitive with both ATP and sulfate. For the APS kinase domain that phosphorylates APS to PAPS, APS is an uncompetitive substrate inhibitor that can bind both at the ATP/ADP-binding site and the PAPS/APS-binding site
APS, binding mode, overview. On the ATP sulfurylase domain that initially produces APS from sulfate and ATP, APS acts as a potent product inhibitor, being competitive with both ATP and sulfate. For the APS kinase domain that phosphorylates APS to PAPS, APS is an uncompetitive substrate inhibitor that can bind both at the ATP/ADP-binding site and the PAPS/APS-binding site; APS, binding mode, overview. On the ATP sulfurylase domain that initially produces APS from sulfate and ATP, APS acts as a potent product inhibitor, being competitive with both ATP and sulfate. For the APS kinase domain that phosphorylates APS to PAPS, APS is an uncompetitive substrate inhibitor that can bind both at the ATP/ADP-binding site and the PAPS/APS-binding site
APS, binding mode, overview. On the ATP sulfurylase domain that initially produces APS from sulfate and ATP, APS acts as a potent product inhibitor, being competitive with both ATP and sulfate. For the APS kinase domain that phosphorylates APS to PAPS, APS is an uncompetitive substrate inhibitor that can bind both at the ATP/ADP-binding site and the PAPS/APS-binding site; APS, binding mode, overview. On the ATP sulfurylase domain that initially produces APS from sulfate and ATP, APS acts as a potent product inhibitor, being competitive with both ATP and sulfate. For the APS kinase domain that phosphorylates APS to PAPS, APS is an uncompetitive substrate inhibitor that can bind both at the ATP/ADP-binding site and the PAPS/APS-binding site
3D Structure of Enzyme-Ligand-Complex (PDB) (267 results)
EC NUMBER
ENZYME 3D STRUCTURE
Enzyme Kinetic Parameters
kcat Value (Turnover Number) (43 results)
EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.015
-
mutant D122G, pH not specified in the publication, temperature not specified in the publication
0.333
-
wild-type, pH not specified in the publication, temperature not specified in the publication
3.4
-
recombinant enzyme lacking transit peptide, artificial reductant dithiothreitol
0.153
-
assay conditions: APS reductase (0.00021 mM), PK (8.4 units/ml), LDH (18.0 units/ml), adenylate kinase (10 units/ml), thioredoxin (0.0373 mM), MgCl2 (3.0 mM), DTT (2.0 mM), ATP (1.0 mM), PEP (1.0 mM), EDTA (1.0 mM), GSH (5.0 mM), NADH (0.030 mM), and Hepes (50 mM, pH 8.0), at 25รยฐC
0.315
-
deletion mutant lacking the first 34 amino acids of the N-terminus, delta34N
2.6
-
in 0.1 M HEPES/KOH buffer (pH 6.8), 0.1 M potassium phosphate (pH 6.8), 0.1 M KH2PO4 (pH 4.2), at 30รยฐC
3
6
in 0.1 M HEPES/KOH buffer (pH 6.8), 0.1 M potassium phosphate (pH 6.8), 0.1 M KH2PO4 (pH 4.2), at 30รยฐC
KM Value (126 results)
EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0025
-
recombinant enzyme lacking transit peptide, artificial reductand glutathione
0.0038
-
recombinant enzyme lacking transit peptide, artificial reductand dithiothreitol
0.0058
-
mutant D122G, pH not specified in the publication, temperature not specified in the publication
0.0069
-
wild-type, pH not specified in the publication, temperature not specified in the publication
0.00057
-
assay conditions: APS reductase (0.00021 mM), PK (8.4 units/ml), LDH (18.0 units/ml), adenylate kinase (10 units/ml), thioredoxin (0.0373 mM), MgCl2 (3.0 mM), DTT (2.0 mM), ATP (1.0 mM), PEP (1.0 mM), EDTA (1.0 mM), GSH (5.0 mM), NADH (0.030 mM), and Hepes (50 mM, pH 8.0), at 25รยฐC
0.002
-
value is below 0.002 for a deletion mutant lacking the first 34 amino acids of the N-terminus, delta34N
0.0046
-
deletion mutant lacking the first 50 amino acids of the N-terminus, delta50N
1
-
in 0.1 M HEPES/KOH buffer (pH 6.8), 0.1 M potassium phosphate (pH 6.8), 0.1 M KH2PO4 (pH 4.2), at 30รยฐC
26
-
in 0.1 M HEPES/KOH buffer (pH 6.8), 0.1 M potassium phosphate (pH 6.8), 0.1 M KH2PO4 (pH 4.2), at 30รยฐC
Ki Value (31 results)
EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
-999
-
no inhibition of a deletion mutant lacking the first 50 amino acids of the N-terminus, delta50N
0.029
-
deletion mutant lacking the first 34 amino acids of the N-terminus, delta34N