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2-dehydro-D-gulonate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+
-
2-dehydro-L-gulonate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+
-
2-dehydro-D-gluconate + 2,6-dichlorophenolindophenol = 2,5-didehydro-D-gluconate + ?
-
2-dehydro-D-gluconate + ferricyanide = 2,5-didehydro-D-gluconate + ferrocyanide
-
2-dehydro-D-gluconate + methylene blue = 2,5-didehydro-D-gluconate + ?
-
2-dehydro-D-gluconate + nitro blue tetrazolium = 2,5-didehydro-D-gluconate + ?
-
2-dehydro-D-gluconate + phenazine methosulfate = 2,5-didehydro-D-gluconate + ?
-
2-dehydro-D-gluconate + pyocyanine = 2,5-didehydro-D-gluconate + ?
-
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0.0123
-
isoenzyme A, F22Y mutant enzyme
0.0312
-
isoenzyme A, wild-type
0.39
-
F22Y/K232G/R235T/R238H/A272G isoenzyme A mutant
7.2
-
F22Y/A272G isoenzyme A mutant
8.7
-
F22Y/K232G/R235T/R238H/A272G isoenzyme A mutant
9.1
-
F22Y/K232G/R238H/A272G isoenzyme A mutant
13
-
F22Y/K232G/R235G/R238E/A272G isoenzyme A mutant
13
-
K232G/R238H isoenzyme A mutant
27
-
F22Y/S232T/R235S/R238H/A272G isoenzyme A mutant
30
-
F22Y/A272G isoenzyme A mutant
32
-
F22Y/K232G/R235G/R238H/A272G isoenzyme A mutant
32
-
F22Y/K232G/R238H/A272G isoenzyme A mutant
43
-
F22Y/K232G/R235G/R238H/A272G isoenzyme A mutant
110
-
K232G/R238H isoenzyme A mutant
130
-
isoenzyme A, wild-type
150
-
F22Y/K232G/R235T/R238E/A272G isoenzyme A mutant
1.8
-
isoform 2,5-diketo-D-gluconate reductase I, at pH 7.0 and 30°C
13.5
-
isoform 2,5-diketo-D-gluconate reductase II, at pH 7.0 and 30°C
19.78
-
at pH 6.4 and 25°C
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Purification and characterization of the 2-ketoaldonate reductase from Brevibacterium ketosoreductum ATCC21914
1998
Yum, D-Y.; Bae, S-S.; Pan, J-G.
Biosci. Biotechnol. Biochem.
62
154-156
The yiaE gene, located at 80.1 minutes on the Escherichia coli chromosome, encodes a 2-ketoaldonate reductase
1998
Yum, D-Y.; Lee, B-Y.; Hahm, D-H.; Pan, J-G.
J. Bacteriol.
180
5984-5988
-
Purification and properties of two 2,5-diketo-D-gluconate reductases from a mutant strain derived from Corynebacterium sp
1987
Sonoyama, T.; Kobayashi, K.
J. Ferment. Technol.
65
311-317
Purification and characterization of 2,5-diketo-D-gluconate reductase from Corynebacterium sp
1987
Miller, J.V.; Estell, D.A.; Lazarus, R.A.
J. Biol. Chem.
262
9016-9020
Crystal structure of 2,5-diketo-D-gluconic acid reductase A complexed with NADPH at 2.1 A resolution
1998
Khurana, S.; Powers, D.B.; Anderson, S.; Blaber, M.
Proc. Natl. Acad. Sci. USA
95
6768-6773
Identification of the yqhE and yafB genes encoding two 2,5-diketo-D-gluconate reductases in Escherichia coli
1999
Yum, D.Y.; Lee, B.Y.; Pan, J.G.
Appl. Environ. Microbiol.
65
3341-3346
Molecular modeling of substrate binding in wild-type and mutant Corynebacteria 2,5-diketo-D-gluconate reductases
2000
Khurana, S.; Sanli, G.; Powers, D.B.; Anderson, S.; Blaber, M.
Proteins
39
68-75
Alteration of the specificity of the cofactor-binding pocket of Corynebacterium 2,5-diketo-D-gluconic acid reductase A
2002
Banta, S.; Swanson, B.A.; Wu, S.; Jarnagin, A.; Anderson, S.
Protein Eng.
15
131-140
Optimizing an artificial metabolic pathway: engineering the cofactor specificity of Corynebacterium 2,5-diketo-D-gluconic acid reductase for use in vitamin C biosynthesis
2002
Banta, S.; Swanson, B.A.; Wu, S.; Jarnagin, A.; Anderson, S.
Biochemistry
41
6226-6236
Purification and identification of an Escherichia coli beta-keto ester reductase as 2,5-diketo-D-gluconate reductase YqhE
2002
Habrych, M.; Rodriguez, S.; Stewart, J.D.
Biotechnol. Prog.
18
257-261
Structural alteration of cofactor specificity in Corynebacterium 2,5-diketo-D-gluconic acid reductase
2004
Sanli, G.; Banta, S.; Anderson, S.; Blaber, M.
Protein Sci.
13
504-512
Conversion of methylglyoxal to acetol by Escherichia coli aldo-keto reductases
2005
Ko, J.; Kim, I.; Yoo, S.; Min, B.; Kim, K.; Park, C.
J. Bacteriol.
187
5782-5789
-
Characterisation of 2,5-diketo-D-gluconic acid reductase from Corynebacterium sp.
1996
Maremonti, M.; Greco Jr., G.; Wichmann, R.
Biotechnol. Lett.
18
845-850
Evaluation of the food grade expression systems NICE and pSIP for the production of 2,5-diketo-D-gluconic acid reductase from Corynebacterium glutamicum
2013
Kaswurm, V.; Nguyen, T.T.; Maischberger, T.; Kulbe, K.D.; Michlmayr, H.
AMB Express
3
7-7
Characterization of two aldo-keto reductases from Gluconobacter oxydans 621H capable of regio- and stereoselective alpha-ketocarbonyl reduction
2010
Schweiger, P.; Gross, H.; Deppenmeier, U.
Appl. Microbiol. Biotechnol.
87
1415-1426
-
Engineering of a bi-enzymatic reaction for efficient production of the ascorbic acid precursor 2-keto-L-gulonic acid
2013
Kaswurm, V.; van Hecke, W.; Kulbe, K.; Ludwig, R.
Biochem. Eng. J.
79
104-111
Show all BRENDA pathways known for 2,5-didehydro-D-gluconate
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