Ligand gamma-L-glutamylputrescine
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Basic Ligand Information
Molecular Structure

C9H19N3O3
gamma-L-glutamylputrescine
WKGTVHGVLRCTCF-ZETCQYMHSA-N
L-gamma-glutamylputrescine, N-(4-aminobutyl)-L-glutamine, N-(gamma-L-glutamyl)putrescine
Show all BRENDA pathways known for gamma-L-glutamylputrescine
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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N-(4-aminobutyl)-L-glutamine + H2O + O2 = N-(4-oxobutyl)-L-glutamine + NH3 + H2O2
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In Vivo Product in Enzyme-catalyzed Reactions (2 results)
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ATP + glutamate + putrescine = ADP + phosphate + gamma-L-glutamylputrescine
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ATP + L-glutamate + putrescine = ADP + phosphate + gamma-L-glutamylputrescine
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Substrate in Enzyme-catalyzed Reactions (2 results)
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N-(4-aminobutyl)-L-glutamine + H2O + O2 = N-(4-oxobutyl)-L-glutamine + NH3 + H2O2
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L-gamma-glutamylputrescine = putrescine + 5-oxo-L-proline
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Product in Enzyme-catalyzed Reactions (2 results)
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ATP + glutamate + putrescine = ADP + phosphate + gamma-L-glutamylputrescine
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ATP + L-glutamate + putrescine = ADP + phosphate + gamma-L-glutamylputrescine
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Enzyme Kinetic Parameters
References & Links
Literature References (3)
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A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12
2005
Kurihara, S.; Oda, S.; Kato, K.; Kim, H.G.; Koyanagi, T.; Kumagai, H.; Suzuki, H.
J. Biol. Chem.
280
4602-4608
gamma-Glutamylamine cyclotransferase - an enzyme involved in the catabolism of epsilon-(gamma-glutamyl)lysine and other gamma-glutamylamines
1981
Fink, M.; Folk, J.
Mol. Cell. Biochem.
38
59-67
gamma-Glutamylamine cyclotransferase specificity toward epsilon-(L-gamma-glutamyl)-L-lysine and related compounds
1980
Fink, M.L.; Chung, S.I.; Folk, J.E.
Proc. Natl. Acad. Sci. USA
77
4564-4568
Links to other databases for gamma-L-glutamylputrescine