Ligand gamma-glutamyl-gamma-aminobutyraldehyde
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Basic Ligand Information
Molecular Structure

C9H16N2O4
gamma-glutamyl-gamma-aminobutyraldehyde
JZNLEPLZUABCSQ-ZETCQYMHSA-N
4-(gamma-L-glutamylamino)butanal, N-(4-oxobutyl)-L-glutamine
Show all BRENDA pathways known for gamma-glutamyl-gamma-aminobutyraldehyde
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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gamma-glutamyl-gamma-aminobutyraldehyde + NAD+ + H2O = 4-(glutamylamino) butanoate + NADH + 2 H+
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)
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N-(4-aminobutyl)-L-glutamine + H2O + O2 = N-(4-oxobutyl)-L-glutamine + NH3 + H2O2
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Substrate in Enzyme-catalyzed Reactions (2 results)
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4-(gamma-L-glutamylamino)butanal + NAD+ + H2O = 4-(gamma-L-glutamylamino)butanoate + NADH + H+
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gamma-glutamyl-gamma-aminobutyraldehyde + NAD+ + H2O = 4-(glutamylamino) butanoate + NADH + 2 H+
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Product in Enzyme-catalyzed Reactions (1 result)
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N-(4-aminobutyl)-L-glutamine + H2O + O2 = N-(4-oxobutyl)-L-glutamine + NH3 + H2O2
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Enzyme Kinetic Parameters
References & Links
Literature References (2)
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A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12
2005
Kurihara, S.; Oda, S.; Kato, K.; Kim, H.G.; Koyanagi, T.; Kumagai, H.; Suzuki, H.
J. Biol. Chem.
280
4602-4608
Pathway and enzyme redundancy in putrescine catabolism in Escherichia coli
2012
Schneider, B.L.; Reitzer, L.
J. Bacteriol.
194
4080-4088
Links to other databases for gamma-glutamyl-gamma-aminobutyraldehyde