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Ligand 1,6-dihydro-beta-NAD(P)

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Natural Substrate (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.6.3.5

1,6-dihydro-beta-NADPH + H+ + O2 = beta-NADP+ + H2O2

741775, 741902, 741920, 741913, 741788, 741869, 742004, 741785

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Substrate in Enzyme-catalyzed Reactions (2 results)

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Show Substrate (2 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.6.3.5

1,6-dihydro-beta-NADPH + H+ + O2 = beta-NADP+ + H2O2

741775, 741902, 741920, 741913, 741788, 741869, 742004, 741785

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1.6.3.5

6-dihydronicotinamide adenine dinucleotide phosphate + O2 = ?

741785

-

1.6.3.5

2 entries

Enzyme Kinetic Parameters

References & Links

Literature References (8)

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Show Reference (8 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

741775

26049000

Renalase does not catalyze the oxidation of catecholamines

2015

Beaupre, B.A.; Hoag, M.R.; Moran, G.R.

Arch. Biochem. Biophys.

579

62-66

741785

27769837

Ligand binding phenomena that pertain to the metabolic function of renalase

2016

Beaupre, B.A.; Roman, J.V.; Hoag, M.R.; Meneely, K.M.; Silvaggi, N.R.; Lamb, A.L.; Moran, G.R.

Arch. Biochem. Biophys.

612

46-56

741788

28558965

The enzyme Renalase

2017

Moran, G.R.; Hoag, M.R.

Arch. Biochem. Biophys.

632

66-76

741869

26716738

The history of renalase from amine oxidase to alpha-NAD(P)H-oxidase/anomerase

2016

Severina, I.; Fedchenko, V.; Veselovsky, A.; Medvedev, A.

Biochemistry (Moscow)

10

97-109

741902

25295465

Transcriptional regulation of the novel monoamine oxidase renalase Crucial roles of transcription factors Sp1, STAT3, and ZBP89

2014

Sonawane, P.J.; Gupta, V.; Sasi, B.K.; Kalyani, A.; Natarajan, B.; Khan, A.A.; Sahu, B.S.; Mahapatra, N.R.

Biochemistry

53

6878-6892

741913

26016690

Bacterial renalase structure and kinetics of an enzyme with 2- and 6-dihydro-beta-NAD(P) oxidase activity from Pseudomonas phaseolicola

2015

Hoag, M.R.; Roman, J.; Beaupre, B.A.; Silvaggi, N.R.; Moran, G.R.

Biochemistry

54

3791-3802

741920

25531177

Metabolic function for human renalase oxidation of isomeric forms of beta-NAD(P)H that are inhibitory to primary metabolism

2015

Beaupre, B.A.; Hoag, M.R.; Roman, J.; Foersterling, F.H.; Moran, G.R.

Biochemistry

54

795-806

742004

25900362

The catalytic function of renalase A decade of phantoms

2016

Moran, G.R.

Biochim. Biophys. Acta

1864

177-186

Links to other databases for 1,6-dihydro-beta-NAD(P)

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ChEBI

PubChem