Ligand 1D-chiro-inositol

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Basic Ligand Information

Molecular Structure
Picture of 1D-chiro-inositol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H12O6
1D-chiro-inositol
CDAISMWEOUEBRE-LKPKBOIGSA-N
Synonyms:
(+)-inositol, D-chiro-Inositol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1D-chiro-inositol + NAD+ = 2D-2,3,5/4,6-pentahydroxycyclohexanone + NADH + H+
show the reaction diagram

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-oxo-D-chiro-inositol + NADH + H+ = D-chiro-inositol + NAD+
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-chiro-inositol + NAD+ = ? + NADH
show the reaction diagram
1D-chiro-inositol + NAD+ = 2D-2,3,5/4,6-pentahydroxycyclohexanone + NADH + H+
show the reaction diagram
D-chiro-inositol + S-adenosyl-L-methionine = quebrachitol + S-adenosyl-L-homocysteine
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-oxo-D-chiro-inositol + NADH + H+ = D-chiro-inositol + NAD+
show the reaction diagram
-

3D Structure of Enzyme-Ligand-Complex (PDB) (3 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1
-
pH 8.8, 60°C

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
2.9
-
pH 8.8, 60°C

References & Links

Links to other databases for 1D-chiro-inositol

ChEBI
PubChem
ChEBI
PubChem