Ligand 3-oxoadipic acid

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Basic Ligand Information

Molecular Structure
Picture of 3-oxoadipic acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H8O5
3-oxoadipic acid
RTGHRDFWYQHVFW-UHFFFAOYSA-N
Synonyms:
3-ketoadipate, 3-oxoadipate, 3-oxohexanedioic acid

Show all pahtways known for Show all pathways known for 3-oxoadipic acid

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3-oxoadipate enol-lactone + H2O = 3-oxoadipate
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Product in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
DL-2-aminoadipate + 2-oxoglutarate = 3-oxohexanedioic acid + L-glutamate
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
50% inhibition at 2.5 mM
-
0.1 mM, 56% inhibition
-
competitive inhibition
-
inhibition at pH 7.0 is higher than at pH 8.5, 3.33 mM in presence of equimolar concentrations of oxaloacetate
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Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.4
-
pH 8, 25°C

Ki Value (3 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.8
-
-

References & Links

Links to other databases for 3-oxoadipic acid

ChEBI
PubChem
ChEBI
PubChem