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BRENDA support

Ligand adenosine 5'-monophosphate

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Basic Ligand Information

Molecular Structure
Picture of adenosine 5'-monophosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H14N5O7P
adenosine 5'-monophosphate
UDMBCSSLTHHNCD-KQYNXXCUSA-N
Synonyms:
3-beta-ribofuranosyladenine 5'-monophosphate, 5'-adenosine monophosphate, 5'-adenylic acid, 5'-AMP, 5'AMP, 5-AMP, 6-aminopurine nucleotides, adenine 9-beta-D-riboside 5'-phosphate, adenine nucleotide, adenine nucleotides, adenosine-5'-monophopsphate, adenosine-5'-monophosphate, adenosine-5'-phosphate, adenosine-5-phosphate, adenosine 5'-phosphate, adenosine 5-phosphate, adenosine monophosphate, adenosine nucleotides, adenosine phosphates, adenylate, adenylic acid, adenylic acids, AMP, AMP2-
Pathway Source
Pathways
BRENDA
(5R)-carbapenem carboxylate biosynthesis, 3-phenylpropionate degradation, 6-hydroxymethyl-dihydropterin diphosphate biosynthesis, acetate fermentation, adipate degradation more
KEGG
Aldosterone synthesis and secretion, AMPK signaling pathway, Antifolate resistance, Biosynthesis of alkaloids derived from histidine and purine, Biosynthesis of cofactors more
MetaCyc
(-)-microperfuranone biosynthesis, (2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis, (3R)-N-[(2S)-1-hydroxy-6-[(3R)-3-isocyanobutanamido]hexan-2-yl]-3-isocyanobutanamide biosynthesis, (5R)-carbapenem carboxylate biosynthesis, (aminomethyl)phosphonate degradation more


Show all pahtways known for Show all BRENDA pathways known for adenosine 5'-monophosphate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (72 results)

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EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
AMP + sulfite + glutathione disulfide = adenylyl sulfate + 2 glutathione
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AMP + phosphate = adenine + alpha-D-ribose 1,5-bisphosphate
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dimethylallyl diphosphate + AMP = diphosphate + N6-(dimethylallyl)adenosine phosphate
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AMP + thymidine = adenosine + dTMP
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AMP + trans-farnesyl triphosphate = ?
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AMP + phosphoenolpyruvate + diphosphate = ATP + pyruvate + phosphate
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AMP + phosphoenolpyruvate + phosphate = ATP + pyruvate + H2O
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AMP + H2O = IMP + NH3
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AMP + diphosphate + [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine = ATP + [NEDD8 protein] + [E1 NEDD8-activating enzyme]-L-cysteine
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In Vivo Product in Enzyme-catalyzed Reactions (877 results)

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EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Arachnocampa luciferin + O2 + ATP = Arachnocampa oxyluciferin + CO2 + AMP + diphosphate + hv
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luciferin + O2 + ATP = oxyluciferin + AMP + diphosphate + CO2 + light
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luciferin + O2 + ATP = oxyluciferin + AMP + diphosphate + CO2 + light
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L-tyrosine + NADPH + H+ + ATP = L-tyrosinal + NADP+ + AMP + diphosphate
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L-2-aminoadipate + NADPH + H+ + ATP = (S)-2-amino-6-oxohexanoate + NADP+ + AMP + diphosphate
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ADP + thymidine = AMP + dTMP
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ATP + adenosine = ADP + AMP
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ADP + L-serine = AMP + O-phospho-L-serine
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ATP + phenol + H2O = AMP + phenyl phosphate + phosphate
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ATP + (R)-4-phosphopantoate + beta-alanine = AMP + diphosphate + (R)-4'-phosphopantothenate
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ATP + L-glutamine + H2O = AMP + phosphate + N5-phospho-L-glutamine
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ADP + [phosphate]n = AMP + [phosphate]n+1
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Urm1p-terminal-Gly-AMP + Uba4-SSH = Urm1p-terminal-Gly-COSH + human MOCS2A-SH + AMP
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ATP + pyruvate + phosphate = AMP + phosphoenolpyruvate + diphosphate
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ATP + pyruvate + H2O = AMP + phosphoenolpyruvate + phosphate
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ATP + rifampicin + H2O = AMP + 21-phosphorifampicin + phosphate
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[molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP + [cysteine desulfurase]-S-sulfanyl-L-cysteine = AMP + [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH2-C(O)SH + cysteine desulfurase
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a [protein]-S-sulfanyl-L-cysteine + 5-taurinomethyluridine34 in tRNA + ATP + reduced acceptor = a [protein]-L-cysteine + 5-taurinomethyl-2-thiouridine34 in tRNA + AMP + diphosphate + acceptor
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Urm1p-terminal-Gly-AMP + Uba4-SSH = Urm1p-terminal-Gly-COSH + Uba4-SH + AMP
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sulfurtransferase IscS-SSH + adenylated-tRNA-uridine(position8) = sulfurtransferase IscS-SH + tRNA-4-thiouridine(position8) + AMP
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adenosine 5'-phosphosulfate + dithiothreitol = AMP + ?
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5'-O-phosphonoadenylyl-(3'->5')-adenosine + H2O = 2 AMP
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ADP + H2O = AMP + phosphate
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5'-acylphosphoadenosine + H2O = AMP + carboxylate
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ADP-sugar + H2O = AMP + sugar phosphate
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ATP + H2O = AMP + diphosphate
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adenosine 5'-phosphosulfate + H2O = AMP + SO42-
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ATP + H2O = AMP + diphosphate
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FAD = AMP + riboflavin cyclic-4',5'-phosphate
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ATP + UDP-MurNAc-L-Ala-L-Glu = AMP + diphosphate + UDP-MurNAc-L-Ala-D-Glu
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ADP + H2O + a folded polypeptide = AMP + phosphate + an unfolded polypeptide
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ATP + L-cysteine + tRNACys = AMP + diphosphate + L-cysteinyl-tRNACys
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ATP + L-asparagine + tRNAAsn = AMP + diphosphate + L-asparaginyl-tRNAAsn
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ATP + L-isoleucine + tRNAIle = AMP + diphosphate + L-isoleucyl-tRNAIle
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ATP + L-alanine + tRNAAla = AMP + diphosphate + L-alanyl-tRNAAla
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ATP + L-valine + tRNAVal = AMP + diphosphate + L-valyl-tRNAVal
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ATP + L-glutamate + tRNAAsp = AMP + diphosphate + L-glutamyl-tRNAAsp
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tobramycin + carbamoyl phosphate + ATP + H2O = nebramycin 5' + AMP + diphosphate + phosphate
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ATP + arachidonate + CoA = AMP + diphosphate + arachidonoyl-CoA
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ATP + acetoacetate + CoA = AMP + diphosphate + acetoacetyl-CoA
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ATP + 4-hydroxybenzoate + CoA = AMP + diphosphate + 4-hydroxybenzoyl-CoA
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4-Chlorobenzoate + CoA + ATP = 4-Chlorobenzoyl-CoA + AMP + diphosphate
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3-hydroxypropanoate + ATP + coenzyme A = 3-hydroxypropanoyl-CoA + AMP + diphosphate
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ATP + 3-hydroxybenzoate + CoA = AMP + diphosphate + 3-hydroxybenzoyl-CoA
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[(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetate + ATP + CoA = AMP + diphosphate + [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA
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ATP + 4-hydroxybutanoate + CoA = AMP + diphosphate + 4-hydroxybutanoyl-CoA
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ATP + 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + CoA = AMP + diphosphate + 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA
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ATP + 2-hydroxy-7-methoxy-5-methyl-1-naphthoate + CoA = AMP + diphosphate + 2-hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA
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ATP + L-carnitine + CoA = AMP + diphosphate + L-carnitinyl-CoA
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ATP + a long-chain fatty acid + holo-[mycocerosate synthase] = AMP + diphosphate + a long-chain acyl-[mycocerosate synthase]
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ATP + L-firefly luciferin + CoA = AMP + diphosphate + L-firefly luciferyl-CoA
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ATP + D-alanine + poly(ribitol phosphate) = AMP + diphosphate + O-D-alanyl-poly(ribitol phosphate)
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ATP + 3,4-dihydroxybenzoate + holo-[aryl-carrier protein] = AMP + diphosphate + 3,4-dihydroxybenzoyl-[aryl-carrier protein]
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ATP + L-arginine + holo-[L-arginyl-carrier protein] = AMP + diphosphate + L-arginyl-[L-arginyl-carrier protein]
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ATP + 3-amino-5-hydroxybenzoate + a holo-[acyl-carrier protein] = 3-amino-5-hydroxybenzoyl-[acyl-carrier protein] + AMP + diphosphate
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ATP + (indol-3-yl)acetate + CoA = AMP + diphosphate + (indol-3-yl)acetyl-CoA
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ATP + malonate + CoA = AMP + diphosphate + malonyl-CoA
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ATP + oxalate + CoA = AMP + diphosphate + oxalyl-CoA
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3-phenylpropanoate + CoA + ATP = 3-phenylpropionyl-CoA + AMP + diphosphate
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ATP + L-alanine + [acyl-carrier protein Atu2571] = AMP + diphosphate + L-alanyl-[acyl-carrier protein Atu2571]
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ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine
show the reaction diagram
1-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + L-cysteine + ATP = 1-O-[2-(L-cysteinamido)-2-deoxy-alpha-D-glucopyranosyl]-1D-myo-inositol + AMP + diphosphate
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ATP + diphthine-[translation elongation factor 2] + NH3 = AMP + diphosphate + diphthamide-[translation elongation factor 2]
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ATP + 3-dimethylallyl-4-hydroxybenzoate + 3-amino-4,7-dihydroxycoumarin = AMP + diphosphate + 8-demethylnovobiocic acid
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L-histidine + beta-alanine + ATP = carnosine + AMP + diphosphate
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ATP + L-tyrosine + L-arginine = L-tyrosyl-L-arginine + AMP + diphosphate
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2 ATP + S-adenosyl-L-methionine + anthranilate + L-phenylalanine = cyclopeptine + 2 AMP + 2 diphosphate + S-adenosyl-L-homocysteine
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ATP + fumarate + (2S)-2,3-diaminopropionate = AMP + diphosphate + (2E)-4-[(2-amino-2-carboxyethyl)amino]-4-oxobut-2-enoate
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ATP + L-isoleucine + acetoacetyl-CoA = AMP + diphosphate + tenuazonic acid + CoA
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ATP + (R)-4'-phosphopantothenate + L-cysteine = AMP + diphosphate + N-[(R)-4'-phosphopantothenoyl]-L-cysteine
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ATP + L-2,3-diaminopropanoate + citrate = AMP + diphosphate + 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate
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ATP + 2-[(2-aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate + L-2,3-diaminopropanoate = AMP + diphosphate + 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate
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ATP + 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + 2-oxoglutarate = AMP + diphosphate + staphyloferrin B
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ATP + N5-[(S)-citryl]-D-ornithine + citrate = AMP + diphosphate + staphyloferrin A
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ATP + D-ornithine + citrate = AMP + diphosphate + N5-[(S)-citryl]-D-ornithine
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ATP + (2S,5S)-5-carboxymethylproline = AMP + diphosphate + (3S,5S)-carbapenam 3-carboxylate
show the reaction diagram
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7-carboxy-7-carbaguanine + NH3 + ATP = 7-cyano-7-carbaguanine + AMP + diphosphate + H2O
show the reaction diagram
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ATP + agmatine + [tRNAIle2]-cytidine34 = [tRNAIle2]-2-agmatinylcytidine34 + AMP + diphosphate
show the reaction diagram
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