Ligand menaquinol

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Basic Ligand Information

Molecular Structure
Picture of menaquinol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C21H26O2
menaquinol
CZHYZLLLSCZMRL-NTCAYCPXSA-N
Synonyms:
a menaquinol, reduced menaquinol, reduced menaquinone


Show all pahtways known for Show all BRENDA pathways known for menaquinol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
menaquinol + acceptor = ?
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fumarate + menaquinol = succinate + menaquinone
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NO + menaquinol = N2O + H2O + menaquinone
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menaquinol + O2 + H+[side 1] = menaquinone + H2O + H+[side 2]
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menaquinol + O2 = menaquinone + H2O
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In Vivo Product in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
menaquinone + reduced coenzyme F420 = menaquinol + oxidized coenzyme F420
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formate + menaquinone = CO2 + menaquinol
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succinate + menaquinone = fumarate + menaquinol
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protoporphyrinogen IX + 3 menaquinone = protoporphyrin IX + 3 menaquinol
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succinate + a menaquinone = fumarate + a menaquinol
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NADH + H+ + menaquinone = NAD+ + menaquinol
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dimethylsulfide + menaquinone + H2O = dimethylsulfoxide + menaquinol
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NADH + H+ + menaquinone = NAD+ + menaquinol
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Substrate in Enzyme-catalyzed Reactions (15 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
menaquinol + acceptor = ?
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propylene + menaquinol + O2 = propylene oxide + menaquinone + H2O
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fumarate + menaquinol = succinate + menaquinone
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NO + menaquinol = N2O + H2O + menaquinone
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nitrate + menaquinol = nitrite + menaquinone + H2O
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thiosulfate + menaquinol = sulfite + hydrogen sulfide + menaquinone
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thiosulfate + menaquinol = sulfite + oxidized menaquinol + sulfide
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menaquinol + O2 + H+[side 1] = menaquinone + H2O + H+[side 2]
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menaquinol + O2 = menaquinone + H2O
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menaquinol + 2 ferricytochrome c = menaquinone + 2 ferrocytochrome c + 2 H+
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Product in Enzyme-catalyzed Reactions (18 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
menaquinone + reduced coenzyme F420 = menaquinol + oxidized coenzyme F420
show the reaction diagram
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H2 + menaquinone = menaquinol
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formate + menaquinone = CO2 + menaquinol
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pyruvate + menaquinone + H2O = acetate + CO2 + menaquinol
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succinate + menaquinone = fumarate + menaquinol
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protoporphyrinogen IX + 3 menaquinone = protoporphyrin IX + 3 menaquinol
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trans-4-hydroxy-L-proline + menaquinone = (3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate + menaquinol
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NADH + H+ + menaquinone = NAD+ + menaquinol
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dimethylsulfide + menaquinone + H2O = dimethylsulfoxide + menaquinol
show the reaction diagram
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sulfite + hydrogen sulfide + menaquinone = thiosulfate + menaquinol
show the reaction diagram
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demethylmenaquinol + S-adenosyl-L-methionine = menaquinol + S-adenosyl-L-homocysteine
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NADH + menaquinone = NAD+ + reduced menaquinone
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Enzyme Cofactor/Cosubstrate (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
menaquinol is the sole electron donor to thiosulfate reductase
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Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (16 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (8 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for menaquinol

ChEBI
PubChem
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PubChem