Ligand L-3-hydroxybutyrate

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Basic Ligand Information

Molecular Structure
Picture of L-3-hydroxybutyrate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C4H8O3
L-3-hydroxybutyrate
WHBMMWSBFZVSSR-VKHMYHEASA-N
Synonyms:
(S)-3-hydroxybutanoate, (S)-3-hydroxybutyric acid, L(+)-3-hydroxybutyrate, L-(+)-3-hydroxybutyrate, L-3-hydroxybutanoate, L-3-hydroxybutyric acid

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2-hydroxyglutarate
show the reaction diagram
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ATP + L-(+)-3-hydroxybutyrate + CoA = ?
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-3-hydroxybutyrate + NADP+ = 3-oxobutyrate + NADPH
show the reaction diagram
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L-3-hydroxybutyrate + NADP+ = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-beta-hydroxy-gamma-butyrolactone + H2O = (S)-3-hydroxybutyric acid
show the reaction diagram
-
-
L-3-hydroxybutyryl-CoA + H2O = CoA + L-3-hydroxybutyrate
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

3D Structure of Enzyme-Ligand-Complex (PDB) (15 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
9.38
-
pH 9.0, 30C

KM Value (11 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
95
-
pH 9.0, 30C
4
-
-

References & Links

Links to other databases for L-3-hydroxybutyrate

ChEBI
PubChem
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PubChem