Ligand ferricytochrome c

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Basic Ligand Information

Molecular Structure

C₃₆H₃₈FeN₄O₂

ferricytochrome c

OIIXOVMUEURLTD-PVPKHRJZSA-N

Synonyms:

a ferricytochrome c, a ferrocytochrome c, ferrocytochrome c

BRENDA

ascorbate metabolism, denitrification, glycine metabolism, lactate fermentation, methylglyoxal degradation

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MetaCyc

2-deoxy-D-ribose degradation II, aerobic respiration I (cytochrome c), aerobic respiration II (cytochrome c) (yeast), ammonia oxidation I (aerobic), ammonia oxidation II (anaerobic)

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Show all BRENDA pathways known for ferricytochrome c

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (48 results)

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1.1.2.2

D-mannitol + ferricytochrome c = D-fructose + ferrocytochrome c

389622, 389620, 389621

1.1.2.3

2 entries

1.1.2.6

polyvinyl alcohol + ferricytochrome c = polyvinyl alcohol containing oxo-groups + ferrocytochrome c + H+

687857

1.1.2.9

butan-1-ol + ferricytochrome c = butanal + ferrocytochrome c + H+

688853, 738514, 687366

1.1.2.B3

phenylethanol + ferricytochrome c = phenylacetaldehyde + ferrocytochrome c

glycine + ferricytochrome c = glyoxylate + ferrocytochrome c + NH3

nitrous oxide + 2 ferrocytochrome c + 2 H+ = nitrogen + H2O + 2 ferricytochrome c

764455, 765320, 765094, 765195, 763948, 764981

1.7.2.5

2 nitric oxide + 2 ferrocytochrome c + 2 H+ = nitrous oxide + 2 ferricytochrome c + H2O

764209, 764669, 742979, 764134, 764210, 741684, 742847, 763979

nitroxyl + 2 ferrocytochrome c + O2 + H+ = nitrite + 2 ferricytochrome c + H2O

thiosulfate + ferricytochrome c = tetrathionate + ferrocytochrome c

676077, 673503

1.8.99.5

sulfite + 6 ferrocytochrome c + 6 H+ = sulfide + 6 ferricytochrome c + 3 H2O

743347

1.9.98.1

ferrocytochrome c + Fe3+ = ferricytochrome c + Fe2+

In Vivo Product in Enzyme-catalyzed Reactions (64 results)

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1.1.2.2

D-mannitol + ferricytochrome c = D-fructose + ferrocytochrome c

389622, 389620, 389621

ethanol + 2 ferricytochrome c = ethanal + 2 ferrocytochrome c

1.1.2.9

butan-1-ol + ferricytochrome c = butanal + ferrocytochrome c + H+

1.1.2.B3

phenylethanol + ferricytochrome c = phenylacetaldehyde + ferrocytochrome c

1.11.1.5

ferrocytochrome c + H2O2 = ferricytochrome c + H2O

1.3.2.3

4 entries

1.4.2.1

glycine + ferricytochrome c = glyoxylate + ferrocytochrome c + NH3

391704

1.6.2.4

2 ferricytochrome c + NADPH = 2 ferrocytochrome c + NADP+ + H+

nitrogen + H2O + 2 ferricytochrome c = nitrous oxide + 2 ferrocytochrome c + 2 H+

1.7.2.5

nitrous oxide + 2 ferricytochrome c + H2O = 2 nitric oxide + 2 ferrocytochrome c + 2 H+

hydroxylamine + 2 ferricytochrome c = nitroxyl + 2 ferrocytochrome c + 2 H+

hydrogen sulfide + 2 ferricytochrome c = sulfur + 2 ferrocytochrome c + 2 H+

1.8.2.7

thiocyanate + 2 ferricytochrome c + H2O = cyanate + sulfur + 2 ferrocytochrome c + 2 H+

1.8.99.5

sulfite + 6 ferrocytochrome c + 6 H+ = sulfide + 6 ferricytochrome c + 3 H2O

1.9.98.1

ferrocytochrome c + Fe3+ = ferricytochrome c + Fe2+

Substrate in Enzyme-catalyzed Reactions (169 results)

phenylethanol + ferricytochrome c = phenylacetaldehyde + ferrocytochrome c

ferrocytochrome c + H2O2 = ?

H2 + ferricytochrome c = H+ + ferrocytochrome c

395568, 672118, 674919

1.14.12.9

4-chlorophenylacetate + ferrocytochrome c + H+ + O2 = 3,4-dihydroxyphenylacetate + chloride + ferricytochrome c

439043

1.14.13.39

ferricytochrome c + NADPH + O2 = ferrocytochrome c + NO + NADP+

ferricytochrome c + NADH = ferrocytochrome c + NAD+ + H+

437846, 675830

1.18.1.5

reduced putidaredoxin + ferricytochrome c = oxidized putidaredoxin + ferrocytochrome c

butyryl-CoA + ferricytochrome c = butenoyl-CoA + reduced acceptor

N6-(2-isopentenyl)adenine 9-beta-D-riboside + ferricytochrome c + H2O = adenine 9-beta-D-riboside + 3-methylbut-2-enal + ferrocytochrome c

726117

1.6.2.2

NADH + ferricytochrome c = NAD+ + H+ + ferrocytochrome c

ferricytochrome c + NADH + H+ = ferrocytochrome c + NAD+

721517

1.7.1.3

ferricytochrome c + NADPH + H+ = ferrocytochrome c + NADP+ + H2O

nitrous oxide + 2 ferrocytochrome c + 2 H+ = nitrogen + H2O + 2 ferricytochrome c

764455, 765320, 765094, 765195, 763948, 764981

1.7.2.5

2 nitric oxide + 2 ferrocytochrome c + 2 H+ = nitrous oxide + 2 ferricytochrome c + H2O

764209, 764669, 742979, 764134, 764210, 741684, 742847, 763979

nitroxyl + 2 ferrocytochrome c + O2 + H+ = nitrite + 2 ferricytochrome c + H2O

NADP+ + ferrocytochrome c = NADPH + H+ + ferricytochrome c

thiosulfate + ferricytochrome c = tetrathionate + ferrocytochrome c

676077, 673503

1.8.2.6

[SoxY protein]-S-disulfanyl-L-cysteine + 6 ferricytochrome c + 3 H2O = [SoxY protein]-S-sulfosulfanyl-L-cysteine + 6 ferrocytochrome c + 6 H+

744303

1.8.3.1

nitrite + ferricytochrome c = nitric oxide + ferrocytochrome c

764106

1.8.99.5

sulfite + 6 ferrocytochrome c + 6 H+ = sulfide + 6 ferricytochrome c + 3 H2O

743347

1.9.98.1

ferrocytochrome c + Fe3+ = ferricytochrome c + Fe2+

396332

1.97.1.1

ferricytochrome c + chlorate = ferrocytochrome c + H2O + chlorite

744933

7.1.1.2

NADH + ferricytochrome c = NAD+ + H+ + ferrocytochrome c

673448, 391082

7.1.1.4

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O

718705, 719024

7.1.1.5

ferricytochrome c + O2 = ferrocytochrome c + H2O

Product in Enzyme-catalyzed Reactions (202 results)

ethanol + 2 ferricytochrome c = ethanal + 2 ferrocytochrome c

1.1.2.9

15 entries

1.1.2.B3

phenylethanol + ferricytochrome c = phenylacetaldehyde + ferrocytochrome c

1.1.2.B5

6 entries

1.1.5.12

(R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c

H2 + ferricytochrome c = H+ + ferrocytochrome c

1.14.12.9

4-chlorophenylacetate + ferrocytochrome c + H+ + O2 = 3,4-dihydroxyphenylacetate + chloride + ferricytochrome c

1.14.13.39

ferricytochrome c + NADPH + O2 = ferrocytochrome c + NO + NADP+

1.18.1.1

2 ferricytochrome c + NADH = 2 ferrocytochrome c + NAD+ + H+

2 ferricytochrome c + NADH = 2 ferrocytochrome c + NAD+ + H+

1.18.1.5

2 entries

1.18.1.7

2 ferricytochrome c + NADH = 2 ferrocytochrome c + NAD+ + H+

1.19.1.1

2 ferricytochrome c + NADPH + H+ = 2 ferrocytochrome c + NADP+ + H+

2 ferricytochrome c + NADH = 2 ferrocytochrome c + NAD+ + H+

1.5.99.12

N6-(2-isopentenyl)adenine 9-beta-D-riboside + ferricytochrome c + H2O = adenine 9-beta-D-riboside + 3-methylbut-2-enal + ferrocytochrome c

2 ferricytochrome c + NAD(P)H = 2 ferrocytochrome c + NAD(P)+ + H+

394508

1.6.5.4

2 ferricytochrome c + NADH = 2 ferrocytochrome c + NAD+ + H+

1.7.1.1

2 ferricytochrome c + NADH = 2 ferrocytochrome c + NAD+ + H+

1.7.1.15

2 entries

1.7.1.3

ferricytochrome c + NADPH + H+ = ferrocytochrome c + NADP+ + H2O

nitrogen + H2O + 2 ferricytochrome c = nitrous oxide + 2 ferrocytochrome c + 2 H+

1.7.2.5

nitrous oxide + 2 ferricytochrome c + H2O = 2 nitric oxide + 2 ferrocytochrome c + 2 H+

hydroxylamine + 2 ferricytochrome c = nitroxyl + 2 ferrocytochrome c + 2 H+

1.7.99.1

2 entries

1.8.1.2

NADP+ + ferrocytochrome c = NADPH + H+ + ferricytochrome c

1.8.1.4

2 ferricytochrome c + NADH = 2 ferrocytochrome c + NAD+ + H+

1.8.1.9

2 ferricytochrome c + NADH = 2 ferrocytochrome c + NAD+ + H+

hydrogen sulfide + 2 ferricytochrome c = sulfur + 2 ferrocytochrome c + 2 H+

1.8.2.6

[SoxY protein]-S-disulfanyl-L-cysteine + 6 ferricytochrome c + 3 H2O = [SoxY protein]-S-sulfosulfanyl-L-cysteine + 6 ferrocytochrome c + 6 H+

1.8.2.7

thiocyanate + 2 ferricytochrome c + H2O = cyanate + sulfur + 2 ferrocytochrome c + 2 H+

1.8.3.1

2 entries

1.8.99.5

sulfite + 6 ferrocytochrome c + 6 H+ = sulfide + 6 ferricytochrome c + 3 H2O

1.9.98.1

ferrocytochrome c + Fe3+ = ferricytochrome c + Fe2+

396332

1.97.1.1

ferricytochrome c + chlorate = ferrocytochrome c + H2O + chlorite

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O

7.1.1.5

ferricytochrome c + O2 = ferrocytochrome c + H2O

Enzyme Cofactor/Cosubstrate (5 results)

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1.1.2.3

722153, 722066, 743420, 743847

1.1.2.4

740447

1.3.2.3

655771, 657100, 686713, 688078, 657087, 656407

Activator in Enzyme-catalyzed Reactions (1 result)

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1.7.5.2

NOR activity is stimulated by ferrocytochrome c when phenazine methosulfate and ascorbate are both present

714147

Inhibitor in Enzyme-catalyzed Reactions (4 results)

inactivation in a biphasic reaction, immune to inactivation during turnover with nitrate

392843

7.1.1.4

0.002 mM, 50% inhibition of N,N,N',N'-tetramethyl-1,4-phenylenediamine-ascorbate dependent oxygen consumption

718705

7.1.1.9

396007

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (174 results)

25Â°C, pH 7.0, wild-type cytochrome c3

672118

1.18.1.3

4.5

pH 8.5, 30Â°C

675830

1.19.1.1

0.25

presence of flavodoxin, pH 8.0, temperature not specified in the publication

1.5

pH 7.0, 25Â°C, functional FAD-containing domain plus heme-containig domain

654345

1.7.2.1

1.33

succinylated monomeric enzyme

395063

1.8.2.1

10880

recombinant enzyme

658705

7.1.1.4

1.5

pH 7.5, 40Â°C

718705

7.1.1.9

89 entries

K_M Value (229 results)

0.0023

0.0046

0.009

presence of flavodoxin, pH 8.0, temperature not specified in the publication

0.083

0.016

0.008

pH 9.5, 30Â°C

0.0275

0.057

pH 4.5, 50Â°C

719024

7.1.1.9

90 entries

K_i Value (3 results)

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7.1.1.9

3 entries

References & Links

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Show Reference (555 entries)

Ligand ferricytochrome c

Basic Ligand Information

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (48 results)

In Vivo Product in Enzyme-catalyzed Reactions (64 results)

Substrate in Enzyme-catalyzed Reactions (169 results)

Product in Enzyme-catalyzed Reactions (202 results)

Enzyme Cofactor/Cosubstrate (5 results)

Activator in Enzyme-catalyzed Reactions (1 result)

Inhibitor in Enzyme-catalyzed Reactions (4 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (174 results)

KM Value (229 results)

Ki Value (3 results)

References & Links

Literature References (555)

k_cat Value (Turnover Number) (174 results)

K_M Value (229 results)

K_i Value (3 results)