Ligand albendazole

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Basic Ligand Information

Molecular Structure
Picture of albendazole (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C12H15N3O2S
albendazole
HXHWSAZORRCQMX-UHFFFAOYSA-N
Synonyms:
albendazol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
albendazole + [reduced NADPH-hemoprotein reductase] + O2 = albendazole S-oxide + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
albendazole + [reduced NADPH-hemoprotein reductase] + O2 = 4'-hydroxyalbendazole + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
albendazole + NADPH + H+ + O2 = albendazole S-oxide + NADP+ + H2O
show the reaction diagram
-
albendazole + [reduced NADPH-hemoprotein reductase] + O2 = albendazole S-oxide + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
albendazole + [reduced NADPH-hemoprotein reductase] + O2 = 4'-hydroxyalbendazole + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

IC50 Value (5 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.14
-
pH 7.4, temperature not specified in the publication

References & Links

Links to other databases for albendazole

ChEBI
PubChem
ChEBI
PubChem