Ligand high ionic strength

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Basic Ligand Information

Molecular Formula
BRENDA Name
InChIKey
high ionic strength

Roles as Enzyme Ligand

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
maximal activity at a high concentration of buffer-salts either alone or plus dithiothreitol and thioredoxin 1 from Escherichia coli
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Inhibitor in Enzyme-catalyzed Reactions (14 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
200 mM phosphate buffer, 70% inhibition
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slightly greater inhibition of rat than of guinea-pig enzyme at sodium succinate buffer concentrations greater 0.4 M, also markedly inhibition by 6 M NaCl and 2 M ammonium sulfate
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irreversible inactivation
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above 0.1 no cleavage of GM2
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above 200 mM KCl
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Metals and Ions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
activation, e.g. NaCl, NH4Cl, KCl, sodium acetate, essential for maximal phosphate incorporation with protamine as substrate, histone phosphorylation is suppressed
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Enzyme Kinetic Parameters

References & Links

Links to other databases for high ionic strength

ChEBI
PubChem
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