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BRENDA support

Ligand (R,R)-butane-2,3-diol

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Basic Ligand Information

Molecular Structure
Picture of (R,R)-butane-2,3-diol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C4H10O2
(R,R)-butane-2,3-diol
OWBTYPJTUOEWEK-QWWZWVQMSA-N
Synonyms:
(2R,3R)-2,3-butanediol, (2R,3R)-butane-2,3-diol, (R,R)-2,3-butanediol, (R,R)-butanediol, 2R,3R-butanediol, D-(-)-2,3-butanediol, D-(-)2,3-butanediol, D-2,3-butanediol


Show all pahtways known for Show all BRENDA pathways known for (R,R)-butane-2,3-diol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (17 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(2R,3R)-2,3-butanediol + NADP+ = (R)-2-acetoin + NADPH + H+
show the reaction diagram
-
(R,R)-butane-2,3-diol + NAD+ = ?
show the reaction diagram
-
(2R,3R)-2,3-butanediol + pyrroloquinoline quinone = ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (13 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
isoforms AC6 and AC7show about 30% stimulation of activity with 100 mM D-(-)-2,3-butanediol, isoform AC9 shows about 10% stimulation of activity with 100 mM D-(-)-2,3-butanediol
-

3D Structure of Enzyme-Ligand-Complex (PDB) (310 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (10 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
740
-
cosubstrate: NADP+, pH 7.5, 80°C
591
-
at pH 10.0 and 30°C

KM Value (19 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
15.2
-
cosubstrate: NADP+, pH 7.5, 80°C
7.25
-
at pH 10.0 and 30°C
0.76
-
pH 10.0, 50°C, recombinant enzyme

References & Links

Links to other databases for (R,R)-butane-2,3-diol

ChEBI
PubChem
ChEBI
PubChem