[protein]-N6-(octanoyl)-L-lysine + an [Fe-S] cluster scaffold protein carrying a [4Fe-4S]2+ cluster + 2 S-adenosyl-L-methionine + 2 oxidized [2Fe-2S] ferredoxin + 6 H+ = [protein]-N6-[(R)-dihydrolipoyl]-L-lysine + an [Fe-S] cluster scaffold protein + 2 sulfide + 4 Fe3+ + 2 L-methionine + 2 5'-deoxyadenosine + 2 reduced [2Fe-2S] ferredoxin

7.2.2.12

ATP + H2O + Fe3+/out = ADP + phosphate + Fe3+/in

7.2.2.7

ATP + H2O + Fe3+/out = ADP + phosphate + Fe3+/in

210304, 0, 210302, 210306, 210307, 210308, 210301, 210309, 210305, 210303

Enzyme Cofactor/Cosubstrate (2 results)

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1.8.2.1

2 entries

Activator in Enzyme-catalyzed Reactions (53 results)

pMMO, optimal at 5.0 mM

438944

1.18.1.2

0.5 microM Fe(III)-citrate and 0.5 microM Fe(III)-EDTA induces Fprs

strong activation

10 mM, 115% of initial activity

696894

3.2.1.52

stimulates galactosaminidase activitiy of form I

393673

3.4.19.13

strong activation

757351

Inhibitor in Enzyme-catalyzed Reactions (1474 results)

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1.1.1.153

1 mM inhibits entirely

1 mM, 74% residual activity

724592

1.1.1.205

11% inhibition at 1 nM

347958

1.1.1.206

0-15% inactivation at 1 mM

348024

1.1.1.216

complete inhibition at 1 mM

complete inhibition at 1 mM

711181

1.1.1.274

0.5 mM, strong inhibition

440304

1.1.1.28

1 mM, 73% residual activity

760237

1.1.1.304

1 mM, 2% of initial activity with substrate diacetyl, 3.5% with substrate 2,3-butanediol, respectively

strong inhibition at 0.5 mM

440304

1.1.1.363

1 mM, 47.3% loss of activity. 5 mM, 95.2% loss of activity

761295

1.1.1.37

complete inhibition at 5 mM

27.2% residual activity at 5 mM

strong inhibition

15% inhibition at 1 mM

1 mM, 30% residual activity

724592

1.1.1.B20

inhibits diacetyl and (3S/3R)-acetoin reduction

721397

1.1.1.B3

1 mM, 44% residual activity

739940

1.1.1.B4

0.5 mM, 68% of initial activity

10 mM, wild-type enzyme retains approximately 80% of its activity, mutant enzyme Y169C/A211C retains 50-60% activity

1 mM, 54% inhibition

complete inhibition at 10 mM

741032

1.1.99.14

73% residual activity at 1 mM

1 mM, 91% inhibition

inhibits the enzyme at 1-10 mM

90% inhibition at 0.1 mM

95% inhibition at 0.1 mM

complete inhibition at 1 mM

inhibits the light emission by dinoflagellate luciferase

less than 10% activity at 1 mM

734171

1.14.11.56

2 mM, 68% residual activity

1 mM, 56% inhibition

1 mM, moderate inhibition

684641

1.14.13.24

inhibits the enzyme activity at 0.5 mM by about 50%

764754

1.14.13.244

0.1 mM, 77% residual activity

slight effect, crude enzyme extract

3% residual activity at 1 mM

743011

1.14.14.20

0.1 mM inhibits by 23%, 1 mM completely inhibits; complete inhibition at 1 mM

2 mM, 67% loss of activity

5 mM, 65% inhibition

83.5% inhibition at 1 mM

complete inhibition at 1 mM

712957

1.2.1.48

1 mM causes complete inhibition

390325

1.2.1.70

10 mM FeCl3, 80% inhibition

655401

1.2.1.94

0.1 mM, 15% residual activity

741259

1.2.3.4

10 mM concentration 35% inhibition

288388

1.21.3.7

91% residual activity at 2 mM Fe3+

5 mM, 99% loss of activity

762858

1.3.3.5

52.1% residual activity at 5 mM

10 mM, 85% inhibition of reductive amination

349573

1.4.1.9

1 mM, no residual activity

743093

1.4.1.B2

0.5 mM, 8% inhibition at pH 8.9, no effect on activity at pH 7.8

696177

1.4.3.11

about 42% residual activity at 1 mM

10.78% residual activity at 3 mM

725810

1.4.3.5

2.85 mM, 26% inhibition of pyridoxamine 5'-phosphate oxidation, 50% inhibition of pyridoxine oxidation

slight inhibition

less potent inhibitor, effect cannot reversed by EDTA