Ligand (1'S)-averantin

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Basic Ligand Information

Molecular Structure
Picture of (1'S)-averantin (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C20H20O7
(1'S)-averantin
WGPOPPKSQRZUTP-LBPRGKRZSA-N
Synonyms:
((1'S)-averantin, (1) (1'S)-averantin, (2) (1'S)-averantin, 5'-hydroxyaverantin

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5'-hydroxyaverantin + NADP+ = (1'S)-5'-oxoaverantin + NADPH + H+
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
norsolorinic acid + NADPH + H+ = (1'S)-averantin + NADP+
show the reaction diagram
-
-
averantin + [reduced NADPH-hemoprotein reductase] + O2 = 5'-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(1'S)-averantin + NADP+ = norsolorinic acid + NADPH + H+
show the reaction diagram
-
5'-hydroxyaverantin + NADP+ = (1'S)-5'-oxoaverantin + NADPH + H+
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
norsolorinic acid + NADPH + H+ = (1'S)-averantin + NADP+
show the reaction diagram
-
-
averantin + [reduced NADPH-hemoprotein reductase] + O2 = 5'-hydroxyaverantin + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-

Enzyme Kinetic Parameters

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0426
-
pH 7.5, 37C

References & Links

Links to other databases for (1'S)-averantin

ChEBI
PubChem
ChEBI
PubChem