Ligand NAD+

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Basic Ligand Information

Molecular Structure

Picture of NAD+ (click for magnification)

C₂₁H₂₈N₇O₁₄P₂

NAD+

BAWFJGJZGIEFAR-NNYOXOHSSA-O

Synonyms:

beta-NAD(P)+, beta-NAD+, betaNAD+, coenzyme I, DPN, NAD+-analogs, NAD+-analogues, NAD analogs, nicotinamide adenine dinucleotide, P1-(nicotinamide-ribos-5'-yl)-P2(adenine-arabinofuranos-5'-yl) diphosphate

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (877 results)

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1.1.1.1

10 entries

1.1.1.103

L-threonine + NAD+ = (2S)-2-amino-3-oxobutanoate + NADH + H+

285717, 285720, 285701, 737579, 285707, 285708, 285713, 285705, 668567, 285721, 285719, 738606, 285715, 668536, 669546, 285703, 285704, 285706, 285709, 285710, 285711, 285712, 285714, 285716, 285718, 285702, 722747, 738933, 687461, 688343, 721272, 729112, 668111

1.1.1.105

4 entries

1.1.1.106

(R)-pantoate + NAD+ = (R)-4-dehydropantoate + NADH

207979, 285729, 285731

1.1.1.107

pyridoxal + NAD+ = 4-pyridoxolactone + NADH + H+

80781, 721873, 667329, 688568

indolelactate + NAD+ = indolepyruvate + NADH

285756

1.1.1.114

D-apiitol + NAD+ = D-apiose + NADH

D-glucose + NAD+ = D-glucono-1,5-lactone + NADH + H+

739713, 668049

1.1.1.12

L-arabinitol + NAD+ = L-xylulose + NADH + H+

285788, 285787, 285789, 246416, 721913, 740772, 739939, 740145, 738728, 740218, 668063

2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH

285818

1.1.1.126

2-dehydro-3-deoxy-D-gluconate + NAD+ = (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + NADH + H+

739788

1.1.1.127

2-dehydro-3-deoxy-D-gluconate + NAD+ = (4S)-4,6-dihydroxy-2,5-dioxohexanoate + NADH

285821, 285820

1.1.1.129

L-threonate + NAD+ = 3-dehydro-L-threonate + NADH

285825

1.1.1.13

L-arabinitol + NAD+ = L-ribulose + NADH + H+

D-sorbitol 6-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+

5-O-methyl-myo-inositol + NAD+ = 5D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + NADH

285940

1.1.1.144

perillyl alcohol + NAD+ = perillyl aldehyde + NADH

3alpha-hydroxy-5beta-androstane-17-one + NAD+ = 5beta-androstane-3,17-dione + NADH

286009

1.1.1.159

cholate + NAD+ = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + NADH + H+

740787, 741371, 740971

1.1.1.16

10 entries

1.1.1.163

cyclopentanol + NAD+ = cyclopentanone + NADH

286094

1.1.1.165

2-butyne-1,4-diol + NAD+ = 4-hydroxybut-2-ynal + NADH

286099

1.1.1.166

(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD+ = (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + NADH

286100

1.1.1.167

hydroxymalonate + NAD+ = oxomalonate + NADH

286101

1.1.1.169

(R)-pantoate + NAD+ = 2-dehydropantoate + NADH + H+

L-rhamnose + NAD+ = L-rhamno-1,4-lactone + NADH

347732, 347733, 687737, 347736, 686697

cholate + NAD+ = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADH + H+

740787

1.1.1.178

2-methyl-3-hydroxybutyryl-CoA + NAD+ = 2-methylacetoacetyl-CoA + NADH

286122, 286121, 286123, 286120

1.1.1.18

5 entries

1.1.1.181

cholest-5-ene-3beta,7alpha-diol + NAD+ = 7alpha-hydroxycholest-4-en-3-one + NADH

286129

1.1.1.183

geraniol + NAD+ = geranial + NADH

cinnamyl alcohol + NAD+ = cinnamaldehyde + NADH + H+

sorbitol + NAD+ = D-fructose + NADH + H+

711381, 711427

1.1.1.211

a long-chain (S)-3-hydroxyacyl-CoA + NAD+ = a long-chain 3-oxoacyl-CoA + NADH + H+

740102, 740106, 740438, 740641, 741064

vomifoliol + NAD+ = dehydrovomifoliol + NADH

trans-4-hydroxycyclohexanecarboxylate + NAD+ = 4-oxocyclohexanecarboxylate + NADH

(+)-cis-sabinol + NAD+ = (+)-sabinone + NADH

N-acetyl-D-mannosamine + NAD+ = N-acetyl-D-mannosaminolactone + NADH + H+

389506, 389505, 740014

1.1.1.237

3-(4-hydroxyphenyl)lactate + NAD+ = 4-hydroxyphenylpyruvate + NADH

286350, 286351, 286349

N-acetyl-D-glucosamine + NAD+ = N-acetyl-D-glucosaminate + NADH

286366

1.1.1.243

(4R,6S)-trans-carveol + NAD+ = (4R)-carvone + NADH

cyclohexanol + NAD+ = cyclohexanone + NADH

12556, 246371, 286378

1.1.1.25

2 entries

1.1.1.251

Galactitol-1-phosphate + NAD+ = L-Tagatose 6-phosphate + NADH

6-hydroxyhexanoate + NAD+ = 6-oxohexanoate + NADH

246371

1.1.1.259

3-hydroxypimeloyl-CoA + NAD+ = 3-oxopimeloyl-CoA + NADH

207950, 207951, 207952

1.1.1.26

2 entries

1.1.1.261

sn-glycerol-1-phosphate + NAD+ = dihydroxyacetone phosphate + NADH

207958, 207959, 207960, 207956

(+)-trans-carveol + NAD+ = (+)-carvone + NADH

xanthoxin + NAD+ = abscisic aldehyde + NADH + H+

663177, 663054, 662533, 663150, 663053, 663149, 726201

1.1.1.290

7 entries

1.1.1.3

L-homoserine + NAD+ = L-aspartate 4-semialdehyde + NADH + H+

retinol + NAD+ = retinal + NADH + H+

xylitol + NAD+ = D-xylose + NADH + H+

721343, 722851, 721848, 740782

1.1.1.308

(R)-2,3-dihydroxypropane-1-sulfonate + 2 NAD+ + H2O = (R)-sulfolactate + 2 NADH + 2 H+

(S)-1-phenylethanol + NAD+ = acetophenone + NADH + H+

L-galactose + NAD+ = L-galactono-1,4-lactone + NADH + H+

739807, 725792, 726199, 716321, 713274, 713254

1.1.1.326

10-hydroxy-alpha-humulene + NAD+ = zerumbone + NADH + H+

717593

1.1.1.331

(-)-secoisolariciresinol + 2 NAD+ = (-)-matairesinol + 2 NADH + 2 H+

742033, 741681, 743278, 743768, 743611

1.1.1.335

UDP-N-acetyl-alpha-D-mannosamine + 2 NAD+ + H2O = UDP-N-acetyl-alpha-D-mannosaminuronate + 2 NADH + 2 H+

743790

1.1.1.336

UDP-N-acetyl-alpha-D-mannosamine + 2 NAD+ + H2O = UDP-N-acetyl-alpha-D-mannosaminuronate + 2 NADH + 2 H+

742145

1.1.1.34

(R)-mevalonate + CoA + 2 NAD+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 H+

740104

1.1.1.343

6-phospho-D-gluconate + NAD+ = D-ribulose 5-phosphate + CO2 + NADH + H+

740967, 721369, 741428, 729742, 741424

1.1.1.345

(R)-2-hydroxycarboxylate + NAD+ = a 2-oxocarboxylate + NADH + H+

743180

1.1.1.347

geraniol + NAD+ = geranial + NADH + H+

(S)-ureidoglycolate + NAD+ = oxalurate + NADH + H+

723597

1.1.1.351

6-phospho-D-gluconate + NAD+ = D-ribulose 5-phosphate + CO2 + NADH + H+

286819

1.1.1.352

5'-hydroxyaverantin + NAD+ = 5'-oxoaverantin + NADH + H+

721331

1.1.1.354

(2E,6E)-farnesol + NAD+ = (2E,6E)-farnesal + NADH + H+

D-glucose 6-phosphate + NAD+ = 6-phospho-D-glucono-1,5-lactone + NADH + H+

740461, 721400, 721401, 721402, 721580, 721584, 722578, 722590, 740878, 740421, 723718, 742533

1.1.1.366

2 entries

1.1.1.368

6-hydroxycyclohex-1-ene-1-carbonyl-CoA + NAD+ = 6-oxocyclohex-1-ene-1-carbonyl-CoA + NADH + H+

741556, 724904

1.1.1.369

1D-chiro-inositol + NAD+ = 2D-2,3,5/4,6-pentahydroxycyclohexanone + NADH + H+

scyllo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH + H+

712965

1.1.1.374

UDP-N-acetyl-alpha-D-glucosamine + NAD+ = UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose + NADH + H+

726671

1.1.1.375

(S)-malate + NAD+ = oxaloacetate + NADH + H+

726931

1.1.1.376

L-arabinose + NAD+ = L-arabinono-1,4-lactone + NADH + H+

739943

1.1.1.379

(R)-mandelate + NAD+ = phenylglyoxylate + NADH + H+

(1R,2S,5R,6S)-dihydroanticapsin + NAD+ = (1R,2S,6R)-anticapsin + NADH + H+

L-serine + NAD+ = ?

2-dehydro-3-deoxy-L-galactonate + NAD+ = 2,5-didehydro-3-deoxy-L-galactonate + NADH + H+

sulfoquinovose + NAD+ = 6-deoxy-6-sulfo-D-glucono-1,5-lactone + NADH + H+

743854, 735194

1.1.1.391

3beta,7beta-dihydroxy-5beta-cholan-24-oic acid + NAD+ = 7beta-hydroxy-3-oxo-5beta-cholan-24-oic acid + NADH + H+

736216

1.1.1.394

3,4-dihydroxy-2-methyl-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NAD+ = 4-hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADH + H+

733094

1.1.1.395

3alpha-hydroxy bile acid CoA ester + NAD+ = 3-oxo bile acid CoA ester + NADH + H+

(2S,3R)-2-hydroxy-3-(indol-3-yl)butanoate + NAD+ = (R)-3-(indol-3-yl)-2-oxobutanoate + NADH + H+

739549

1.1.1.399

(R)-2-hydroxyglutarate + NAD+ = 2-oxoglutarate + NADH + H+

287546, 738484, 738269, 738426, 738853

1.1.1.4

6 entries

1.1.1.40

(S)-malate + NAD+ = pyruvate + CO2 + NADH

740773

1.1.1.400

2-methylpropane-1,2-diol + NAD+ = 2-hydroxy-2-methylpropanal + NADH + H+

737503

1.1.1.401

2-dehydro-3-deoxy-L-rhamnonate + NAD+ = 2,4-didehydro-3-deoxy-L-rhamnonate + NADH + H+

697897, 733813

1.1.1.402

D-erythritol 1-phosphate + NAD+ = D-erythrulose 1-phosphate + NADH + H+

641259

1.1.1.403

D-threitol + NAD+ = D-erythrulose + NADH + H+

736313, 738713

1.1.1.404

2,3,5,6-tetrachlorohydroquinone + NAD+ = 2,3,5,6-tetrachloro-1,4-benzoquinone + NADH + H+

D-altritol + NAD+ = D-tagatose + NADH + H+

narcotine hemiacetal + NAD+ = noscapine + NADH + H+

L-arabinose + NAD+ = L-arabinono-1,4-lactone + NADH + H+

80759, 727442

1.1.1.47

D-glucose + NAD+ = D-glucono-1,5-lactone + NADH + H+

740382, 739861, 739842, 740857, 740388, 740529

pregnenolone + NAD+ = progesterone + NADH + H+

677079

1.1.1.52

3alpha-hydroxy-5beta-cholanate + NAD+ = 3-oxo-5beta-cholanate + NADH

287082

1.1.1.54

3-methyl-2-buten-1-ol + NAD+ = 3-methyl-2-buten-1-al + NADH

D-mannonate + NAD+ = D-fructuronate + NADH

287128, 287129, 287131, 287132, 287133, 287130

1.1.1.58

D-altronate + NAD+ = D-tagaturonate + NADH

287128, 287129, 287137, 287138, 287139, 287140, 287130

1.1.1.59

3-hydroxypropanoate + NAD+ = 3-oxopropanoate + NADH + H+

287142, 695710, 5348, 738640

testosterone + NAD+ = androst-4-ene-3,17-dione + NADH + H+

287225

1.1.1.67

D-mannitol + NAD+ = D-fructose + NADH + H+

287248, 740930, 287238, 287241, 287237, 287242, 287246, 287249, 287253, 287243, 287247, 287252, 287255, 287256, 287240, 287257, 287258, 287244, 94720, 285866, 287250, 287251, 94717, 287239, 741375, 686764, 722234

1.1.1.69

D-gluconate + NAD+ = 5-dehydro-D-gluconate + NADH + H+

739569

1.1.1.7

propane-1,2-diol-1-phosphate + NAD+ = hydroxyacetone phosphate + NADH

1-octanol + NAD+ = n-octanal + NADH

287296, 287297

1.1.1.75

L-1-aminopropan-2-ol + NAD+ = aminoacetone + NADH

287302, 287298, 287307, 287300, 287303, 287305, 287306, 287299, 287304, 287301

D-glycerate + NAD+ = hydroxypyruvate + NADH + H+

737745, 739242

1.1.1.83

D-malate + NAD+ = pyruvate + CO2 + NADH

287431

1.1.1.84

(R)-3,3-dimethylmalate + NAD+ = 3-methyl-2-oxobutanoate + CO2 + NADH

207978, 207979, 207980

(R)-mevalonate + CoA + 2 NAD+ = 3-hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 H+

L-(+)-tartrate + NAD+ = oxaloglycolate + NADH

xylitol + NAD+ = L-xylulose + NADH + H+

(S)-1-phenylethanol + NAD+ = acetophenone + NADH + H+

701031, 725726, 741747, 723841

1.1.1.B4

(R)-1-phenylethanol + NAD+ = acetophenone + NADH + H+

742305, 725726, 723841

1.1.1.B40

9 entries

1.1.1.B58

L-erythritol 4-phosphate + NAD+ = L-3-tetrulose 4-phosphate + NADH + H+

737165

1.1.1.B65

(R)-mandelate + NAD+ = phenylglyoxylate + NADH + H+

743100

1.1.99.14

glycolate + NAD+ = glyoxylate + NADH

4-pyridoxate + NAD+ = 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + NADH + H+

744475

1.11.1.1

NAD+ + H2O = NADH + H2O2

658242, 660156

1.12.1.2

H2 + NAD+ = H+ + NADH

439633, 656298, 742695, 742373, 742858, 743797, 656734, 654821, 742575, 439692, 439694, 654388, 654562, 655638, 654285, 655890, 655307, 672067

1.12.1.4

H2 + NAD+ + oxidized ferredoxin = H+ + NADH + reduced ferredoxin

741931

1.16.1.1

Hg + NAD+ + H+ = Hg2+ + NADH

726730

1.16.1.7

2 Fe(II)-siderophore + NAD+ + H+ = 2 Fe(III)-siderophore + NADH

728066, 728202, 728795

1.17.1.1

CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD+ + H2O = CDP-4-dehydro-6-deoxy-D-glucose + NADH + H+

745601

1.17.1.11

formate + 2 NAD+ + 2 oxidized ferredoxin iron-sulfur cluster = CO2 + 2 NADH + 2 reduced ferredoxin iron-sulfur cluster

nicotinate + H2O + NAD+ = 6-hydroxynicotinate + NADH + H+

745661

1.17.1.9

formate + NAD+ = CO2 + NADH

740767, 740572, 726427, 740027, 743561, 740109, 740431, 725739, 740947, 742266, 743143, 743726, 726088, 724766, 740747, 740974, 740581, 740775, 740370, 741359, 288122, 725735, 743846, 741207, 724079, 739917, 739921, 740079, 740308, 740397, 742376, 724094, 725746, 739795, 740223, 740874, 741547, 742752, 288087, 288084, 288098, 288092, 288117, 288101, 287875, 288106, 655873, 657414, 725222, 741289

1.17.3.2

hypoxanthine + NAD+ + H2O = xanthine + NADH

744517, 745064, 744493, 745461, 745585, 745473, 745709

1.18.1.1

reduced rubredoxin + NAD+ = oxidized rubredoxin + NADH

reduced putidaredoxin + NAD+ = oxidized putidaredoxin + NADH + H+

744581, 744637

1.18.1.7

reduced [2Fe-2S] ferredoxin + NAD+ + H+ = oxidized [2Fe-2S] ferredoxin + NADH

5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + NAD+ + H2O = 3-hydroxy-2-methylpyridine-4,5-dicarboxylate + NADH + H+

DL-glyceraldehyde 3-phosphate + phosphate + NAD+ = 3-phospho-D-glyceroyl phosphate + NADH + H+

725013

1.2.1.15

3-oxopropanoate + NAD+ + H2O = malonate + NADH

3-oxopropanoate + CoA + NAD+ = acetyl-CoA + CO2 + NADH

741539, 288057, 288056

benzaldehyde + NAD+ + H2O = benzoate + NADH + H+

390242, 4801, 4814, 288329, 288330, 288331, 389583, 390225, 288333, 724140, 288328, 389586, 389587, 390233, 390237, 390239, 390240, 390241, 390228, 390234, 390243, 700759, 699798

L-2-aminoadipate-semialdehyde + NAD+ = L-2-aminoadipate + NADH

(R)-4-dehydropantoate + NAD+ = (R)-3,3-dimethylmalate + NADH

L-glutamate 5-semialdehyde + phosphate + NAD+ = L-glutamyl 5-phosphate + NADH + H+

697283

1.2.1.42

hexadecanal + CoA + NAD+ = hexadecanoyl-CoA + NADH + H+

4-hydroxyphenylacetaldehyde + NAD+ = 4-hydroxyphenylacetate + NADH + H+

288289

1.2.1.54

4-guanidinobutanal + NAD+ = 4-guanidinobutanoate + NADH

2168, 288069, 288074

1.2.1.58

phenylglyoxylate + NAD+ + CoA-SH = benzoyl-S-CoA + CO2 + NADH

11535, 718

1.2.1.59

D-glyceraldehyde 3-phosphate + phosphate + NAD+ = 3-phospho-D-glyceroyl phosphate + NADH + H+

723857, 743222, 741524, 743026, 725013

1.2.1.60

5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH

288297, 288299, 288300, 288301, 288298, 288303, 288040

1.2.1.61

2 entries

1.2.1.62

4-formylbenzenesulfonate + NAD+ + H2O = 4-sulfobenzoate + NADH

207945, 207946, 207947

coniferyl aldehyde + H2O + NAD+ = ferulate + NADH

288325, 654264

1.2.1.69

fluroracetaldehyde + NAD+ + H2O = fluoroacetate + NADH

D-erythrose 4-phosphate + NAD+ = 4-phosphoerythronate + NADH

661984

1.2.1.73

2-sulfoacetaldehyde + H2O + NAD+ = sulfoacetate + NADH + H+

675824, 684762, 684747

1.2.1.74

abietadienal + H2O + NAD+ = abietate + NADH + H+

690605, 694704

1.2.1.78

2-carboxybenzaldehyde + NAD+ + H2O = o-phthalic acid + NADH + H+

639268, 699291

1.2.1.79

succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+

beta-apo-4'-carotenal + NAD+ + H2O = beta-apo-4'-carotenoic acid + NADH + H+

714988

1.2.1.85

2-hydroxymuconate-6-semialdehyde + NAD+ + H2O = (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + NADH + 2 H+

741776

1.2.1.87

propanal + CoA + NAD+ = propanoyl-CoA + NADH + H+

D-glyceraldehyde 3-phosphate + NAD+ + H2O = 3-phospho-D-glycerate + NADH + H+

725013

1.2.1.90

D-glyceraldehyde 3-phosphate + NAD+ + H2O = 3-phospho-D-glycerate + NADH + 2 H+

288349, 727825, 727454

1.2.1.94

3 entries

1.2.1.96

4-hydroxybenzaldehyde + NAD+ + H2O = 4-hydroxybenzoate + NADH + H+

733948

1.2.1.97

(2S)-3-sulfolactaldehyde + NAD+ + H2O = (2S)-3-sulfolactate + NADH + H+

735194

1.2.1.98

2-hydroxy-2-methylpropanal + NAD+ + H2O = 2-hydroxy-2-methylpropanoate + NADH + H+

pyruvate + CoA + NAD+ = acetyl-CoA + CO2 + NADH

710839, 654734, 698954, 699383, 710828, 713120, 656612, 656580, 657068, 696036, 711542, 713056, 654741, 654462, 655474, 654647

lactate + 2 NAD+ + 2 reduced ferredoxin iron-sulfur cluster = pyruvate + 2 NADH + 2 oxidized ferredoxin iron-sulfur cluster

7beta-hydroxy-3-oxochol-24-oyl-CoA + NAD+ = 7beta-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+

prephenate + NAD+ = 4-hydroxyphenylpyruvate + CO2 + NADH

740420, 740113

1.3.1.14

dihydroorotate + NAD+ = orotate + NADH + H+

390562, 390568, 390569, 390565, 390561

(-)-3,5-cyclohexadiene-1,2-diol-1-carboxylic acid + NAD+ = catechol + CO2 + NADH

644712, 644717, 644716, 644718, 644719, 644715, 644720, 644713, 390588

1.3.1.28

(2S,3S)-2,3-dihydro-2,3-dihydroxybenzoate + NAD+ = 2,3-dihydroxybenzoate + NADH + H+

chalcone + NAD+ = dihydrochalcone + NADH + H+

acyl-CoA + NAD+ = trans-2,3-didehydroacyl-CoA + NADH

390808, 390807, 390806

1.3.1.49

(+)-cis-3,4-dihydrophenanthrene-3,4-diol + NAD+ = phenanthrene-3,4-diol + NADH

cis-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD+ = 2,3-dihydroxy-p-cumate + NADH

246450

1.3.1.6

succinate + NAD+ = fumarate + NADH + H+

710873, 713389, 696425, 712285

1.3.1.62

pimeloyl-CoA + NAD+ = 6-carboxyhex-2-enoyl-CoA + NADH

288483

1.3.1.64

cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+ = 4,5-dihydroxyphthalate + NADH + H+

meso-tartrate + NAD+ = dihydroxyfumaric acid + NADH

349356

1.3.1.76

precorrin-2 + NAD+ = sirohydrochlorin + NADH + H+

644278, 644283, 649647, 651626, 651633, 485092, 649745, 653297

1.3.1.78

L-arogenate + NAD+ = L-tyrosine + NADH + CO2

390781, 390801, 390793, 390560, 390531, 390557, 390796, 390805, 390794, 390788

1.3.1.79

L-arogenate + NAD+ = L-tyrosine + NADH + CO2

L-erythro-3,5-diaminohexanoate + H2O + NAD+ = 5-amino-3-oxohexanoate + NH3 + NADH + H+

391432, 391434

1.4.1.12

(2R,4S)-2,4-diaminopentanoate + H2O + NAD+ = (2R)-2-amino-4-oxopentanoate + NH3 + NADH + H+

742928

1.4.1.14

2 L-glutamate + NAD+ = L-glutamine + 2-oxoglutarate + NADH + H+

725140, 724035, 726482

L-tryptophan + NAD+ + H2O = (indol-3-yl)pyruvate + NH3 + NADH + H+

741706, 742947, 742410

1.4.1.2

L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+

724249, 725887, 726164, 726245, 726119, 727059, 726044, 725797, 724888, 724970, 391559, 724596, 724935, 711526, 711875, 710758, 725834, 724938, 391544, 391558, 661800, 711601

L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+

725445, 725866, 725956, 724789, 724653, 712431, 712827

1.4.1.5

L-Amino acid + H2O + NAD+ = ?

L-erythro-3,5-diaminohexanoate + H2O + NAD+ = 5-amino-3-oxohexanoate + NH3 + NADH + H+

696177

1.4.1.B5

2 L-glutamate + NAD+ = L-glutamine + 2-oxoglutarate + NADH + H+

(-)-ephedrine + NAD+ = (R)-2-methylimino-1-phenylpropan-1-ol + NADH

tauropine + NAD+ + H2O = taurine + pyruvate + NADH

655275

1.5.1.26

beta-alanopine + NAD+ + H2O = beta-alanine + pyruvate + NADH + H+

725659

1.5.1.37

FADH2 + NAD+ = FAD + NADH + H+

742137

1.5.1.39

FMNH2 + NAD+ = FMN + NADH + H+

716204

1.5.1.42

FMNH2 + NAD+ = FMN + NADH + H+

N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O = L-lysine + 2-oxoglutarate + NADH + H+

NADPH + NAD+ = NADP+ + NADH

743251, 742371, 742182, 725040

1.6.1.2

3 entries

1.6.1.3

NADPH + NAD+ = NADP+ + NADH

741856, 392667, 742386, 392576, 723924, 724795, 724928, 722576

1.8.1.3

hypotaurine + H2O + NAD+ = taurine + NADH

NAD+ + 5,6-dimethylbenzimidazole = nicotinamide + alpha-5,6-dimethylbenzimidazole adenine dinucleotide

NAD+ + glycine + [ADP-thiazole synthase]-L-cysteine = nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + [ADP-thiazole synthase]-dehydroalanine + 3 H2O

745881

2.4.2.B12

NAD+ + [actin]-L-arginine177 = nicotinamide + [actin]-N-(ADP-D-ribosyl)-L-arginine177 + H+

738011, 738873, 739437, 739000

NAD+ + [archaeal chromatin protein Alba]-N6-acyl-L-lysine = nicotinamide + [archaeal chromatin protein Alba]-L-lysine + 2'-O-acyl-ADP-ribose

ATP + NAD+ = ADP + NADP+

677335, 641200, 641198, 641193, 641197, 641188, 641186, 641203, 674616

2.7.1.86

ATP + NAD+ = ADP + NADP+

NAD+ + H2O = NMN + AMP

246826, 246814, 246827, 246817, 246801, 246828, 246804, 246825, 246831, 246829, 246809, 719535, 246824, 246813

In Vivo Product in Enzyme-catalyzed Reactions (436 results)

L-xylulose + NADH = L-xylitol + NAD+

1.1.1.104

4-oxo-proline + NADH = 4-hydroxy-L-proline + NAD+

D-ribulose + NADH + H+ = D-arabinitol + NAD+

1.1.1.127

2,5-didehydro-3-deoxy-D-gluconate + NADH + H+ = 2-dehydro-3-deoxy-D-gluconate + NAD+

1.1.1.140

D-fructose 6-phosphate + NADH = D-sorbitol 6-phosphate + NAD+

1.1.1.141

(5Z,13E)-11alpha-hydroxy-9,15-dioxoprost-5,13-dienoate + NADH = (5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate + NAD+

1.1.1.145

2 entries

1.1.1.159

7-keto-lithocholic acid + NADH = cheno-deoxycholic acid + NAD+

1.1.1.164

hexadecanal + NADH = hexadecanol + NAD+

286098

1.1.1.169

2-dehydropantoate + NADH + H+ = (R)-pantoate + NAD+

1.1.1.17

D-fructose 6-phosphate + NADH + H+ = D-mannitol 1-phosphate + NAD+

1.1.1.172

2-oxoadipate + NADH = 2-hydroxyadipate + NAD+

286113, 286112

1.1.1.176

12-ketochenodeoxycholic acid + NADH = cholic acid + NAD+

indole-3-acetaldehyde + NADH = indole-3-ethanol + NAD+

286151, 286153, 286152, 286154

1.1.1.195

cinnamaldehyde + NADH + H+ = cinnamyl alcohol + NAD+

1.1.1.199

L-usnic acid + NADH = NAD+ + 2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methyl-phenyl)-3-hydroxy-6-methyl-cyclohexa-2,4-dienone

1.1.1.202

3 entries

1.1.1.212

acetoacetyl-[acyl-carrier protein] + NADH = 3-hydroxybutanoyl-[acyl-carrier protein] + NAD+

285678

1.1.1.237

3-(4-hydroxyphenyl)pyruvate + NADH + H+ = 3-(4-hydroxyphenyl)lactate + NAD+

1.1.1.24

3-dehydroquinate + NADH = quinate + NAD+

1.1.1.250

D-ribulose + NADH = D-arabinitol + NAD+

1.1.1.255

D-talose + NADH = D-altritol + NAD+

6-methylhept-5-en-2-one + NADH = 6-methylhept-5-en-2-ol + NAD+

207953, 207955, 207954

2-formylglutarate + NADH + H+ = 2-hydroxymethylglutarate + NAD+

diacetyl + NADH + H+ = (R)-acetoin + NAD+

1.1.1.304

diacetyl + NADH + H+ = (S)-acetoin + NAD+

1.1.1.307

D-xylose + NADH + H+ = xylitol + NAD+

1.1.1.309

phosphonoacetaldehyde + NADH + H+ = 2-hydroxyethylphosphonate + NAD+

1.1.1.32

2 entries

1.1.1.337

a 2-oxocarboxylate + NADH + H+ = (2S)-2-hydroxycarboxylate + NAD+

1.1.1.35

3-oxoacyl-CoA + NADH = 3-hydroxyacyl-CoA + NAD+

1.1.1.36

2 entries

1.1.1.364

dTDP-4-dehydro-6-deoxy-alpha-D-gulopyranose + NADH + H+ = dTDP-6-deoxy-alpha-D-allopyranose + NAD+

1.1.1.37

3 entries

1.1.1.373

3-sulfolactaldehyde + NADH + H+ = 2,3-dihydroxypropane-1-sulfonate + NAD+

12alpha-hydroxy-3-oxo-5beta-cholan-24-oic acid + NADH + H+ = 3alpha,12alpha-dihydroxy-5beta-cholan-24-oic acid + NAD+

1.1.1.399

2-oxoglutarate + NADH + H+ = (R)-2-hydroxyglutarate + NAD+

1.1.1.4

4 entries

1.1.1.404

2,3,5,6-tetrachloro-1,4-benzoquinone + NADH + H+ = 2,3,5,6-tetrachlorohydroquinone + NAD+

1.1.1.406

3 entries

1.1.1.50

5alpha-dihydrotestosterone + NADH = 3alpha-androstanediol + NAD+

1.1.1.60

tartronate semialdehyde + NADH = (R)-glycerate + NAD+

D-fructose + NADH + H+ = D-mannitol + NAD+

1.1.1.69

5-dehydro-D-gluconate + NADH + H+ = D-gluconate + NAD+

1.1.1.71

retinaldehyde + NADH = retinol + NAD+

1.1.1.76

(2S)-acetoin + NADH + H+ = (2S,3S)-butane-2,3-diol + NAD+

1.1.1.78

methylglyoxal + NADH = (R)-lactaldehyde + NAD+

207976, 207968, 207975, 137611, 207969

1.1.1.8

4 entries

1.1.1.81

hydroxypyruvate + NADH + H+ = D-glycerate + NAD+

1.1.1.86

(S)-2-acetolactate + NADH + H+ = (R)-2,3-dihydroxyisovalerate + NAD+

1.1.1.88

2 entries

1.1.1.9

D-xylulose + NADH + H+ = xylitol + NAD+

norsolorinate + NADH + H+ = (1'S)-averantin + NAD+

1.1.1.B40

17,21-dihydroxy-pregn-4-ene-3,11,20-trione + NADH = 11beta,17,21-trihydroxy-pregn-4-ene-3,20-dione + NAD+

285953

1.1.1.B52

3-quinuclidinone + NADH + H+ = (R)-3-quinuclidinol + NAD+

1.11.1.1

3 entries

1.11.1.23

(S)-2-hydroxypropylphosphonic acid + 2 NADH + O2 = cis-(1R,2S)-epoxypropylphosphonic acid + 2 H2O + 2 NAD+

1.12.1.2

H+ + NADH = H2 + NAD+

1.12.1.4

NADH + H+ + reduced ferredoxin = H2 + NAD+ + oxidized ferredoxin

1.13.11.79

FMNH2 + NADH + H+ + O2 + alloxan = 5,6-dimethylbenzimidazole + D-erythrose 4-phosphate + NAD+ + dialuric acid