Ligand ubiquinol

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Basic Ligand Information

Molecular Structure
Picture of ubiquinol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C14H20O4
ubiquinol
TVLSKGDBUQMDPR-UHFFFAOYSA-N
Synonyms:
coenzyme Q1H2, reduced 2,3-dimethoxy-5-methyl-6-(3-methyl-2-butenyl)-1,4-benzoquinone, reduced coenzyme Q1, reduced ubiquinone, reduced ubiquinone-1, reduced ubiquinone 1, ubihydroquinone-1, ubiquinol-1, ubiquinol 1, ubiquinol Q1

Show all pahtways known for Show all pathways known for ubiquinol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acetaldehyde + ubiquinol = ethanol + ubiquinone
show the reaction diagram
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ubiquinol + O2 + H+[side 1] = ubiquinone + H2O + H+[side 2]
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (38 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-malate + ubiquinone = oxaloacetate + ubiquinol
show the reaction diagram
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choline + coenzyme Q1 = betaine aldehyde + reduced coenzyme Q1
show the reaction diagram
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D-fructose + ubiquinone = 5-dehydro-D-fructose + ubiquinol
show the reaction diagram
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(S)-2-hydroxyglutarate + ubiquinone = 2-oxoglutarate + ubiquinol
show the reaction diagram
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phenylacetyl-CoA + H2O + ubiquinone = phenylglyoxylyl-CoA + ubiquinol
show the reaction diagram
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caffeine + ubiquinone + H2O = 1,3,7-trimethylurate + ubiquinol
show the reaction diagram
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pyruvate + ubiquinone + H2O = acetate + CO2 + ubiquinol
show the reaction diagram
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acetaldehyde + ubiquinone = acetate + ubiquinol
show the reaction diagram
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CO + ubiquinone + H2O = CO2 + ubiquinol
show the reaction diagram
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succinate + ubiquinone = fumarate + ubiquinol
show the reaction diagram
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(S)-dihydroorotate + ubiquinone = orotate + ubiquinol
show the reaction diagram
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protoporphyrinogen IX + 3 ubiquinone = protoporphyrin IX + 3 ubiquinol
show the reaction diagram
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NADH + H+ + ubiquinone = NAD+ + ubiquinol
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nitrite + ubiquinone + H2O = nitrate + ubiquinol
show the reaction diagram
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ubiquinone + NAD(P)H = ubiquinol + NAD(P)+
show the reaction diagram
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sulfide + ubiquinone-1 = sulfur + ubiquinol-1
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2 thiosulfate + ubiquinone = tetrathionate + ubiquinol
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (35 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ubiquinol-1 + O2 = ubiquinone-1 + H2O
show the reaction diagram
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nicotinamide riboside + reduced coenzyme Q1 = dihydronicotinamide riboside + coenzyme Q1
show the reaction diagram
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nitrate + ubiquinol = nitrite + ubiquinone + H2O
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (147 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-lactate + ubiquinone = pyruvate + ubiquinol
show the reaction diagram
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D-lactate + ubiquinone 1 = pyruvate + reduced ubiquinone 1
show the reaction diagram
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D-glucose + coenzyme Q1 = D-glucono-1,5-lactone + reduced coenzyme Q1
show the reaction diagram
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choline + coenzyme Q1 = betaine aldehyde + reduced coenzyme Q1
show the reaction diagram
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D-fructose + ubiquinone = 5-dehydro-D-fructose + ubiquinol
show the reaction diagram
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cellobiose + ubiquinone = cellobiono-1,5-lactone + reduced ubiquinone
show the reaction diagram
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(S)-2-hydroxyglutarate + ubiquinone = 2-oxoglutarate + ubiquinol
show the reaction diagram
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N-benzyldihydronicotinamide + oxidized coenzyme Q1 = N-benzylnicointamide + reduced coenzyme Q1
show the reaction diagram
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phenylacetyl-CoA + H2O + ubiquinone = phenylglyoxylyl-CoA + ubiquinol
show the reaction diagram
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caffeine + ubiquinone + H2O = 1,3,7-trimethylurate + ubiquinol
show the reaction diagram
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pyruvate + ubiquinone + H2O = acetate + CO2 + ubiquinol
show the reaction diagram
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acetaldehyde + ubiquinone = acetate + ubiquinol
show the reaction diagram
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protoporphyrinogen IX + 3 ubiquinone = protoporphyrin IX + 3 ubiquinol
show the reaction diagram
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succinate + ubiquinone = fumarate + ubiquinol
show the reaction diagram
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D-proline + H2O + coenzyme Q1 = DELTA1-pyrroline-2-carboxylate + NH3 + reduced coenzyme Q1
show the reaction diagram
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N6-(2-isopentenyl)adenine + coenzyme Q1 = adenine + 3-methylbut-2-enal + reduced coenzyme Q1
show the reaction diagram
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L-proline + coenzyme Q1 + H2O = DELTA1-pyrroline-5-carboxylate + reduced coenzyme Q1
show the reaction diagram
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nitrite + ubiquinone + H2O = nitrate + ubiquinol
show the reaction diagram
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2 thiosulfate + ubiquinone = tetrathionate + ubiquinol
show the reaction diagram
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Enzyme Cofactor/Cosubstrate (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
product inhibition
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (3 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
140
160
pH 7.0, 22C

KM Value (44 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.111
-
pH 7.5, temperature not specified in the publication

References & Links

Links to other databases for ubiquinol

ChEBI
PubChem
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PubChem