Data extracted from this reference:
Activating Compound
hydroxylamine
stimulation at high concentrations
Sus scrofa
Inhibitors
3-Amino-3-deoxy-D-arabinose
Sus scrofa
D-arabinose
competitive inhibition of L-fucose oxidation at 2.5 mM
Sus scrofa
p-hydroxymercuribenzoate
20% loss of activity, saturated
Sus scrofa
sodium iodoacetate
20% loss of activity at 20 mM, pH 8.0
Sus scrofa
KM Value [mM]
0.32
6-deoxy-L-galactose
Sus scrofa
2.1
D-arabinose
Sus scrofa
8
3-amino-D-arabinose
Sus scrofa
Natural Substrates/ Products (Substrates)
3-amino-3-deoxy-D-arabinose + NAD+
Sus scrofa
15% of the activity compared to L-fucose
3-amino-3-deoxy-D-arabino-1,5-lactone + NADH
Sus scrofa
?
6-deoxy-L-galactose + NAD+
Sus scrofa
i.e. L-fucose
6-deoxy-L-galactono-1,5-lactone + NADH
Sus scrofa
?
D-arabinose + NAD+
Sus scrofa
66% of the activity compared to L-fucose
D-arabinono-1,4-lactone + NADH
Sus scrofa
?
D-lyxose + NAD+
Sus scrofa
4% of the activity compared to L-fucose
? + NADH
Sus scrofa
?
L-galactose + NAD+
Sus scrofa
13% of the activity compared to L-fucose
L-galactono-1,5-lactone + NADH
Sus scrofa
?
L-xylose + NAD+
Sus scrofa
4% of the activity compared to L-fucose
L-xylono-1,5-lactone + NADH
Sus scrofa
?
Organism
Purification (Commentary)
to homogeneity, chromatography steps, preparative gel electrophoresis
Sus scrofa
Source Tissue
Specific Activity [micromol/min/mg]
433
purified enzyme
Sus scrofa
Substrates and Products (Substrate)
3-amino-3-deoxy-D-arabinose + NAD+
15% of the activity compared to L-fucose
285806
Sus scrofa
3-amino-3-deoxy-D-arabino-1,5-lactone + NADH
285806
Sus scrofa
?
3-amino-D-arabinose + NAD+
285806
Sus scrofa
3-amino-D-arabino-1,5-lactone + NADH + H+
r
6-deoxy-L-galactose + NAD+
i.e. L-fucose
285806
Sus scrofa
6-deoxy-L-galactono-1,5-lactone + NADH
285806
Sus scrofa
?
D-arabinose + NAD+
66% of the activity compared to L-fucose
285806
Sus scrofa
D-arabinono-1,4-lactone + NADH
285806
Sus scrofa
?
D-lyxose + NAD+
4% of the activity compared to L-fucose
285806
Sus scrofa
? + NADH
285806
Sus scrofa
?
L-galactose + NAD+
13% of the activity compared to L-fucose
285806
Sus scrofa
L-galactono-1,5-lactone + NADH
285806
Sus scrofa
?
L-xylose + NAD+
4% of the activity compared to L-fucose
285806
Sus scrofa
L-xylono-1,5-lactone + NADH
285806
Sus scrofa
?
pH Optimum
Cofactor
NAD+
NAD-specific
Sus scrofa
Activating Compound (protein specific)
hydroxylamine
stimulation at high concentrations
Sus scrofa
Cofactor (protein specific)
NAD+
NAD-specific
Sus scrofa
Inhibitors (protein specific)
3-Amino-3-deoxy-D-arabinose
Sus scrofa
D-arabinose
competitive inhibition of L-fucose oxidation at 2.5 mM
Sus scrofa
p-hydroxymercuribenzoate
20% loss of activity, saturated
Sus scrofa
sodium iodoacetate
20% loss of activity at 20 mM, pH 8.0
Sus scrofa
KM Value [mM] (protein specific)
0.32
6-deoxy-L-galactose
Sus scrofa
2.1
D-arabinose
Sus scrofa
8
3-amino-D-arabinose
Sus scrofa
Natural Substrates/ Products (Substrates) (protein specific)
3-amino-3-deoxy-D-arabinose + NAD+
Sus scrofa
15% of the activity compared to L-fucose
3-amino-3-deoxy-D-arabino-1,5-lactone + NADH
Sus scrofa
?
6-deoxy-L-galactose + NAD+
Sus scrofa
i.e. L-fucose
6-deoxy-L-galactono-1,5-lactone + NADH
Sus scrofa
?
D-arabinose + NAD+
Sus scrofa
66% of the activity compared to L-fucose
D-arabinono-1,4-lactone + NADH
Sus scrofa
?
D-lyxose + NAD+
Sus scrofa
4% of the activity compared to L-fucose
? + NADH
Sus scrofa
?
L-galactose + NAD+
Sus scrofa
13% of the activity compared to L-fucose
L-galactono-1,5-lactone + NADH
Sus scrofa
?
L-xylose + NAD+
Sus scrofa
4% of the activity compared to L-fucose
L-xylono-1,5-lactone + NADH
Sus scrofa
?
Purification (Commentary) (protein specific)
to homogeneity, chromatography steps, preparative gel electrophoresis
Sus scrofa
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
433
purified enzyme
Sus scrofa
Substrates and Products (Substrate) (protein specific)
3-amino-3-deoxy-D-arabinose + NAD+
15% of the activity compared to L-fucose
285806
Sus scrofa
3-amino-3-deoxy-D-arabino-1,5-lactone + NADH
285806
Sus scrofa
?
3-amino-D-arabinose + NAD+
285806
Sus scrofa
3-amino-D-arabino-1,5-lactone + NADH + H+
r
6-deoxy-L-galactose + NAD+
i.e. L-fucose
285806
Sus scrofa
6-deoxy-L-galactono-1,5-lactone + NADH
285806
Sus scrofa
?
D-arabinose + NAD+
66% of the activity compared to L-fucose
285806
Sus scrofa
D-arabinono-1,4-lactone + NADH
285806
Sus scrofa
?
D-lyxose + NAD+
4% of the activity compared to L-fucose
285806
Sus scrofa
? + NADH
285806
Sus scrofa
?
L-galactose + NAD+
13% of the activity compared to L-fucose
285806
Sus scrofa
L-galactono-1,5-lactone + NADH
285806
Sus scrofa
?
L-xylose + NAD+
4% of the activity compared to L-fucose
285806
Sus scrofa
L-xylono-1,5-lactone + NADH
285806
Sus scrofa
?
pH Optimum (protein specific)
Other publictions for EC 1.1.1.122
741316
Ohshiro
Production and characterizatio ...
Acinetobacter sp., Acinetobacter sp. SA-134
Prep. Biochem. Biotechnol.
44
382-391
2014
-
-
-
-
-
-
6
3
-
-
2
2
-
8
-
-
1
-
-
-
2
-
11
1
1
1
-
1
-
1
-
1
2
-
-
-
-
-
-
2
-
-
-
-
6
-
3
-
-
2
2
-
-
-
1
-
-
2
-
11
1
1
-
1
-
1
-
1
-
-
-
-
-
-
-
681445
Brouns
Crystal structure and biochemi ...
Saccharolobus solfataricus, Saccharolobus solfataricus P2
J. Mol. Biol.
371
1249-1260
2007
-
-
-
1
-
-
-
-
-
1
-
-
-
3
-
-
-
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
719837
Brouns
Identification of the missing ...
Saccharolobus solfataricus, Saccharolobus solfataricus P2
J. Biol. Chem.
281
27378-27388
2006
-
-
1
-
-
-
-
-
-
1
2
-
-
3
-
-
-
-
-
-
-
-
2
1
1
1
-
2
-
1
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
1
2
-
-
-
-
-
-
-
-
-
2
1
1
-
2
-
1
-
-
-
-
-
-
-
-
-
655086
Bakke
-
Improvement in thermal stabili ...
Pseudomonas sp., Pseudomonas sp. No. 1143
Biotechnol. Lett.
24
1075-1078
2002
-
-
-
-
-
1
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
1
-
-
2
-
-
-
-
1
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
285798
Itoh
-
Purification and characterizat ...
Agrobacterium tumefaciens, Agrobacterium tumefaciens K-28
J. Ferment. Bioeng.
77
100-102
1994
-
-
-
-
-
-
4
5
-
-
1
6
-
2
-
-
1
-
-
1
2
-
10
-
-
1
-
1
-
1
-
1
1
-
-
-
-
-
-
1
-
-
-
-
4
-
5
-
-
1
6
-
-
-
1
-
1
2
-
10
-
1
-
1
-
1
-
1
-
-
-
-
-
-
-
285799
Yamamoto-Otake
Cloning and sequencing of the ...
Pseudomonas sp.
Biosci. Biotechnol. Biochem.
58
2281-2282
1994
-
-
1
-
-
-
-
-
-
-
-
1
-
9
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
285800
Tsuji
Purification and some properti ...
Agrobacterium tumefaciens
Biochim. Biophys. Acta
1117
167-173
1992
-
1
-
-
-
1
4
4
-
-
3
3
-
10
-
-
1
-
-
1
1
1
4
1
-
-
-
1
-
-
1
1
2
-
-
-
-
1
-
2
-
-
1
-
4
-
4
-
-
3
3
-
-
-
1
-
1
1
1
4
1
-
-
1
-
-
1
1
-
-
-
-
-
-
-
285801
Guimaraes
-
Purification and general prope ...
Aureobasidium pullulans
Arq. Biol. Tecnol. (Curitiba)
32
575-587
1989
-
-
-
-
-
-
2
4
-
-
1
3
-
1
-
-
1
-
-
1
-
1
3
1
-
-
-
1
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
2
-
4
-
-
1
3
-
-
-
1
-
1
-
1
3
1
-
-
1
-
1
-
-
-
-
-
-
-
-
-
285802
Sasajima
Oxidation of L-glucose by a ps ...
Trinickia caryophylli
Biochim. Biophys. Acta
571
120-126
1979
-
-
-
-
-
1
4
4
-
-
1
7
-
1
-
-
1
-
-
1
1
1
7
-
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
2
-
-
1
-
4
-
4
-
-
1
7
-
-
-
1
-
1
1
1
7
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
285805
Endo
Isolation and characterization ...
Oryctolagus cuniculus
J. Biochem.
86
1559-1565
1979
-
-
-
-
-
-
4
3
-
-
1
4
-
6
-
-
1
-
-
3
1
1
4
-
-
1
-
1
-
1
-
1
1
-
-
-
-
-
-
1
-
-
-
-
4
-
3
-
-
1
4
-
-
-
1
-
3
1
1
4
-
1
-
1
-
1
-
1
-
-
-
-
-
-
-
285803
Mobley
The physical properties of NAD ...
Ovis aries aries
Arch. Biochem. Biophys.
186
184-188
1978
5
-
-
-
-
1
3
1
-
-
3
2
-
3
-
-
1
-
-
2
-
1
2
1
-
-
-
2
-
-
-
-
1
-
-
-
5
-
-
1
-
-
1
-
3
-
1
-
-
3
2
-
-
-
1
-
2
-
1
2
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
285804
Mobley
L-Fucose dehydrogenase from sh ...
Ovis aries aries
Methods Enzymol.
41B
173-177
1975
-
-
-
-
-
1
-
6
-
-
1
4
-
3
-
-
1
-
-
2
-
1
4
-
-
-
-
1
-
1
-
-
1
-
-
-
-
-
-
1
-
-
1
-
-
-
6
-
-
1
4
-
-
-
1
-
2
-
1
4
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
285806
Schacter
Isolation of diphosphopyridine ...
Sus scrofa
J. Biol. Chem.
244
4785-4792
1969
1
-
-
-
-
-
4
7
-
-
-
6
-
3
-
-
1
-
-
2
1
-
7
-
-
-
-
-
-
1
-
-
1
-
-
-
1
-
-
1
-
-
-
-
4
-
7
-
-
-
6
-
-
-
1
-
2
1
-
7
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-