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Literature summary for 1.1.1.140 extracted from

  • Kim, H.; Ahn, J.C.; Choi, J.; Hwang, B.; Choi, D.
    Expression and cloning of the full-length cDNA for sorbitol-6-phosphate dehydrogenase and NAD-dependent sorbitol dehydrogenase from pear (Pyrus pyrifolia N.) (2007), Sci. Hortic., 112, 406-412.
No PubMed abstract available
Search for more literature for 1.1.1.140

Cloned(Commentary)

Cloned (Comment) Organism
-
 Pyrus pyrifolia

Inhibitors

Inhibitors Comment Organism Structure
3-(5-((E)-[3,5-bis(methoxycarbonyl)phenyl]diazenyl)-2-hydroxyphenyl)propanoic acid enzyme inhibition is accompanied by a decrease in total prostaglandin F2alpha Pyrus pyrifolia
5-([5-(3-chlorophenyl)furan-2-yl]methyl)-1,3-thiazolidine-2,4-dione
-
 Pyrus pyrifolia
disodium 4-(5-[(Z)-(4-oxido-2-oxo-1,3-thiazol-5(2H)-ylidene)methyl]furan-2-yl)benzoate reduces deactivated prostaglandin F2alpha metabolite production in outer root sheath keratinocyte supernatant Pyrus pyrifolia
ethyl 3-(5-[(2,4-dioxo-1,3-thiazolidin-5-yl)methyl]furan-2-yl)benzoate
-
 Pyrus pyrifolia
methyl 3-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)propanoate
-
 Pyrus pyrifolia

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
34900
-
 x * 34900, calculated Pyrus pyrifolia

Organism

Organism UniProt Comment Textmining
Pyrus pyrifolia Q6L5U3 fragment
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf high level of expression at 30 days after full blooming, expression decreases at 38 days after full blooming and then is maintained at a constant level Pyrus pyrifolia
-

Subunits

Subunits Comment Organism
? x * 34900, calculated Pyrus pyrifolia

pI Value

Organism Comment pI Value Maximum pI Value
Pyrus pyrifolia calculated
-
 6.9

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00015
-
 pH 7.5, 37°C Pyrus pyrifolia 3-(5-((E)-[3,5-bis(methoxycarbonyl)phenyl]diazenyl)-2-hydroxyphenyl)propanoic acid
0.0003
-
 pH 7.5, 37°C Pyrus pyrifolia disodium 4-(5-[(Z)-(4-oxido-2-oxo-1,3-thiazol-5(2H)-ylidene)methyl]furan-2-yl)benzoate
0.0046
-
 pH 7.5, 37°C Pyrus pyrifolia ethyl 3-(5-[(2,4-dioxo-1,3-thiazolidin-5-yl)methyl]furan-2-yl)benzoate
0.0051
-
 pH 7.5, 37°C Pyrus pyrifolia 5-([5-(3-chlorophenyl)furan-2-yl]methyl)-1,3-thiazolidine-2,4-dione
0.015
-
 pH 7.5, 37°C Pyrus pyrifolia methyl 3-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)propanoate