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Literature summary for 1.1.1.141 extracted from

  • Kim, H.J.; Lee, S.; Lee, H.Y.; Won, H.; Chang, S.H.; Nah, S.S.
    15-hydroxyprostaglandin dehydrogenase is upregulated by hydroxychloroquine in rheumatoid arthritis fibroblast-like synoviocytes (2015), Mol. Med. Rep., 12, 4141-4148.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.1.1.141

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
prostaglandin E2 + NAD+ Homo sapiens
-
 15-oxoprostaglandin E2 + NADH + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P15428
-
-

Source Tissue

Source Tissue Comment Organism Textmining
synoviocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
prostaglandin E2 + NAD+
-
 Homo sapiens 15-oxoprostaglandin E2 + NADH + H+
-
 ?

Synonyms

Synonyms Comment Organism
HPGD
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens 15-hydroxyprostaglandin dehydrogenase is upregulated by hydroxychloroquine in rheumatoid arthritis fibroblast-like synoviocytes up