Cloned (Comment) | Organism |
---|---|
expressed in HEK-293 cells, co-expression of hexose-6-phosphate dehydrogenase is not required for the enzyme to function effectively as an oxo-reductase | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
18beta-glycyrrhetinic acid | 11beta-HSD1 inhibitor with submicromolar potency | Homo sapiens | |
18beta-glycyrrhetinic acid | 11beta-HSD1 inhibitor with submicromolar potency | Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
33500 | - |
calculated from amino acid sequence | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
3T3-L1 cell | - |
Mus musculus | - |
adipocyte | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cortisol + NADP+ | - |
Mus musculus | cortisone + NADPH | - |
r | |
cortisol + NADP+ | - |
Homo sapiens | cortisone + NADPH | - |
r |
Synonyms | Comment | Organism |
---|---|---|
11beta-HSD1 | - |
Mus musculus |
11beta-HSD1 | - |
Homo sapiens |
11beta-hydroxysteroid dehydrogenase type 1 | - |
Mus musculus |
11beta-hydroxysteroid dehydrogenase type 1 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Mus musculus | |
NADP+ | - |
Homo sapiens |