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Literature summary for 1.1.1.149 extracted from
- Hydrogen transfer from NADPH to steroid by testicular 20alpha-hydroxysteroid dehydrogenase: stereospecficity and isotope effect (1973), J. Biochem., 74, 1065-1067.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| six step procedure, ammonium sulfate fractionation, chromatography, gel filtration | Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| testis | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 17alpha-hydroxyprogesterone + NADPH + H+ | - |
Sus scrofa | 17alpha,20alpha-dihydroxy-pregn-4-en-3-one + NADP+ | - |
? |  |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADPH | 4A-hydrogen transfer, rate-limiting step | Sus scrofa | |
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Release 2023.1 (January 2023)
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