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Literature summary for 1.1.1.149 extracted from

  • Kwon, S.; Bang, W.; Jeong, J.; Cho, H.; Park, D.; Hwang, J.; Kim, T.; Ko, M.; Cho, I.; Joo, Y.; Jeong, M.; Kim, S.; Kim, C.
    Important role of the C-terminal region of pig aldo-keto reductase family 1 member C1 in the NADPH-dependent reduction of steroid hormones (2013), Indian J. Biochem. Biophys., 50, 237-241.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information a deletion mutant lacking residues R320 to L337 shows higher conversion rates of steroid hormones than wild-type. Especially 5alpha-dihydrotestosterone is more readily reduced Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5alpha-dihydrotestosterone + NADPH + H+
-
Sus scrofa ? + NADP+
-
?

Synonyms

Synonyms Comment Organism
AKR1C1
-
Sus scrofa
aldo-keto reductase family 1 member C1
-
Sus scrofa