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Literature summary for 1.1.1.153 extracted from

  • Maier, J.; Ziegler, I.
    Purification and properties of human sepiapterin reductase from placenta (1993), Adv. Exp. Med. Biol., 338, 199-202.
    View publication on PubMed
Search for more literature for 1.1.1.153

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.006
-
 NADPH
-
 Homo sapiens
0.02
-
 sepiapterin
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
28000
-
 2 * 28000, SDS-PAGE, Western blot analysis with polyclonal rabbit-antiserum, determined by cDNA sequence Homo sapiens
45300
-
 gel filtration Homo sapiens
56000
-
 Western blot analysis with polyclonal rabbit-antiserum Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6-(S)-lactoyl-7,8-dihydropterin + NADPH Homo sapiens
-
 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
placenta
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.93
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6-(S)-lactoyl-7,8-dihydropterin + NADPH
-
 Homo sapiens 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 ?

Subunits

Subunits Comment Organism
homodimer 2 * 28000, SDS-PAGE, Western blot analysis with polyclonal rabbit-antiserum, determined by cDNA sequence Homo sapiens