Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.153 extracted from

  • Dowling, T.G.; O'Rourke, J.F.; Tipton, K.F.
    Sepiapterin reductase and ALR2 ("aldose reductase") from bovine brain (1993), Adv. Exp. Med. Biol., 328, 313-324.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
29500
-
2 * 29500 Bos taurus
59000
-
gel filtration Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6-(S)-lactoyl-7,8-dihydropterin + NADPH Bos taurus
-
6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
9.76
-
-
Bos taurus

Storage Stability

Storage Stability Organism
20°C, after ion exchange chromatography, no change in activity over one year of storage Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6-(S)-lactoyl-7,8-dihydropterin + NADPH
-
Bos taurus 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
?

Subunits

Subunits Comment Organism
homodimer 2 * 29500 Bos taurus