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Literature summary for 1.1.1.179 extracted from
- NADP(+)-dependent D-xylose dehydrogenase from pig liver. Purification and properties (1990), Biochem. J., 266, 637-644.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| L-Lyxose | - |
Sus scrofa |  |
| NAD+ | - |
Sus scrofa | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.09 | - |
NADP+ | - |
Sus scrofa | |
| 6.5 | - |
D-xylose | - |
Sus scrofa | |
| 8.8 | - |
D-xylose | - |
Sus scrofa | |
| 27 | - |
D-ribose | - |
Sus scrofa | |
| 49 | - |
D-glucose | - |
Sus scrofa | |
| 54 | - |
2-deoxy-D-glucose | - |
Sus scrofa | |
| 57 | - |
L-arabinose | - |
Sus scrofa | |
| 130 | - |
D-arabinose | - |
Sus scrofa | |
| 140 | - |
D-galactose | - |
Sus scrofa | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 32000 | - |
2 * 32000, SDS-PAGE | Sus scrofa |
| 62000 | - |
gel filtration | Sus scrofa |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Sus scrofa |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| D-xylose + NADP+ = D-xylono-1,5-lactone + NADPH + H+ | mechanism | Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Sus scrofa | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 7.1 | - |
- |
Sus scrofa |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-deoxy-D-glucose + NADP+ | - |
Sus scrofa | 2-deoxy-D-glucono-1,5-lactone + NADPH + H+ | - |
? | |
| D-arabinose + NADP+ | - |
Sus scrofa | D-arabinono-1,5-lactone + NADPH + H+ | - |
r | |
| D-galactose + NADP+ | - |
Sus scrofa | D-galactono-1,5-lactone + NADPH | - |
? | |
| D-glucose + NADP+ | - |
Sus scrofa | D-glucono-1,5-lactone + NADPH + H+ | - |
? | |
| D-mannose + NADP+ | - |
Sus scrofa | D-mannono-1,5-lactone + NADPH | - |
? | |
| D-ribose + NADP+ | - |
Sus scrofa | ? | - |
? | |
| D-xylose + NADP+ | - |
Sus scrofa | D-xylono-1,5-lactone + NADPH + H+ | - |
? | |
| L-arabinose + NADP+ | - |
Sus scrofa | L-arabinono-1,4-lactone + NADPH | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 32000, SDS-PAGE | Sus scrofa |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Sus scrofa |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 9 | - |
D-arabinose | - |
Sus scrofa | |
| 12 | - |
D-galactose | - |
Sus scrofa | |
| 16 | - |
D-glucose | - |
Sus scrofa | |
| 22 | - |
2-deoxy-D-glucose | - |
Sus scrofa | |
| 40 | - |
D-ribose | - |
Sus scrofa | |
| 45 | - |
L-arabinose | - |
Sus scrofa | |
| 58 | - |
D-xylose | - |
Sus scrofa | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
- |
Sus scrofa |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| additional information | not: NAD+ | Sus scrofa | |
| NADP+ | - |
Sus scrofa | |
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