Literature summary for 1.1.1.184 extracted from

Soni, P.; Kansal, H.; Banerjee, U.C.
Optimization of process parameters for the production of carbonyl reductase by Candida viswanathii in a laboratory-scale fermentor (2008), J. Ind. Microbiol. Biotechnol., 35, 167-173.

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Application

Application	Comment	Organism
synthesis	production of carbonyl reductase by Candida viswanathii in 6.6 l fermentor, using controlled pH value at 8.0, aeration rate 1 vvm and an agitation speed of 250 rpm at 25°C. Use of enzyme for preparative scale reduction of N,N-dimethyl-3-keto-2-thienyl-propanamine to (S)-N,N-dimethyl-3-keto-2-thienyl-propanamine	Candida viswanathii

Organism

Organism	UniProt	Comment	Textmining
Candida viswanathii	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
N,N-dimethyl-3-keto-2-thienyl-propanamine + NADPH	-	Candida viswanathii	(S)-N,N-dimethyl-3-keto-2-thienyl-propanamine + NADP+	key intermediate in synthesis of (S)-duloxetine	?

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Release 2023.1 (January 2023)