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Literature summary for 1.1.1.205 extracted from

  • Barjau Perez-Milicua, M.; Zenteno-Savin, T.; Crocker, D.E.; Gallo-Reynoso, J.P.
    Hypoxanthine-guanine phosphoribosyltransferase and inosine 5-monophosphate dehydrogenase activities in three mammalian species: aquatic (Mirounga angustirostris), semi-aquatic (Lontra longicaudis annectens) and terrestrial (Sus scrofa) (2015), Front. Physiol., 6, 212.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble
-
Mirounga angustirostris
-
-
soluble
-
Sus scrofa
-
-
soluble
-
Lontra longicaudis annectens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
IMP + NAD+ + H2O Mirounga angustirostris
-
XMP + NADH + H+
-
?
IMP + NAD+ + H2O Sus scrofa
-
XMP + NADH + H+
-
?
IMP + NAD+ + H2O Lontra longicaudis annectens
-
XMP + NADH + H+
-
?

Organism

Organism UniProt Comment Textmining
Lontra longicaudis annectens
-
-
-
Mirounga angustirostris
-
-
-
Sus scrofa F1SML7 IMPDH1
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
Mirounga angustirostris
-
blood plasma
-
Sus scrofa
-
blood plasma
-
Lontra longicaudis annectens
-
erythrocyte
-
Sus scrofa
-
erythrocyte
-
Lontra longicaudis annectens
-
erythrocyte low activity Mirounga angustirostris
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
IMP + NAD+ + H2O
-
Mirounga angustirostris XMP + NADH + H+
-
?
IMP + NAD+ + H2O
-
Sus scrofa XMP + NADH + H+
-
?
IMP + NAD+ + H2O
-
Lontra longicaudis annectens XMP + NADH + H+
-
?

Synonyms

Synonyms Comment Organism
IMPDH
-
Mirounga angustirostris
IMPDH
-
Sus scrofa
IMPDH
-
Lontra longicaudis annectens
inosine 5-monophosphate dehydrogenase
-
Mirounga angustirostris
inosine 5-monophosphate dehydrogenase
-
Sus scrofa
inosine 5-monophosphate dehydrogenase
-
Lontra longicaudis annectens

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Mirounga angustirostris
NAD+
-
Sus scrofa
NAD+
-
Lontra longicaudis annectens

General Information

General Information Comment Organism
evolution comparison of enzyme activity and purine metabolite concentration in erythrocytes and plasma from a non-diving mammal (domestic pig) than from diving mammals (river otter and northern elephant seal). IMPDH activity in erythrocytes from domestic pig, Sus scrofa, is higher than that of erythrocytes from river otter, Lontra longicaudis annectens, and northern elephant seal, Mirounga angustirostris. IMPDH activities as well as HX, IMP, XMP and guanine (GDP and GTP), and adenine (AMP, ADP and ATP) nucleotides concentrations in plasma and erythrocytes from diving mammals are lower than those from a non-diving mammal Mirounga angustirostris
evolution comparison of enzyme activity and purine metabolite concentration in erythrocytes and plasma from a non-diving mammal (domestic pig) than from diving mammals (river otter and northern elephant seal). IMPDH activity in erythrocytes from domestic pig, Sus scrofa, is higher than that of erythrocytes from river otter, Lontra longicaudis annectens, and northern elephant seal, Mirounga angustirostris. IMPDH activities as well as HX, IMP, XMP and guanine (GDP and GTP), and adenine (AMP, ADP and ATP) nucleotides concentrations in plasma and erythrocytes from diving mammals are lower than those from a non-diving mammal Sus scrofa
evolution comparison of enzyme activity and purine metabolite concentration in erythrocytes and plasma from a non-diving mammal (domestic pig) than from diving mammals (river otter and northern elephant seal). IMPDH activity in erythrocytes from domestic pig, Sus scrofa, is higher than that of erythrocytes from river otter, Lontra longicaudis annectens, and northern elephant seal, Mirounga angustirostris. IMPDH activities as well as HX, IMP, XMP and guanine (GDP and GTP), and adenine (AMP, ADP and ATP) nucleotides concentrations in plasma and erythrocytes from diving mammals are lower than those from a non-diving mammal Lontra longicaudis annectens