Protein Variants | Comment | Organism |
---|---|---|
C303D | introduction of residue from binding pocket of isoform ALR1 into ALR2, analysis of binding properties of inhibitors | Homo sapiens |
F121P | introduction of residue from binding pocket of isoform ALR1 into ALR2, analysis of binding properties of inhibitors | Homo sapiens |
L300A | introduction of residue from binding pocket of isoform ALR1 into ALR2, analysis of binding properties of inhibitors | Homo sapiens |
L301M | introduction of residue from binding pocket of isoform ALR1 into ALR2, analysis of binding properties of inhibitors | Homo sapiens |
S302R | introduction of residue from binding pocket of isoform ALR1 into ALR2, analysis of binding properties of inhibitors | Homo sapiens |
V47I | introduction of residue from binding pocket of isoform ALR1 into ALR2, analysis of binding properties of inhibitors | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2-[(4-bromo-2-fluorobenzyl)carbamoyl]-5-chlorophenoxy)acetic acid | thermodynamic binding data for isoform ALR2 and mutants | Homo sapiens | |
(3-[(5-chloro-1,3-benzothiazol-2-yl)methyl]-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid | thermodynamic binding data for isoform ALR2 and mutants | Homo sapiens | |
(5-chloro-2-[(3-nitrobenzyl)carbamoyl]phenoxy)acetic acid | thermodynamic binding data for isoform ALR2 and mutants | Homo sapiens | |
fidarestat | thermodynamic binding data for isoform ALR2 and mutants | Homo sapiens | |
sorbinil | thermodynamic binding data for isoform ALR2 and mutants | Homo sapiens | |
Tolrestat | thermodynamic binding data for isoform ALR2 and mutants | Homo sapiens | |
zopolrestat | thermodynamic binding data for isoform ALR2 and mutants | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P15121 | isoform ALR2 | - |