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Literature summary for extracted from

  • Dewanjee, S.; Gangopadhyay, M.; Das, U.; Sahu, R.; Khanra, R.
    Enhanced rosmarinic acid biosynthesis in Solenostemon scutellarioides culture: a precursor-feeding strategy (2014), Nat. Prod. Res., 28, 1691-1698.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
L-tyrosine activates the enzyme Coleus scutellarioides


Protein Variants Comment Organism
additional information cultures fed with precursors, namely L-Phe, L-Tyr, and cucumber juice, at different concentrations show Phe an 1.5, 2.1, and 1.6fold increase in rosmarinic acid accumulation within 48-72 h, respectively. In this study, we focused on the function of individual precursor on key enzymes involved in RA biosynthesis. The phenylalanine ammonia lyase activity was significantly upregulated after Phe feeding, while tyrosine aminotransferase and hydroxyphenylpyruvate reductase activities are improved with Tyr treatment. Rosmarinic acid synthase activity is significantly enhanced by all three precursors, overview Coleus scutellarioides


Organism UniProt Comment Textmining
Coleus scutellarioides

General Information

General Information Comment Organism
metabolism the key enzyme is involved in rosmarinic acid biosynthesis Coleus scutellarioides