Crystallization (Comment) | Organism |
---|---|
- |
Pyricularia grisea |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Tricyclazole | binds at the active site in the vicinity of the NADPH nicotinamide ring | Pyricularia grisea |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
1,3,6,8-Tetrahydroxynaphthalene + NADPH | Pyricularia grisea | essential reaction in the biosynthesis of melanin | Scytalone + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pyricularia grisea | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1,3,6,8-Tetrahydroxynaphthalene + NADPH | - |
Pyricularia grisea | Scytalone + NADP+ | - |
? | |
1,3,6,8-Tetrahydroxynaphthalene + NADPH | essential reaction in the biosynthesis of melanin | Pyricularia grisea | Scytalone + NADP+ | - |
? | |
1,3,8-trihydroxynaphthalene + NADPH + H+ | - |
Pyricularia grisea | vermelone + NADP+ | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | coenzyme specificity is partly conferred by the interaction of a single basic residue, Arg39, with the 2' phosphate group of NADPH | Pyricularia grisea |