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Literature summary for 1.1.1.27 extracted from
- Alpha-hydroxybutyrate dehydrogenase as a biomarker for predicting systemic lupus erythematosus with liver injury (2019), Int. Immunopharmacol., 77, 105922 .
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | alpha-HBDH is an independent risk factor for systemic lupus erythematosus-related liver injury. alpha-HBDH level is significantly higher in the systemic lupus erythematosus-related liver injury patients than in the non-systemic lupus erythematosus-related liver injury patients. alpha-HBDH is positively correlated with levels of aspartate aminotransferase and lactate dehydrogenase, the aspartate aminotransferase/alanine aminotransferase ratio, and the systemic lupus erythematosus disease activity index 2000, and it is negatively correlated with albumin and C3. The optimal cutoff value of alpha-HBDH for distinguishing systemic lupus erythematosus patients with and without liver injury is 258.50 U/l, which provides a 60.94% sensitivity and a 94.67% specificity | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| alpha-HBDH | - |
Homo sapiens |
| alpha-hydroxybutyrate dehydrogenase | - |
Homo sapiens |
| LDH1 | - |
Homo sapiens |
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