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Literature summary for 1.1.1.270 extracted from

  • Appelkvist, E.L.; Reinhart, M.; Fischer, R.; Billheimer, J.; Dallner, G.
    Presence of individual enzymes of cholesterol biosynthesis in rat liver peroxisomes (1990), Arch. Biochem. Biophys., 282, 318-325.
    View publication on PubMed
Search for more literature for 1.1.1.270

Activating Compound

Activating Compound Comment Organism Structure
additional information no effect, no activation by cholestyramine Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane membrane-bound Rattus norvegicus 16020
-
microsome
-
 Rattus norvegicus
-
-
additional information
-
 Rattus norvegicus
-
-
peroxisome
-
 Rattus norvegicus 5777
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus enzyme of cholesterol biosynthesis ?
-
 ?
additional information Rattus norvegicus enzyme of mevalonate pathway for biosynthesis of cholesterol from lanosterol ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 male sprague-dawley rats
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4,4-gem-dimethyl-5alpha-cholest-7-en-3-one + NADPH
-
 Rattus norvegicus 4,4-gem-dimethyl-5alpha-cholest-7-en-3beta-ol + NADP+
-
 ?
additional information enzyme of cholesterol biosynthesis Rattus norvegicus ?
-
 ?
additional information enzyme of mevalonate pathway for biosynthesis of cholesterol from lanosterol Rattus norvegicus ?
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Rattus norvegicus