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Literature summary for 1.1.1.275 extracted from

  • Bouwmeester, H.J.; Gershenzon, J.; Konings, M.C.J.M.; Croteau, R.
    Biosynthesis of the monoterpenes limonene and carvone in the fruit of caraway. I. Demonstration of enzyme activities and their changes with development (1998), Plant Physiol., 117, 901-912.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Carum carvi 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(+)-trans-carveol + NAD+ Carum carvi enzyme catalyses the final step of (+)-carvone biosynthesis, which is developmentally regulated, key enzyme of the pathway is limonene-6-hydroxylase (+)-carvone + NADH
-
?

Organism

Organism UniProt Comment Textmining
Carum carvi
-
var. Karzo
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Source Tissue

Source Tissue Comment Organism Textmining
fruit
-
Carum carvi
-
additional information developmental regulation, overview Carum carvi
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(+)-trans-carveol + NAD+ best substrate Carum carvi (+)-carvone + NADH
-
?
(+)-trans-carveol + NAD+ stereospecificity Carum carvi (+)-carvone + NADH
-
?
(+)-trans-carveol + NAD+ enzyme catalyses the final step of (+)-carvone biosynthesis, which is developmentally regulated, key enzyme of the pathway is limonene-6-hydroxylase Carum carvi (+)-carvone + NADH
-
?
(-)-cis-carveol + NAD+ 65% activity compared to (+)/(-)-trans-carveol Carum carvi (-)-carvone + NADH
-
?
(-)-trans-carveol + NAD+ 5% activity compared to (+)/(-)-trans-carveol Carum carvi ?
-
?
(-)-trans-carveol + NAD+ product identification not possible, below detection limit of GC-MS Carum carvi ?
-
?
(-)/(+)-cis-carveol + NAD+
-
Carum carvi (-)-carvone + NADH
-
?

Temperature Optimum [┬░C]

Temperature Optimum [┬░C] Temperature Optimum Maximum [┬░C] Comment Organism
30
-
assay at Carum carvi

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
10
-
about Carum carvi

Cofactor

Cofactor Comment Organism Structure
NAD+ absolutely dependent on, NADP+ cannot substitute for NAD+ and cannot act synergistically Carum carvi