KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0004 | - |
S-hydroxymethyl glutathione | - |
Homo sapiens | |
0.00092 | - |
S-hydroxymethyl glutathione | - |
Rattus norvegicus | |
0.002 | - |
S-hydroxymethyl glutathione | - |
Pisum sativum | |
0.006 | - |
S-hydroxymethyl glutathione | - |
Drosophila melanogaster | |
0.0065 | - |
NAD+ | reaction with S-hydroxymethyl glutathione | Pisum sativum | |
0.04 | - |
S-hydroxymethyl glutathione | - |
Saccharomyces cerevisiae | |
0.094 | - |
S-hydroxymethyl glutathione | - |
Escherichia coli | |
0.14 | - |
NAD+ | reaction with S-hydroxymethyl glutathione | Pisum sativum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
formaldehyde + glutathione + NAD+ | Escherichia coli | - |
S-formylglutathione + NADH + H+ | - |
? | |
formaldehyde + glutathione + NAD+ | Saccharomyces cerevisiae | main enzymatic system responsible for the formaldehyde elimination | S-formylglutathione + NADH + H+ | - |
? | |
formaldehyde + glutathione + NAD+ | Pisum sativum | main enzymatic system responsible for the formaldehyde elimination | S-formylglutathione + NADH + H+ | - |
? | |
formaldehyde + glutathione + NAD+ | Arabidopsis thaliana | main enzymatic system responsible for the formaldehyde elimination | S-formylglutathione + NADH + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | - |
- |
- |
Drosophila melanogaster | - |
alcohol dehydrogenase III | - |
Escherichia coli | - |
alcohol dehydrogenase III | - |
Homo sapiens | - |
class II alcohol dehydrogenase | - |
Pisum sativum | - |
class III alcohol dehydrogenase | - |
Rattus norvegicus | - |
class II alcohol dehydrogenase | - |
Saccharomyces cerevisiae | - |
class III alcohol dehydrogenase | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
formaldehyde + glutathione + NAD+ | - |
Drosophila melanogaster | S-formylglutathione + NADH + H+ | - |
? | |
formaldehyde + glutathione + NAD+ | - |
Escherichia coli | S-formylglutathione + NADH + H+ | - |
? | |
formaldehyde + glutathione + NAD+ | - |
Arabidopsis thaliana | S-formylglutathione + NADH + H+ | - |
? | |
formaldehyde + glutathione + NAD+ | the true substrate is a hemimercaptal, S-hydroxymethylglutathione, spontaneously formed from formaldehyde and glutathione | Homo sapiens | S-formylglutathione + NADH + H+ | - |
? | |
formaldehyde + glutathione + NAD+ | the true substrate is a hemimercaptal, S-hydroxymethylglutathione, spontaneously formed from formaldehyde and glutathione | Rattus norvegicus | S-formylglutathione + NADH + H+ | - |
? | |
formaldehyde + glutathione + NAD+ | the true substrate is a hemimercaptal, S-hydroxymethylglutathione, spontaneously formed from formaldehyde and glutathione | Saccharomyces cerevisiae | S-formylglutathione + NADH + H+ | - |
? | |
formaldehyde + glutathione + NAD+ | the true substrate is a hemimercaptal, S-hydroxymethylglutathione, spontaneously formed from formaldehyde and glutathione | Pisum sativum | S-formylglutathione + NADH + H+ | - |
? | |
formaldehyde + glutathione + NAD+ | main enzymatic system responsible for the formaldehyde elimination | Saccharomyces cerevisiae | S-formylglutathione + NADH + H+ | - |
? | |
formaldehyde + glutathione + NAD+ | main enzymatic system responsible for the formaldehyde elimination | Pisum sativum | S-formylglutathione + NADH + H+ | - |
? | |
formaldehyde + glutathione + NAD+ | main enzymatic system responsible for the formaldehyde elimination | Arabidopsis thaliana | S-formylglutathione + NADH + H+ | - |
? | |
formaldehyde + S-hydroxymethyl glutathione + NAD+ | - |
Drosophila melanogaster | ? | - |
? | |
formaldehyde + S-hydroxymethyl glutathione + NAD+ | - |
Escherichia coli | ? | - |
? | |
formaldehyde + S-hydroxymethyl glutathione + NAD+ | - |
Homo sapiens | ? | - |
? | |
formaldehyde + S-hydroxymethyl glutathione + NAD+ | - |
Rattus norvegicus | ? | - |
? | |
formaldehyde + S-hydroxymethyl glutathione + NAD+ | - |
Saccharomyces cerevisiae | ? | - |
? | |
formaldehyde + S-hydroxymethyl glutathione + NAD+ | - |
Pisum sativum | ? | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
3.33 | - |
S-hydroxymethyl glutathione | - |
Homo sapiens | |
3.6 | - |
S-hydroxymethyl glutathione | - |
Rattus norvegicus | |
6.33 | - |
S-hydroxymethyl glutathione | - |
Pisum sativum | |
16 | - |
S-hydroxymethyl glutathione | - |
Drosophila melanogaster | |
88.3 | - |
S-hydroxymethyl glutathione | - |
Saccharomyces cerevisiae | |
156 | - |
S-hydroxymethyl glutathione | - |
Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Drosophila melanogaster | |
NAD+ | - |
Escherichia coli | |
NAD+ | - |
Homo sapiens | |
NAD+ | - |
Rattus norvegicus | |
NAD+ | - |
Saccharomyces cerevisiae | |
NAD+ | - |
Pisum sativum | |
NAD+ | - |
Arabidopsis thaliana |