Literature summary for 1.1.1.3 extracted from

Park, S.D.; Lee, J.Y.; Sim, S.Y.; Kim, Y.; Lee, H.S.
Characteristics of methionine production by an engineered Corynebacterium glutamicum strain (2007), Metab. Eng., 9, 327-336.

Search for more literature for 1.1.1.3

Cloned(Commentary)

Cloned (Comment)	Organism
introduction of the gene homFBR allele into strain HL1049	Corynebacterium glutamicum

Protein Variants

Protein Variants	Comment	Organism
additional information	engineering of a Corynebacterium glutamicum strain HL1049 for effective production of methionine by elimination of the threonine synthesis gene and desensitizing the homoserine dehydrogenase versus inhibition by threonine, analysis of the amino acid spectrum of the engineered strain, overview	Corynebacterium glutamicum

Inhibitors

Inhibitors	Comment	Organism	Structure
threonine	the methionine-producing strain contains a deregulated homoserine dehydrogenase that is not sensitive to feedback inhibition as the wild-type enzyme	Corynebacterium glutamicum

Organism

Organism	UniProt	Comment	Textmining
Corynebacterium glutamicum	-	a methionine-producing strain carrying mutations in the hom and the thrB genes	-

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
30	-	assay at	Corynebacterium glutamicum

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)