BRENDA - Enzyme Database show
show all sequences of 1.1.1.306

Thiols in nitric oxide synthase-containing Nocardia sp. strain NRRL 5646

Lee, S.; Bergeron, H.; Lau, P.C.; Rosazza, J.P.; Appl. Environ. Microbiol. 73, 3095-3097 (2007)

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
formaldehyde
-
Nocardia sp.
Application
Application
Commentary
Organism
additional information
thiol formation and detection of MSH-dependent formaldehyde dehydrogenase activity in cell extracts are relevant to the possible modulation of nitric oxide toxicity generated by strain NRRL 5646
Nocardia sp.
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Nocardia sp.
-
-
-
Nocardia sp. NRRL 5646
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
mycothiol + NAD+
-
690518
Nocardia sp.
? + NADH + H+
-
-
-
?
mycothiol + NAD+
-
690518
Nocardia sp. NRRL 5646
? + NADH + H+
-
-
-
?
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
-
Nocardia sp.
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
formaldehyde
-
Nocardia sp.
Application (protein specific)
Application
Commentary
Organism
additional information
thiol formation and detection of MSH-dependent formaldehyde dehydrogenase activity in cell extracts are relevant to the possible modulation of nitric oxide toxicity generated by strain NRRL 5646
Nocardia sp.
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
-
Nocardia sp.
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
mycothiol + NAD+
-
690518
Nocardia sp.
? + NADH + H+
-
-
-
?
mycothiol + NAD+
-
690518
Nocardia sp. NRRL 5646
? + NADH + H+
-
-
-
?
Other publictions for EC 1.1.1.306
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
724589
Yoshida
Gene expression analysis of me ...
Rhodococcus erythropolis, Rhodococcus erythropolis N9T-4
Biosci. Biotechnol. Biochem.
75
123-127
2011
-
-
1
-
-
-
-
-
-
-
-
2
-
3
-
-
-
-
-
-
-
-
2
-
1
-
-
-
1
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
1
-
-
-
1
-
-
-
2
1
1
2
-
-
690518
Lee
Thiols in nitric oxide synthas ...
Nocardia sp., Nocardia sp. NRRL 5646
Appl. Environ. Microbiol.
73
3095-3097
2007
1
1
-
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
1
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
654527
Vogt
The metabolism of nitrosothiol ...
Mycolicibacterium smegmatis, Mycolicibacterium smegmatis mc2
Biochem. J.
374
657-666
2003
-
-
-
-
-
-
-
2
-
-
1
-
-
5
-
-
1
-
-
1
1
-
4
1
-
-
-
1
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
2
-
-
1
-
-
-
-
1
-
1
1
-
4
1
-
-
-
1
1
-
-
-
-
-
-
-
-
-
288322
Misset-Smits
Mycothiol, 1-O-(2'-[N-acwtyl-L ...
Amycolatopsis methanolica, Rhodococcus erythropolis
FEBS Lett.
409
221-222
1997
-
-
-
-
-
-
1
-
-
-
-
2
-
5
-
-
-
-
-
2
1
-
2
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
4
-
-
-
-
1
-
-
-
-
-
2
-
-
-
-
-
2
1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
288323
Norin
Mycothiol-dependent formaldehy ...
Amycolatopsis methanolica
Eur. J. Biochem.
248
282-289
1997
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
1
-
-
1
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
288324
Van Ophem
NAD-linked, factor-dependent f ...
Amycolatopsis methanolica
Eur. J. Biochem.
206
511-518
1992
2
-
-
-
-
-
9
8
-
1
2
1
-
7
-
-
1
-
-
1
4
-
3
1
-
-
-
-
2
-
-
1
-
-
-
2
-
-
1
-
-
-
-
9
-
8
-
1
2
1
-
-
-
1
-
1
4
-
3
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-