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Literature summary for 1.1.1.306 extracted from

  • Yoshida, N.; Hayasaki, T.; Takagi, H.
    Gene expression analysis of methylotrophic oxidoreductases involved in the oligotrophic growth of Rhodococcus erythropolis N9T-4 (2011), Biosci. Biotechnol. Biochem., 75, 123-127.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
mFADH genetic organization, overview Rhodococcus erythropolis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-(hydroxymethyl)mycothiol + NAD+ Rhodococcus erythropolis
-
S-formylmycothiol + NADH + H+
-
?
S-(hydroxymethyl)mycothiol + NAD+ Rhodococcus erythropolis N9T-4
-
S-formylmycothiol + NADH + H+
-
?

Organism

Organism UniProt Comment Textmining
Rhodococcus erythropolis
-
-
-
Rhodococcus erythropolis N9T-4
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-(hydroxymethyl)mycothiol + NAD+
-
Rhodococcus erythropolis S-formylmycothiol + NADH + H+
-
?
S-(hydroxymethyl)mycothiol + NAD+
-
Rhodococcus erythropolis N9T-4 S-formylmycothiol + NADH + H+
-
?

Synonyms

Synonyms Comment Organism
mFADH
-
Rhodococcus erythropolis
mycothiol-dependent formaldehyde dehydrogenase
-
Rhodococcus erythropolis

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
assay at Rhodococcus erythropolis

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
assay at Rhodococcus erythropolis

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Rhodococcus erythropolis

Expression

Organism Comment Expression
Rhodococcus erythropolis the gene encoding the enzyme is not induced under oligotrophic conditions additional information
Rhodococcus erythropolis formaldehyde, added to the medium, induces the enzyme expression by 10fold up

General Information

General Information Comment Organism
metabolism the organism has three distinct formaldehyde oxidation systems, the methlotrophhic oxidoreductase mycothiol-dependent formaldehyde dehydroganse is not a key enzyme invovled in oligotrophic growth Rhodococcus erythropolis