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Literature summary for 1.1.1.37 extracted from

  • Kim, S.Y.; Hwang, K.Y.; Kim, S.H.; Sung, H.C.; Han, Y.S.; Cho, Y.
    Structural basis for cold adaptation. Sequence, biochemical properties, and crystal structure of malate dehydrogenase from a psychrophile Aquaspirillium arcticum (1999), J. Biol. Chem., 274, 11761-11767.
    View publication on PubMed
Search for more literature for 1.1.1.37

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.014
-
 oxaloacetate 37°C Thermus thermophilus
0.023
-
 oxaloacetate 4°C Escherichia coli
0.026
-
 oxaloacetate 10°C Escherichia coli
0.056
-
 oxaloacetate 37°C Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
malate + NAD+ Thermus thermophilus
-
 oxaloacetate + NADH + H+
-
 r
malate + NAD+ Escherichia coli
-
 oxaloacetate + NADH + H+
-
 r
malate + NAD+ Sus scrofa
-
 oxaloacetate + NADH + H+
-
 r
malate + NAD+
-
-
 oxaloacetate + NADH + H+
-
 r

Organism

Organism UniProt Comment Textmining
Aquaspirillum arcticum Q9ZF99
-
-
Escherichia coli
-
-
-
Sus scrofa
-
 pig
-
Thermus thermophilus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
 Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-malate + NAD+
-
 Thermus thermophilus oxaloacetate + NADH + H+
-
 r
(S)-malate + NAD+
-
 Escherichia coli oxaloacetate + NADH + H+
-
 r
(S)-malate + NAD+
-
 Sus scrofa oxaloacetate + NADH + H+
-
 r
(S)-malate + NAD+
-
-
 oxaloacetate + NADH + H+
-
 r
malate + NAD+
-
 Thermus thermophilus oxaloacetate + NADH + H+
-
 r
malate + NAD+
-
 Escherichia coli oxaloacetate + NADH + H+
-
 r
malate + NAD+
-
 Sus scrofa oxaloacetate + NADH + H+
-
 r
malate + NAD+
-
-
 oxaloacetate + NADH + H+
-
 r
oxaloacetate + NADH
-
 Thermus thermophilus L-malate + NAD+
-
 r
oxaloacetate + NADH
-
 Escherichia coli L-malate + NAD+
-
 r
oxaloacetate + NADH
-
 Sus scrofa L-malate + NAD+
-
 r
oxaloacetate + NADH
-
-
 L-malate + NAD+
-
 r

Subunits

Subunits Comment Organism
dimer
-
 Thermus thermophilus
dimer
-
 Sus scrofa
dimer
-
-

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
55
-
 retains full activity for more than 2 h Thermus thermophilus
90
-
 fully active for 1 h Thermus thermophilus